TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production von Lenert, Petar, Brummel, Rachel, Field, Elizabeth H, Ashman, Robert F

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Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding von Ashman, Robert F, Goeken, J Adam, Latz, Eicke, Lenert, Petar

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Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells von Stunz, Laura L., Lenert, Petar, Peckham, David, Yi, Ae‐Kyung, Haxhinasto, Sokol, Chang, Ming, Krieg, Arthur M., Ashman, Robert F.

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CpG Oligodeoxyribonucleotides Rescue Mature Spleen B Cells from Spontaneous Apoptosis and Promote Cell Cycle Entry von Yi, Ae-Kyung, Chang, Ming, Peckham, David W, Krieg, Arthur M, Ashman, Robert F

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Sequence requirements for oligodeoxyribonucleotide inhibitory activity von Ashman, Robert F., Goeken, J. Adam, Drahos, Jennifer, Lenert, Petar

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Extended sequence preferences for oligodeoxyribonucleotide activity von Lenert, Petar, Goeken, Adam J., Ashman, Robert F.

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DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-... von Lenert, Petar, Yasuda, Kei, Busconi, Liliana, Nelson, Patrice, Fleenor, Courtney, Ratnabalasuriar, Radhika S, Nagy, Peter L, Ashman, Robert F, Rifkin, Ian R, Marshak-Rothstein, Ann

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Aggregation and secondary loop structure of oligonucleotides do not determine their ability to inhibit TLR9 von Ashman, Robert F., Goeken, J. Adam, Lenert, Petar S.

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Structural requirements and applications of inhibitory oligodeoxyribonucleotides von Ashman, Robert F, Lenert, Petar

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Difference in apoptosis induction between surface IgD and IgM von Peckham, David, Andersen-Nissen, Erica, Finkelman, Fred D., Stunz, Laura L., Ashman, Robert F.

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Structural characterization of the inhibitory DNA motif for the type A (D)-CpG-induced cytokine secretion and NK-cell lytic activity in mouse spleen cells von Lenert, Petar, Rasmussen, Wendy, Ashman, Robert F, Ballas, Zuhair K

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CpG DNA rescues B cells from apoptosis by activating NFκB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway von Yi, Ae-Kyung, Peckham, Dave W., Ashman, Robert F., Krieg, Arthur M.

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Innate immune responses in lupus-prone Palmerston North mice: Differential responses to LPS and bacterial DNA/CpG oligonucleotides von LENERT, Petar, GOEKEN, Adam, HANDWERGER, Barry S, ASHMAN, Robert F

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Safety and In Vivo Efficacy of Innate (Class R) and Broadly Reactive (Class B) Inhibitory Oligonucleotides (INH-ODN) in MRL-Fas/lpr Lupus Mice von Lenert, Petar, Assistant Professor, Department of Internal Medicine, The University of Iowa, Iowa City, IA, Seyfer, Sarah, BS, Internal Medicine, Iowa City, IA, Pareigis, Elizabeth R., BS, Internal Medicine, The University of Iowa, Iowa City, IA, Ashman, Robert F., Professor, Internal Medicine, The University of Iowa, Iowa City, IA

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Inhibitory oligonucleotide (IN-ODN) structure-function relationships: species and backbone differences (131.19) von Ashman, Robert F., Goeken, Adam, Lenert, Petar

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DNA‐like prototypic INH‐ODNs selectively inhibit B cell receptor for antigen (BCR) triggered TLR9 activation in autoimmune B cells von Lenert, Petar, Ratnabalasuriar, Radhika S., Fleenor, Courtney J., Ashman, Robert F., Marshak‐Rothstein, Ann

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Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4 von Illera, VA, Perandones, CE, Stunz, LL, Mower, DA, Jr, Ashman, RF

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Fc receptor off-signal in the B cell involves apoptosis von Ashman, RF, Peckham, D, Stunz, LL

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In vivo therapeutic potential of classes B and R inhibitory oligonucleotides (INH-ODH) for animal lupus (131.18) von Lenert, Petar, Pareigis, Elizabeth R., Seyfer, Sarah, Lawry, Molly, Ashman, Robert F.

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Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis von Mower, DA, Jr, Peckham, DW, Illera, VA, Fishbaugh, JK, Stunz, LL, Ashman, RF

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