APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids von Zhao, Jing, Fu, Yuan, Yamazaki, Yu, Ren, Yingxue, Davis, Mary D., Liu, Chia-Chen, Lu, Wenyan, Wang, Xue, Chen, Kai, Cherukuri, Yesesri, Jia, Lin, Martens, Yuka A., Job, Lucy, Shue, Francis, Nguyen, Thanh Thanh, Younkin, Steven G., Graff-Radford, Neill R., Wszolek, Zbigniew K., Brafman, David A., Asmann, Yan W., Ertekin-Taner, Nilüfer, Kanekiyo, Takahisa, Bu, Guojun

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Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways von Zhao, Na, Ren, Yingxue, Yamazaki, Yu, Qiao, Wenhui, Li, Fuyao, Felton, Lindsey M., Mahmoudiandehkordi, Siamak, Kueider-Paisley, Alexandra, Sonoustoun, Berkiye, Arnold, Matthias, Shue, Francis, Zheng, Jiaying, Attrebi, Olivia N., Martens, Yuka A., Li, Zonghua, Bastea, Ligia, Meneses, Axel D., Chen, Kai, Thompson, J. Will, St John-Williams, Lisa, Tachibana, Masaya, Aikawa, Tomonori, Oue, Hiroshi, Job, Lucy, Yamazaki, Akari, Liu, Chia-Chen, Storz, Peter, Asmann, Yan W., Ertekin-Taner, Nilüfer, Kanekiyo, Takahisa, Kaddurah-Daouk, Rima, Bu, Guojun

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ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components von Yamazaki, Yu, Shinohara, Mitsuru, Yamazaki, Akari, Ren, Yingxue, Asmann, Yan W., Kanekiyo, Takahisa, Bu, Guojun

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Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight von Ebbert, Mark T W, Jensen, Tanner D, Jansen-West, Karen, Sens, Jonathon P, Reddy, Joseph S, Ridge, Perry G, Kauwe, John S K, Belzil, Veronique, Pregent, Luc, Carrasquillo, Minerva M, Keene, Dirk, Larson, Eric, Crane, Paul, Asmann, Yan W, Ertekin-Taner, Nilufer, Younkin, Steven G, Ross, Owen A, Rademakers, Rosa, Petrucelli, Leonard, Fryer, John D

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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing von Lohr, Jens G, Stojanov, Petar, Lawrence, Michael S, Auclair, Daniel, Chapuy, Bjoern, Sougnez, Carrie, Cruz-Gordillo, Peter, Knoechel, Birgit, Asmann, Yan W, Slager, Susan L, Novak, Anne J, Dogan, Ahmet, Ansell, Stephen M, Link, Brian K, Zou, Lihua, Gould, Joshua, Saksena, Gordon, Stransky, Nicolas, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Hernández-Lemus, Enrique, Schwarz-Cruz y Celis, Angela, Imaz-Rosshandler, Ivan, Ojesina, Akinyemi I, Jung, Joonil, Pedamallu, Chandra S, Lander, Eric S, Habermann, Thomas M, Cerhan, James R, Shipp, Margaret A, Getz, Gad, Golub, Todd R

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Network approaches for omics studies of neurodegenerative diseases von Zhao, Na, Quicksall, Zachary, Asmann, Yan W., Ren, Yingxue

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Chronic Caloric Restriction Preserves Mitochondrial Function in Senescence without Increasing Mitochondrial Biogenesis von Lanza, Ian R., Zabielski, Piotrek, Klaus, Katherine A., Morse, Dawn M., Heppelmann, Carrie J., Bergen, H. Robert, Dasari, Surendra, Walrand, Stephane, Short, Kevin R., Johnson, Matthew L., Robinson, Matthew M., Schimke, Jill M., Jakaitis, Daniel R., Asmann, Yan W., Sun, Zhifu, Nair, K. Sreekumaran

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Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas von Braggio, Esteban, Van Wier, Scott, Ojha, Juhi, McPhail, Ellen, Asmann, Yan W, Egan, Jan, da Silva, Jackline Ayres, Schiff, David, Lopes, M Beatriz, Decker, Paul A, Valdez, Riccardo, Tibes, Raoul, Eckloff, Bruce, Witzig, Thomas E, Stewart, A Keith, Fonseca, Rafael, O'Neill, Brian Patrick

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Somatic selection distinguishes oncogenes and tumor suppressor genes von Chandrashekar, Pramod, Ahmadinejad, Navid, Wang, Junwen, Sekulic, Aleksandar, Egan, Jan B, Asmann, Yan W, Kumar, Sudhir, Maley, Carlo, Liu, Li

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Assessment and Optimization of Explainable Machine Learning Models Applied to Transcriptomic Data von Zhao, Yongbing, Shao, Jinfeng, Asmann, Yan W.

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ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain von Aikawa, Tomonori, Ren, Yingxue, Yamazaki, Yu, Tachibana, Masaya, Johnson, Madeleine R., Anderson, Casey T., Martens, Yuka A., Holm, Marie-Louise, Asmann, Yan W., Saito, Takashi, Saido, Takaomi C., Fitzgerald, Michael L., Bu, Guojun, Kanekiyo, Takahisa

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IAP antagonists induce anti-tumor immunity in multiple myeloma von Chesi, Marta, Mirza, Noweeda N, Garbitt, Victoria M, Sharik, Meaghen E, Dueck, Amylou C, Asmann, Yan W, Akhmetzyanova, Ilseyar, Kosiorek, Heidi E, Calcinotto, Arianna, Riggs, Daniel L, Keane, Niamh, Ahmann, Gregory J, Morrison, Kevin M, Fonseca, Rafael, Lacy, Martha Q, Dingli, David, Kumar, Shaji K, Ailawadhi, Sikander, Dispenzieri, Angela, Buadi, Francis, Gertz, Morie A, Reeder, Craig B, Lin, Yi, Chanan-Khan, Asher A, Stewart, A Keith, Fooksman, David, Bergsagel, P Leif

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NucMap: a database of genome-wide nucleosome positioning map across species von Zhao, Yongbing, Wang, Jinyue, Liang, Fang, Liu, Yanxia, Wang, Qi, Zhang, Hao, Jiang, Meiye, Zhang, Zhewen, Zhao, Wenming, Bao, Yiming, Zhang, Zhang, Wu, Jiayan, Asmann, Yan W, Li, Rujiao, Xiao, Jingfa

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Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease von Crist, Angela M., Hinkle, Kelly M., Wang, Xue, Moloney, Christina M., Matchett, Billie J., Labuzan, Sydney A., Frankenhauser, Isabelle, Azu, Nkem O., Liesinger, Amanda M., Lesser, Elizabeth R., Serie, Daniel J., Quicksall, Zachary S., Patel, Tulsi A., Carnwath, Troy P., DeTure, Michael, Tang, Xiaojia, Petersen, Ronald C., Duara, Ranjan, Graff-Radford, Neill R., Allen, Mariet, Carrasquillo, Minerva M., Li, Hu, Ross, Owen A., Ertekin-Taner, Nilüfer, Dickson, Dennis W., Asmann, Yan W., Carter, Rickey E., Murray, Melissa E.

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MicroRNA networks in mouse lung organogenesis von Dong, Jie, Jiang, Guoqian, Asmann, Yan W, Tomaszek, Sandra, Jen, Jin, Kislinger, Thomas, Wigle, Dennis A

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Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain von Ren, Yingxue, Wang, Xue, Zhang, Shuwen, Hu, Hongru, Quicksall, Zachary, Lee, Sangderk, Morganti, Josh M., Johnson, Lance A., Asmann, Yan W., Zhao, Na

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TYROBP genetic variants in early-onset Alzheimer's disease von Pottier, Cyril, Ravenscroft, Thomas A, Brown, Patricia H, Finch, NiCole A, Baker, Matt, Parsons, Meeia, Asmann, Yan W, Ren, Yingxue, Christopher, Elizabeth, Levitch, Denise, van Blitterswijk, Marka, Cruchaga, Carlos, Campion, Dominique, Nicolas, Gaël, Richard, Anne-Claire, Guerreiro, Rita, Bras, Jose T, Zuchner, Stephan, Gonzalez, Michael A, Bu, Guojun, Younkin, Steven, Knopman, David S, Josephs, Keith A, Parisi, Joseph E, Petersen, Ronald C, Ertekin-Taner, Nilüfer, Graff-Radford, Neill R, Boeve, Bradley F, Dickson, Dennis W, Rademakers, Rosa

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3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer von Asmann, Yan W, Klee, Eric W, Thompson, E Aubrey, Perez, Edith A, Middha, Sumit, Oberg, Ann L, Therneau, Terry M, Smith, David I, Poland, Gregory A, Wieben, Eric D, Kocher, Jean-Pierre A

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Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases von Allen, Mariet, Wang, Xue, Burgess, Jeremy D., Watzlawik, Jens, Serie, Daniel J., Younkin, Curtis S., Nguyen, Thuy, Malphrus, Kimberly G., Lincoln, Sarah, Carrasquillo, Minerva M., Ho, Charlotte, Chakrabarty, Paramita, Strickland, Samantha, Murray, Melissa E., Swarup, Vivek, Geschwind, Daniel H., Seyfried, Nicholas T., Dammer, Eric B., Lah, James J., Levey, Allan I., Golde, Todd E., Funk, Cory, Li, Hongdong, Price, Nathan D., Petersen, Ronald C., Graff-Radford, Neill R., Younkin, Steven G., Dickson, Dennis W., Crook, Julia R., Asmann, Yan W., Ertekin-Taner, Nilüfer

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Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer von Necela, Brian M, Carr, Jennifer M, Asmann, Yan W, Thompson, E Aubrey

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