A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors von Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark

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Castration-Resistant Prostate Cancer: Locking Up the Molecular Escape Routes von ATTAR, Ricardo M, TAKIMOTO, Chris H, GOTTARDIS, Marco M

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Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones von de Boer, Bauke, Prick, Janine, Pruis, Maurien G., Keane, Peter, Imperato, Maria Rosaria, Jaques, Jennifer, Brouwers-Vos, Annet Z., Hogeling, Shanna M., Woolthuis, Carolien M., Nijk, Marije T., Diepstra, Arjan, Wandinger, Sebastian, Versele, Matthias, Attar, Ricardo M., Cockerill, Peter N., Huls, Gerwin, Vellenga, Edo, Mulder, André B., Bonifer, Constanze, Schuringa, Jan Jacob

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BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR von Carboni, Joan M, Wittman, Mark, Yang, Zheng, Lee, Francis, Greer, Ann, Hurlburt, Warren, Hillerman, Stephen, Cao, Carolyn, Cantor, Glenn H, Dell-John, Janet, Chen, Cliff, Discenza, Lorell, Menard, Krista, Li, Aixin, Trainor, George, Vyas, Dolatrai, Kramer, Robert, Attar, Ricardo M, Gottardis, Marco M

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Identification of isoquinolinone DHODH inhibitor isosteres von DeRatt, Lindsey G., Zhang, Zhuming, Pietsch, E. Christine, Cisar, Justin, Wang, Aihua, Wang, Chao-yuan, Tanner, Alexandra, Shaffer, Paul, Jacoby, Edgar, Kazmi, Faraz, Shukla, Neetu, Philippar, Ulrike, Attar, Ricardo M., Edwards, James P., Kuduk, Scott D.

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Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithe... von Kim, Hyun-Jung, Litzenburger, Beate C., Cui, Xiaojiang, Delgado, David A., Grabiner, Brian C., Lin, Xin, Lewis, Michael T., Gottardis, Marco M., Wong, Tai W., Attar, Ricardo M., Carboni, Joan M., Lee, Adrian V.

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Drug safety is a barrier to the discovery and development of new androgen receptor antagonists von Foster, William R., Car, Bruce D., Shi, Hong, Levesque, Paul C., Obermeier, Mary T., Gan, Jinping, Arezzo, Joseph C., Powlin, Stephanie S., Dinchuk, Joseph E., Balog, Aaron, Salvati, Mark E., Attar, Ricardo M., Gottardis, Marco M.

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Influence of the bispecific antibody IgG subclass on T cell redirection von Kapelski, Stephanie, Cleiren, Erna, Attar, Ricardo M, Philippar, Ulrike, Häsler, Julien, Chiu, Mark L

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A carboxylic acid isostere screen of the DHODH inhibitor Brequinar von DeRatt, Lindsey G., Christine Pietsch, E., Tanner, Alexandra, Shaffer, Paul, Jacoby, Edgar, Wang, Weixue, Kazmi, Faraz, Zhang, Xiaochun, Attar, Ricardo M., Edwards, James P., Kuduk, Scott D.

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HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924 von Haluska, Paul, Carboni, Joan M, TenEyck, Cynthia, Attar, Ricardo M, Hou, Xiaonan, Yu, Chunrong, Sagar, Malvika, Wong, Tai W, Gottardis, Marco M, Erlichman, Charles

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Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors von Ross-Macdonald, Petra, de Silva, Heshani, Guo, Qi, Xiao, Hong, Hung, Chen-Yi, Penhallow, Becky, Markwalder, Jay, He, Liqi, Attar, Ricardo M, Lin, Tai-an, Seitz, Steven, Tilford, Charles, Wardwell-Swanson, Judith, Jackson, Donald

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The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors von FEI HANG, GREET, Ann, LEE, Francis Y, GOTTARDIS, Marco M, CLARK, Edwin, HELMAN, Lee, ATTAR, Ricardo M, DONGRE, Ashok, CARBONIC, Joan M, HURLBURT, Warren, XIA HAN, HAFEZI, Rameh, WITTENBERG, Gayle M, REEVES, Karen, JIWEN CHEN, ROBINSON, Douglas, AIXIN LI

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In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417 von Haluska, Paul, Carboni, Joan M, Loegering, David A, Lee, Francis Y, Wittman, Mark, Saulnier, Mark G, Frennesson, David B, Kalli, Kimberly R, Conover, Cheryl A, Attar, Ricardo M, Kaufmann, Scott H, Gottardis, Marco, Erlichman, Charles

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Crystallographic Structures of the Ligand-Binding Domains of the Androgen Receptor and Its T877A Mutant Complexed with the Natural Agonist Dihydrotestosterone von Sack, John S., Kish, Kevin F., Wang, Chihuei, Attar, Ricardo M., Kiefer, Susan E., An, Yongmi, Wu, Ginger Y., Scheffler, Julie E., Salvati, Mark E., Krystek, Stanley R., Weinmann, Roberto, Einspahr, Howard M.

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[2.2.1]-Bicyclic sultams as potent androgen receptor antagonists von Shan, Weifang, Balog, Aaron, Nation, Andrew, Zhu, Xiao, Chen, Jing, Cvijic, Mary Ellen, Geng, Jieping, Rizzo, Cheryl A., Spires, Thomas, Attar, Ricardo M., Obermeier, Mary, Traeger, Sarah, Dai, Jun, Zhang, Yingru, Galella, Michael, Trainor, George, Vite, Gregory D., Gavai, Ashvinikumar V.

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Discovery of a 2,4-Disubstituted Pyrrolo[1,2-f][1,2,4]triazine Inhibitor (BMS-754807) of Insulin-like Growth Factor Receptor (IGF-1R) Kinase in Clinical Development von Wittman, Mark D, Carboni, Joan M, Yang, Zheng, Lee, Francis Y, Antman, Melissa, Attar, Ricardo, Balimane, Praveen, Chang, Chiehying, Chen, Cliff, Discenza, Lorell, Frennesson, David, Gottardis, Marco M, Greer, Ann, Hurlburt, Warren, Johnson, Walter, Langley, David R, Li, Aixin, Li, Jianqing, Liu, Peiying, Mastalerz, Harold, Mathur, Arvind, Menard, Krista, Patel, Karishma, Sack, John, Sang, Xiaopeng, Saulnier, Mark, Smith, Daniel, Stefanski, Kevin, Trainor, George, Velaparthi, Upender, Zhang, Guifen, Zimmermann, Kurt, Vyas, Dolatrai M

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The current state of preclinical prostate cancer animal models von Pienta, Kenneth J., Abate-Shen, Cory, Agus, David B., Attar, Ricardo M., Chung, Leland W.K., Greenberg, Norman M., Hahn, William C., Isaacs, John T., Navone, Nora M., Peehl, Donna M., Simons, Jonathon W., Solit, David B., Soule, Howard R., VanDyke, Terry A., Weber, Michael J., Wu, Lily, Vessella, Robert L.

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BMS-536924 Reverses IGF-IR-Induced Transformation of Mammary Epithelial Cells and Causes Growth Inhibition and Polarization of MCF7 Cells von Litzenburger, Beate C, Kim, Hyun-Jung, Kuiatse, Isere, Carboni, Joan M, Attar, Ricardo M, Gottardis, Marco M, Fairchild, Craig R, Lee, Adrian V

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Insulin Receptor (IR) Pathway Hyperactivity in IGF-IR Null Cells and Suppression of Downstream Growth Signaling Using the Dual IGF-IR/IR Inhibitor, BMS-754807 von Dinchuk, Joseph E, Cao, Carolyn, Huang, Fei, Reeves, Karen A, Wang, Jeanne, Myers, Fanny, Cantor, Glenn H, Zhou, Xiadi, Attar, Ricardo M, Gottardis, Marco, Carboni, Joan M

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Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer von ATTAR, Ricardo M, JURE-KUNKEL, Maria, WEIFANG SHAN, SALVATI, Mark E, FOSTER, William R, DINCHUK, Joseph, CHEN, Shen-Jue, VITE, Gregory, KRAMER, Robert, GOTTARDIS, Marco M, BALOG, Aaron, CVIJIC, Mary Ellen, DELL-JOHN, Janet, RIZZO, Cheryl A, SCHWEIZER, Liang, SPIRES, Thomas E, SUSO PLATERO, J, OBERMEIER, Mary

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