Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases von Caldwell, Richard D, Qiu, Hui, Askew, Ben C, Bender, Andrew T, Brugger, Nadia, Camps, Montserrat, Dhanabal, Mohanraj, Dutt, Vikram, Eichhorn, Thomas, Gardberg, Anna S, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Healey, Brian, Hodous, Brian L, Huck, Bayard R, Johnson, Theresa L, Jones, Christopher, Jones, Reinaldo C, Mochalkin, Igor, Morandi, Federica, Nguyen, Ngan, Meyring, Michael, Potnick, Justin R, Santos, Dusica Cvetinovic, Schmidt, Ralf, Sherer, Brian, Shutes, Adam, Urbahns, Klaus, Follis, Ariele Viacava, Wegener, Ansgar A, Zimmerli, Simone C, Liu-Bujalski, Lesley

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Ocular Distribution and Pharmacodynamics of SF0166, a Topically Administered α v β 3 Integrin Antagonist, for the Treatment of Retinal Diseases von Askew, Ben C, Furuya, Takeru, Edwards, D Scott

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11β-Hydroxysteroid dehydrogenase-1 as a therapeutic target for metabolic diseases von Fotsch, Christopher, Askew, Ben C, Chen, Jian Jeffrey

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Ocular Distribution and Pharmacodynamics of SF0166, a Topically Administered αvβ3 Integrin Antagonist, for the Treatment of Retinal Diseases von Askew, Ben C, Furuya, Takeru, Edwards, D Scott

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Nonpeptide α vβ 3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone von Whitman, David B., Askew, Ben C., Duong, Le T., Fernandez-Metzler, Carmen, Halczenko, Wasyl, Hartman, George D., Hutchinson, John H., Leu, Chih-Tai, Prueksaritanont, Thomayant, Rodan, Gideon A., Rodan, Sevgi B., Duggan, Mark E.

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Non-peptide αvβ3 antagonists. Part 3: Identification of potent RGD mimetics incorporating novel β-amino acids as aspartic acid replacements von COLEMAN, Paul J, BRASHEAR, Karen M, RODAN, Gideon A, LEU, Chih-Tai, PRUEKSARITANONT, Thomayant, FERNANDEZ-METZLER, Carmen, MA, Bennett, LIBBY, Laura A, MERKLE, Kara M, STUMP, Gary L, WALLACE, Audrey A, LYNCH, Joseph J, HUNT, Cecilia A, LYNCH, Robert, DUGGAN, Mark E, HOFFMAN, William F, HUTCHINSON, John H, BRESLIN, Michael J, MCVEAN, Carol A, ASKEW, Ben C, HARTMAN, George D, RODAN, Sevgi B

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Nonpeptide αvβ3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone von WHITMAN, David B, ASKEW, Ben C, RODAN, Sevgi B, DUGGAN, Mark E, DUONG, Le T, FERNANDEZ-METZLER, Carmen, HALCZENKO, Wasyl, HARTMAN, George D, HUTCHINSON, John H, LEU, Chih-Tai, PRUEKSARITANONT, Thomayant, RODAN, Gideon A

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Nonpeptide αvβ3 Antagonists. Part 11:  Discovery and Preclinical Evaluation of Potent αvβ3 Antagonists for the Prevention and Treatment of Osteoporosis von Coleman, Paul J, Brashear, Karen M, Askew, Ben C, Hutchinson, John H, McVean, Carol A, Duong, Le T, Feuston, Bradley P, Fernandez-Metzler, Carmen, Gentile, Michael A, Hartman, George D, Kimmel, Donald B, Leu, Chih-Tai, Lipfert, Lorraine, Merkle, Kara, Pennypacker, Brenda, Prueksaritanont, Thomayant, Rodan, Gideon A, Wesolowski, Gregg A, Rodan, Sevgi B, Duggan, Mark E

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Discovery and evaluation of dual CDK1 and CDK2 inhibitors von PAYTON, Marc, CHUNG, Grace, ASKEW, Ben, TASKER, Andrew, RADINSKY, Robert, KENDALL, Richard, COATS, Steve, YAKOWEC, Peter, WONG, Andrew, POWERS, Dave, LING XIONG, ZHANG, Nancy, LEAL, Juan, BUSH, Tammy L, SANTORA, Vincent

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SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors von Karra, Srinivasa, Xiao, Yufang, Chen, Xiaoling, Liu-Bujalski, Lesley, Huck, Bayard, Sutton, Amanda, Goutopoulos, Andreas, Askew, Ben, Josephson, Kristopher, Jiang, Xuliang, Shutes, Adam, Shankar, Vikram, Noonan, Tom, Garcia-Berrios, Gaianne, Dong, Rong, Dhanabal, Mohanraj, Tian, Hui, Wang, Zhenxiong, Clark, A., Goodstal, Samantha

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STABLE OPHTHALMIC FORMULATIONS OF A FLUORINATED INTEGRIN ANTAGONIST von EDWARDS, D, ASKEW, Ben

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The discovery of 2-anilinothiazolones as 11β-HSD1 inhibitors von Yuan, Chester, St. Jean, David J., Liu, Qingyian, Cai, Lynn, Li, Aiwen, Han, Nianhe, Moniz, George, Askew, Ben, Hungate, Randall W., Johansson, Lars, Tedenborg, Lars, Pyring, David, Williams, Meredith, Hale, Clarence, Chen, Michelle, Cupples, Rod, Zhang, Jiandong, Jordan, Steven, Bartberger, Michael D., Sun, Yaxiong, Emery, Maurice, Wang, Minghan, Fotsch, Christopher

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Convergent functional groups: synthetic and structural studies von Rebek, Julius, Marshall, Luann, Wolak, Raymond, Parris, Kevin, Killoran, Mary, Askew, Ben, Nemeth, David, Islam, N

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FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF von ASKEW, Ben C, FURUYA, Takeru

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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or rest... von Egbertson, Melissa S, Bednar, Bohumil, Askew, Ben C, Bednar, Rodney A, Brashear, Karen, Breslin, Michael J, Duggan, Mark E, Fisher, Thorsten E, Halczenko, Wasyl, Hutchinson, John H, Ihle, Nathan, Prugh, John D, Wai, John S, Gould, Robert J, Hartman, George D

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FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF von FURUYA, TAKERU, ASKEW, BEN C

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Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof von Askew, Ben C, Furuya, Takeru

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FLUORINATED DERIVATIVES OF 3-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)IMIDAZOLIDIN-1-YL)PROPANOIC ACID AND USES THEREOF von ASKEW, Ben C, FURUYA, Takeru

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FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF von ASKEW, Ben C, FURUYA, Takeru

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FLUORINATED DERIVATIVES OF 3-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)IMIDAZOLIDIN-1-YL)PROPANOIC ACID AND USES THEREOF von ASKEW, Ben, C, FURUYA, Takeru

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