Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals von Barayeu, Uladzimir, Schilling, Danny, Eid, Mohammad, Xavier da Silva, Thamara Nishida, Schlicker, Lisa, Mitreska, Nikolina, Zapp, Christopher, Gräter, Frauke, Miller, Aubry K., Kappl, Reinhard, Schulze, Almut, Friedmann Angeli, José Pedro, Dick, Tobias P.

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Regulation of mitochondrial morphology and function by stearoylation of TFR1 von Senyilmaz, Deniz, Virtue, Sam, Xu, Xiaojun, Tan, Chong Yew, Griffin, Julian L., Miller, Aubry K., Vidal-Puig, Antonio, Teleman, Aurelio A.

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Elevated Levels of the Reactive Metabolite Methylglyoxal Recapitulate Progression of Type 2 Diabetes von Moraru, Alexandra, Wiederstein, Janica, Pfaff, Daniel, Fleming, Thomas, Miller, Aubry K., Nawroth, Peter, Teleman, Aurelio A.

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Bioinspired Asymmetric Total Synthesis of Emeriones A–C von Jänner, Sven, Isak, Daniel, Li, Yuli, Houk, Kendall N., Miller, Aubry K.

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Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development von Lohbeck, Jasmin, Miller, Aubry K.

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Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid von Lechner, Severin, Steimbach, Raphael R., Wang, Longlong, Deline, Marshall L., Chang, Yun-Chien, Fromme, Tobias, Klingenspor, Martin, Matthias, Patrick, Miller, Aubry K., Médard, Guillaume, Kuster, Bernhard

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Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers von Schilling, Danny, Barayeu, Uladzimir, Steimbach, Raphael R., Talwar, Deepti, Miller, Aubry K., Dick, Tobias P.

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Inclusion Complexes of Gold(I)‐Dithiocarbamates with β‐Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery von Morgen, Michael, Fabrowski, Piotr, Amtmann, Eberhard, Gunkel, Nikolas, Miller, Aubry K.

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Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins von Nůsková, Hana, Serebryakova, Marina V., Ferrer-Caelles, Anna, Sachsenheimer, Timo, Lüchtenborg, Christian, Miller, Aubry K., Brügger, Britta, Kordyukova, Larisa V., Teleman, Aurelio A.

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Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target von Lechner, Severin, Malgapo, Martin Ian P., Grätz, Christian, Steimbach, Raphael R., Baron, Agnes, Rüther, Patrick, Nadal, Simon, Stumpf, Carmen, Loos, Christina, Ku, Xin, Prokofeva, Polina, Lautenbacher, Ludwig, Heimburg, Tino, Würf, Vivian, Meng, Chen, Wilhelm, Mathias, Sippl, Wolfgang, Kleigrewe, Karin, Pauling, Josch K., Kramer, Karl, Miller, Aubry K., Pfaffl, Michael W., Linder, Maurine E., Kuster, Bernhard, Médard, Guillaume

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Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance von Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne, Witt, Olaf, Oehme, Ina

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Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated von Géraldy, Magalie, Morgen, Michael, Sehr, Peter, Steimbach, Raphael R, Moi, Davide, Ridinger, Johannes, Oehme, Ina, Witt, Olaf, Malz, Mona, Nogueira, Mauro S, Koch, Oliver, Gunkel, Nikolas, Miller, Aubry K

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Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase von Herbst-Gervasoni, Corey J, Steimbach, Raphael R, Morgen, Michael, Miller, Aubry K, Christianson, David W

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Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics von Chang, Yun-Chien, Gnann, Christian, Steimbach, Raphael R., Bayer, Florian P., Lechner, Severin, Sakhteman, Amirhossein, Abele, Miriam, Zecha, Jana, Trendel, Jakob, The, Matthew, Lundberg, Emma, Miller, Aubry K., Kuster, Bernhard

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Tetrahydro-β-carboline derivatives as potent histone deacetylase 6 inhibitors with broad-spectrum antiproliferative activity von Chen, Xin, Wang, Jiayun, Zhao, Peng, Dang, Baiyun, Liang, Ting, Steimbach, Raphael R., Miller, Aubry K., Liu, Jia, Wang, Xin, Zhang, Tongtong, Luan, Xiaofa, Hu, Jiadong, Gao, Jinming

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A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering von Sananes, Amiram, Cohen, Itay, Shahar, Anat, Hockla, Alexandra, De Vita, Elena, Miller, Aubry K., Radisky, Evette S., Papo, Niv

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A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion von Zhang, Leran, Lovell, Scott, De Vita, Elena, Jagtap, Pravin Kumar Ankush, Lucy, Daniel, Goya Grocin, Andrea, Kjær, Svend, Borg, Annabel, Hennig, Janosch, Miller, Aubry K., Tate, Edward W.

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Frontispiece: Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers von Schilling, Danny, Barayeu, Uladzimir, Steimbach, Raphael R., Talwar, Deepti, Miller, Aubry K., Dick, Tobias P.

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Preparation of 1-Benzyl-7-methylene-1,5,6,7-tetrahydro-4H-benzo[d]imidazol-4-one von Morgen, Michael

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Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome von Nůsková, Hana, Cortizo, Fabiola Garcia, Schwenker, Lena Sophie, Sachsenheimer, Timo, Diakonov, Egor E., Tiebe, Marcel, Schneider, Martin, Lohbeck, Jasmin, Reid, Carissa, Kopp-Schneider, Annette, Helm, Dominic, Brügger, Britta, Miller, Aubry K., Teleman, Aurelio A.

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