Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile von Futatsugi, K, Huard, K, Kung, D W, Pettersen, J C, Flynn, D A, Gosset, J R, Aspnes, G E, Barnes, R J, Cabral, S, Dowling, M S, Fernando, D P, Goosen, T C, Gorczyca, W P, Hepworth, D, Herr, M, Lavergne, S, Li, Q, Niosi, M, Orr, S T M, Pardo, I D, Perez, S M, Purkal, J, Schmahai, T J, Shirai, N, Shoieb, A M, Zhou, J, Goodwin, B

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Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profileAll authors were employed by Pfizer Inc. at th... von Futatsugi, K, Huard, K, Kung, D. W, Pettersen, J. C, Flynn, D. A, Gosset, J. R, Aspnes, G. E, Barnes, R. J, Cabral, S, Dowling, M. S, Fernando, D. P, Goosen, T. C, Gorczyca, W. P, Hepworth, D, Herr, M, Lavergne, S, Li, Q, Niosi, M, Orr, S. T. M, Pardo, I. D, Perez, S. M, Purkal, J, Schmahai, T. J, Shirai, N, Shoieb, A. M, Zhou, J, Goodwin, B

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Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile† †All authors were employed by Pfizer Inc. at... von Futatsugi, K., Huard, K., Kung, D. W., Pettersen, J. C., Flynn, D. A., Gosset, J. R., Aspnes, G. E., Barnes, R. J., Cabral, S., Dowling, M. S., Fernando, D. P., Goosen, T. C., Gorczyca, W. P., Hepworth, D., Herr, M., Lavergne, S., Li, Q., Niosi, M., Orr, S. T. M., Pardo, I. D., Perez, S. M., Purkal, J., Schmahai, T. J., Shirai, N., Shoieb, A. M., Zhou, J., Goodwin, B.

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Exciton-dominated Dielectric Function of Atomically Thin MoS2 Films von Yu, Yiling, Yu, Yifei, Cai, Yongqing, Li, Wei, Gurarslan, Alper, Peelaers, Hartwin, Aspnes, David E., Van de Walle, Chris G., Nguyen, Nhan V., Zhang, Yong-Wei, Cao, Linyou

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GLUCAGON RECEPTOR MODULATOR von ASPNES, GARY ERIK GE, FILIPSKI, KEVIN JAMES KJ, PFEFFERKORN, JEFFREY ALLEN JA, STEVENS, BENJAMIN DAWSON BD, LEE, ESTHER CHENG YIN ECY, DIDIUK, MARY THERESA MT, GUZMAN-PEREZ, ANGEL A, TU, MEIHUA MIKE MM

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Shallow acceptor complexes in p-type ZnO von Reynolds, J. G., Reynolds, C. L., Mohanta, A., Muth, J. F., Rowe, J. E., Everitt, H. O., Aspnes, D. E.

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Noise reduction and peak detection in x-ray diffraction data by linear and nonlinear methods von Le, Long V., Deijkers, Jeroen A., Kim, Young D., Wadley, Haydn N. G., Aspnes, David E.

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Combined direct- and reciprocal-space approach for converting spectra to energy scales with negligible loss of information von Aspnes, D.E., Choi, S.G.

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Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents von Londregan, Allyn T, Wei, Liuqing, Xiao, Jun, Lintner, Nathanael G, Petersen, Donna, Dullea, Robert G, McClure, Kim F, Bolt, Michael W, Warmus, Joseph S, Coffey, Steven B, Limberakis, Chris, Genovino, Julien, Thuma, Benjamin A, Hesp, Kevin D, Aspnes, Gary E, Reidich, Benjamin, Salatto, Christopher T, Chabot, Jeffrey R, Cate, Jamie H. D, Liras, Spiros, Piotrowski, David W

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Small molecule inhibitors of PCSK9. SAR investigations of head and amine groups von Aspnes, Gary E., Coffey, Steven B., Darout, Etzer, Dechert-Schmitt, Anne-Marie, Dullea, Robert G., Kamlet, Adam S., Limberakis, Chris, Londregan, Allyn T., McClure, Kim F., Menhaji-Klotz, Elnaz, Piotrowski, David W., Polivkova, Jana, Raymer, Brian, Ruggeri, Roger B., Salatto, Christopher T., Tu, Meihua, Wei, Liuqing, Xiao, Jun

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GLUCAGON RECEPTOR MODULATOR von ASPNES,GARY ERIK GE, LEE,ESTHER CHENG YIN ECY, DIDIUK,MARY THERESA MT, STEVENS,BENJAMIN DAWSON BD, GUZMAN-PEREZ,ANGEL A, PFEFFERKORN,JEFFREY ALLEN JA, FILIPSKI,KEVIN JAMES KJ, TU,MEIHUA MIKE MM

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Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5′-Adenosine Monophosphate-Activated Protein Kinase (AMPK) von Edmonds, David J, Kung, Daniel W, Kalgutkar, Amit S, Filipski, Kevin J, Ebner, David C, Cabral, Shawn, Smith, Aaron C, Aspnes, Gary E, Bhattacharya, Samit K, Borzilleri, Kris A, Brown, Janice A, Calabrese, Matthew F, Caspers, Nicole L, Cokorinos, Emily C, Conn, Edward L, Dowling, Matthew S, Eng, Heather, Feng, Bo, Fernando, Dilinie P, Genung, Nathan E, Herr, Michael, Kurumbail, Ravi G, Lavergne, Sophie Y, Lee, Esther C.-Y, Li, Qifang, Mathialagan, Sumathy, Miller, Russell A, Panteleev, Jane, Polivkova, Jana, Rajamohan, Francis, Reyes, Allan R, Salatto, Christopher T, Shavnya, Andre, Thuma, Benjamin A, Tu, Meihua, Ward, Jessica, Withka, Jane M, Xiao, Jun, Cameron, Kimberly O

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Evolution of the Synthesis of AMPK Activators for the Treatment of Diabetic Nephropathy: From Three Preclinical Candidates to the Investigational New Drug PF-06409577 von Smith, Aaron C, Kung, Daniel W, Shavnya, Andre, Brandt, Thomas A, Dent, Philip D, Genung, Nathan E, Cabral, Shawn, Panteleev, Jane, Herr, Michael, Yip, Ka Ning, Aspnes, Gary E, Conn, Edward L, Dowling, Matthew S, Edmonds, David J, Edmonds, Ian D, Fernando, Dilinie P, Herrinton, Paul M, Keene, Nandell F, Lavergne, Sophie Y, Li, Qifang, Polivkova, Jana, Rose, Colin R, Thuma, Benjamin A, Vetelino, Michael G, Wang, Guoqiang, Weaver, John D, Widlicka, Daniel W, Price Wiglesworth, Kristin E, Xiao, Jun, Zahn, Todd, Zhang, Yingxin

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Bond-specific reaction kinetics during the oxidation of (111) Si:Effect of n -type doping von Gokce, B., Aspnes, D. E., Lucovsky, G., Gundogdu, K.

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WHO-ISG collaboration on assistive technologies for healthy ageing-in-place: A round table discussion von Aspnes, E., Bergschold, J., Charness, N., Fang, M. L., Gutman, G., Hsu, Y., Kearns, W., Kort, H. S. M., Raymundo, T. M., Nap, H., Zandi, D., Zhang, W.

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Simplified bond-hyperpolarizability model of second harmonic generation von Powell, G. D., Wang, J.-F., Aspnes, D. E.

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Above-band-gap dielectric functions of ZnGeAs2: Ellipsometric measurements and quasiparticle self-consistent GW calculations von Choi, S. G., van Schilfgaarde, M., Aspnes, D. E., Norman, A. G., Olson, J. M., Peshek, T. J., Levi, D. H.

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Ellipsometric study of single-crystal γ -InSe from 1.5 to 9.2 eV von Choi, S. G., Aspnes, D. E., Fuchser, A. L., Martinez-Tomas, C., Sanjosé, V. Muñoz, Levi, D. H.

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Differences Between Charge Trapping States in Irradiated Nano-Crystalline HfO2 and Non-Crystalline Hf Silicates von Lucovsky, G, Fleetwood, D. M, Lee, S, Seo, H, Schrimpf, R. D, Felix, J. A, Lning, J, Fleming, L. B, Ulrich, M, Aspnes, D. E

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Dielectric properties of InAsP alloy thin films and evaluation of direct- and reciprocal-space methods of determining critical-point parameters von Choi, S. G., Aspnes, D. E., Stoute, N. A., Kim, Y. D., Kim, H. J., Chang, Y.-C., Palmstrøm, C. J.

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