Multiple myeloma immunoglobulin lambda translocations portend poor prognosis von Barwick, Benjamin G., Neri, Paola, Bahlis, Nizar J., Nooka, Ajay K., Dhodapkar, Madhav V., Jaye, David L., Hofmeister, Craig C., Kaufman, Jonathan L., Gupta, Vikas A., Auclair, Daniel, Keats, Jonathan J., Lonial, Sagar, Vertino, Paula M., Boise, Lawrence H.

Volltext

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors von Shern, Jack F, Chen, Li, Chmielecki, Juliann, Wei, Jun S, Patidar, Rajesh, Rosenberg, Mara, Ambrogio, Lauren, Auclair, Daniel, Wang, Jianjun, Song, Young K, Tolman, Catherine, Hurd, Laura, Liao, Hongling, Zhang, Shile, Bogen, Dominik, Brohl, Andrew S, Sindiri, Sivasish, Catchpoole, Daniel, Badgett, Thomas, Getz, Gad, Mora, Jaume, Anderson, James R, Skapek, Stephen X, Barr, Frederic G, Meyerson, Matthew, Hawkins, Douglas S, Khan, Javed

Volltext

Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases von Manojlovic, Zarko, Christofferson, Austin, Liang, Winnie S, Aldrich, Jessica, Washington, Megan, Wong, Shukmei, Rohrer, Daniel, Jewell, Scott, Kittles, Rick A, Derome, Mary, Auclair, Daniel, Craig, David Wesley, Keats, Jonathan, Carpten, John D

Volltext

Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma von Samur, Mehmet Kemal, Minvielle, Stephane, Gulla, Annamaria, Fulciniti, Mariateresa, Cleynen, Alice, Aktas Samur, Anil, Szalat, Raphael, Shammas, Masood, Magrangeas, Florence, Tai, Yu-Tzu, Auclair, Daniel, Keats, Jonathan, Richardson, Paul, Attal, Michel, Moreau, Philippe, Anderson, Kenneth C., Parmigiani, Giovanni, Avet-Loiseau, Hervé, Munshi, Nikhil C.

Volltext

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis von WILHELM, Scott M, CARTER, Christopher, CAO, Yichen, SHUJATH, Jaleel, GAWLAK, Susan, EVELEIGH, Deepa, ROWLEY, Bruce, LI LIU, ADNANE, Lila, LYNCH, Mark, AUCLAIR, Daniel, TAYLOR, Ian, TANG, Liya, GEDRICH, Rich, VOZNESENSKY, Andrei, RIEDL, Bernd, POST, Leonard E, BOLLAG, Gideon, TRAIL, Pamela A, WILKIE, Dean, MCNABOLA, Angela, HONG RONG, CHEN, Charles, XIAOMEI ZHANG, VINCENT, Patrick, MCHUGH, Mark

Volltext

Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma von Mikulasova, Aneta, Ashby, Cody, Tytarenko, Ruslana G., Qu, Pingping, Rosenthal, Adam, Dent, Judith A., Ryan, Katie R., Bauer, Michael A., Wardell, Christopher P., Hoering, Antje, Mavrommatis, Konstantinos, Trotter, Matthew, Deshpande, Shayu, Yaccoby, Shmuel, Tian, Erming, Keats, Jonathan, Auclair, Daniel, Jackson, Graham H., Davies, Faith E., Thakurta, Anjan, Morgan, Gareth J., Walker, Brian A.

Volltext

CNV Radar: an improved method for somatic copy number alteration characterization in oncology von Soong, David, Stratford, Jeran, Avet-Loiseau, Herve, Bahlis, Nizar, Davies, Faith, Dispenzieri, Angela, Sasser, A. Kate, Schecter, Jordan M., Qi, Ming, Brown, Chad, Jones, Wendell, Keats, Jonathan J., Auclair, Daniel, Chiu, Christopher, Powers, Jason, Schaffer, Michael

Volltext

DNA Methylation Analysis Determines the High Frequency of Genic Hypomethylation and Low Frequency of Hypermethylation Events in Plasma Cell Tumors von SALHIA, Bodour, BAKER, Angela, AHMANN, Gregory, AUCLAIR, Daniel, FONSECA, Rafael, CARPTEN, John

Volltext

Insights into high-risk multiple myeloma from an analysis of the role of PHF19 in cancer von Ghamlouch, Hussein, Boyle, Eileen M., Blaney, Patrick, Wang, Yubao, Choi, Jinyoung, Williams, Louis, Bauer, Michael, Auclair, Daniel, Bruno, Benedetto, Walker, Brian A., Davies, Faith E., Morgan, Gareth J.

Volltext

A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5 von White, Brian S., Lanc, Irena, O’Neal, Julie, Gupta, Harshath, Fulton, Robert S., Schmidt, Heather, Fronick, Catrina, Belter, Edward A., Fiala, Mark, King, Justin, Ahmann, Greg J., DeRome, Mary, Mardis, Elaine R., Vij, Ravi, DiPersio, John F., Levy, Joan, Auclair, Daniel, Tomasson, Michael H.

Volltext

Extreme body mass index and survival in newly diagnosed multiple myeloma patients von Shah, Urvi A., Whiting, Karissa, Devlin, Sean, Ershler, Rachel, Kanapuru, Bindu, Lee, David J., Tahri, Sabrin, Gwise, Thomas, Rustad, Even H., Mailankody, Sham, Lesokhin, Alexander M., Kazandjian, Dickran, Maura, Francesco, Auclair, Daniel, Birmann, Brenda M., Usmani, Saad Z., Gormley, Nicole, Marinac, Catherine R., Landgren, Ola

Volltext

Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma von Pilcher, William, Thomas, Beena E., Bhasin, Swati S., Jayasinghe, Reyka G., Yao, Lijun, Gonzalez-Kozlova, Edgar, Dasari, Surendra, Kim-Schulze, Seunghee, Rahman, Adeeb, Patton, Jonathan, Fiala, Mark, Cheloni, Giulia, Kourelis, Taxiarchis, Dhodapkar, Madhav V., Vij, Ravi, Mehr, Shaadi, Hamilton, Mark, Cho, Hearn Jay, Auclair, Daniel, Avigan, David E., Kumar, Shaji K., Gnjatic, Sacha, Ding, Li, Bhasin, Manoj

Volltext

Identification of genes modulated in multiple myeloma using genetically identical twin samples von Munshi, Nikhil C., Hideshima, Teru, Carrasco, Daniel, Shammas, Masood, Auclair, Daniel, Davies, Faith, Mitsiades, Nicholas, Mitsiades, Constantine, Kim, Ryung Suk, Li, Cheng, Rajkumar, S. Vincent, Fonseca, Rafael, Bergsagel, Lief, Chauhan, Dharminder, Anderson, Kenneth C.

Volltext

Identification of genes regulated by Dexamethasone in multiple myeloma cells using oligonucleotide arrays von CHAUHAN, Dharminder, AUCLAIR, Daniel, LAN BO CHEN, MUNSHI, Nikhil C, ANDERSON, Kenneth C, ROBINSON, Elisabeth K, HIDESHIMA, Teru, GUILAN LI, PODAR, Klaus, GUPTA, Deepak, RICHARDSON, Paul, SCHLOSSMAN, Robert L, KRETT, Nancy

Volltext

Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors von Chmielecki, Juliann, Crago, Aimee M, Rosenberg, Mara, O'Connor, Rachael, Walker, Sarah R, Ambrogio, Lauren, Auclair, Daniel, McKenna, Aaron, Heinrich, Michael C, Frank, David A, Meyerson, Matthew

Volltext

Serum level of the periostin, a homologue of an insect cell adhesion molecule, as a prognostic marker in nonsmall cell lung carcinomas von Sasaki, Hidefumi, Auclair, Daniel, Fukai, Ichiro, Kiriyama, Masanobu, Yamakawa, Yosuke, Fujii, Yoshitaka, Chen, Lan Bo

Volltext

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma von Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith E., Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Philippe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth J.

Volltext

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis von Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith, Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Phillipe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth

Volltext

Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy von Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Anderson, Kenneth C., Richardson, Paul, Krishnan, Amrita, Lonial, Sagar, Kaufman, Jonathan, Siegel, David S., Vesole, David H., Roy, Vivek, Rivera, Candido E., Rajkumar, S. Vincent, Kumar, Shaji, Fonseca, Rafael, Ahmann, Greg J., Bergsagel, P. Leif, Stewart, A. Keith, Hofmeister, Craig C., Efebera, Yvonne A., Jagannath, Sundar, Chari, Ajai, Trudel, Suzanne, Reece, Donna, Wolf, Jeffrey, Martin, Thomas, Zimmerman, Todd, Rosenbaum, Cara, Jakubowiak, Andrzej J., Lebovic, Daniel, Vij, Ravi, Stockerl-Goldstein, Keith, Getz, Gad, Golub, Todd R.

Volltext

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations von Pugh, Trevor J., Weeraratne, Shyamal Dilhan, Archer, Tenley C., Pomeranz Krummel, Daniel A., Auclair, Daniel, Bochicchio, James, Carneiro, Mauricio O., Carter, Scott L., Cibulskis, Kristian, Erlich, Rachel L., Greulich, Heidi, Lawrence, Michael S., Lennon, Niall J., McKenna, Aaron, Meldrim, James, Ramos, Alex H., Ross, Michael G., Russ, Carsten, Shefler, Erica, Sivachenko, Andrey, Sogoloff, Brian, Stojanov, Petar, Tamayo, Pablo, Mesirov, Jill P., Amani, Vladimir, Teider, Natalia, Sengupta, Soma, Francois, Jessica Pierre, Northcott, Paul A., Taylor, Michael D., Yu, Furong, Crabtree, Gerald R., Kautzman, Amanda G., Gabriel, Stacey B., Getz, Gad, Jäger, Natalie, Jones, David T. W., Lichter, Peter, Pfister, Stefan M., Roberts, Thomas M., Meyerson, Matthew, Pomeroy, Scott L., Cho, Yoon-Jae

Volltext