Neprilysin Is Suppressed by Dual-Specificity Tyrosine-Phosphorylation Regulated Kinase 1A (DYRK1A) in Down-Syndrome-Derived Fibroblasts von Kawakubo, Takashi, Mori, Ryotaro, Shirotani, Keiro, Iwata, Nobuhisa, Asai, Masashi

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Paradigm shift from diagnosing patients based on common symptoms to categorizing patients into subtypes with different pathogenic mechanisms to guide treatment for Alzheimer's dise... von Shirotani, Keiro, Asai, Masashi, Iwata, Nobuhisa

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Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice von Iwata, Nobuhisa, Sekiguchi, Misaki, Hattori, Yoshino, Takahashi, Akane, Asai, Masashi, Ji, Bin, Higuchi, Makoto, Staufenbiel, Matthias, Muramatsu, Shin-ichi, Saido, Takaomi C.

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Cathepsin K-mediated notch1 activation contributes to neovascularization in response to hypoxia von Jiang, Haiying, Wu Cheng, Xian, Shi, Guo-Ping, Hu, Lina, Inoue, Aiko, Yamamura, Yumiko, Wu, Hongxian, Takeshita, Kyosuke, Li, Xiang, Huang, Zhe, Song, Haizhen, Asai, Masashi, Hao, Chang-Ning, Unno, Kazumasa, Koike, Teruhiro, Oshida, Yoshiharu, Okumura, Kenji, Murohara, Toyoaki, Kuzuya, Masafumi

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Perturbed Calcineurin-NFAT Signaling Is Associated with the Development of Alzheimer’s Disease von Asai, Masashi, Kinjo, Aimi, Kimura, Shoko, Mori, Ryotaro, Kawakubo, Takashi, Shirotani, Keiro, Yagishita, Sosuke, Maruyama, Kei, Iwata, Nobuhisa

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Characterization of the human zinc finger nfx‑1‑type containing 1 encoding ZNFX1 gene and its response to 12‑O‑tetradecanoyl‑13‑acetate in HL‑60 cells von Hamada, Hiroshi, Yamamura, Mayu, Ohi, Hiroto, Kobayashi, Yota, Niwa, Kuniyoshi, Oyama, Takahiro, Mano, Yasunari, Asai, Masashi, Tanuma, Sei-Ichi, Uchiumi, Fumiaki

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Characterization of the human IDH1 gene promoter von Takihara, Yutaka, Otani, Ryuji, Ishii, Takuro, Takaoka, Shunsuke, Nakano, Yuki, Inoue, Kaori, Larsen, Steven, Ogino, Yoko, Asai, Masashi, Tanuma, Sei-ichi, Uchiumi, Fumiaki

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Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness von Kondo, Takayuki, Asai, Masashi, Tsukita, Kayoko, Kutoku, Yumiko, Ohsawa, Yutaka, Sunada, Yoshihide, Imamura, Keiko, Egawa, Naohiro, Yahata, Naoki, Okita, Keisuke, Takahashi, Kazutoshi, Asaka, Isao, Aoi, Takashi, Watanabe, Akira, Watanabe, Kaori, Kadoya, Chie, Nakano, Rie, Watanabe, Dai, Maruyama, Kei, Hori, Osamu, Hibino, Satoshi, Choshi, Tominari, Nakahata, Tatsutoshi, Hioki, Hiroyuki, Kaneko, Takeshi, Naitoh, Motoko, Yoshikawa, Katsuhiro, Yamawaki, Satoko, Suzuki, Shigehiko, Hata, Ryuji, Ueno, Shu-ichi, Seki, Tsuneyoshi, Kobayashi, Kazuhiro, Toda, Tatsushi, Murakami, Kazuma, Irie, Kazuhiro, Klein, William L., Mori, Hiroshi, Asada, Takashi, Takahashi, Ryosuke, Iwata, Nobuhisa, Yamanaka, Shinya, Inoue, Haruhisa

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ダウン症患者における早期アルツハイマー病発症メカニズムの解明 von 浅井, 将, 川久保, 昂, 森, 亮太郎, 岩田, 修永

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Elucidating Pathogenic Mechanisms of Early-onset Alzheimer's Disease in Down Syndrome Patients von Asai, Masashi, Kawakubo, Takashi, Mori, Ryotaro, Iwata, Nobuhisa

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Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase von Asai, Masashi, Hattori, Chinatsu, Szabó, Beáta, Sasagawa, Noboru, Maruyama, Kei, Tanuma, Sei-ichi, Ishiura, Shoichi

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The novel β‐secretase inhibitor KMI‐429 reduces amyloid β peptide production in amyloid precursor protein transgenic and wild‐type mice von Asai, Masashi, Hattori, Chinatsu, Iwata, Nobuhisa, Saido, Takaomi C., Sasagawa, Noboru, Szabó, Beáta, Hashimoto, Yasuhiro, Maruyama, Kei, Tanuma, Sei‐ichi, Kiso, Yoshiaki, Ishiura, Shoichi

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Gurdjieff as a Source of Transpersonal Psychologies von ASAI, MASASHI

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BACE1 interacts with lipid raft proteins von Hattori, Chinatsu, Asai, Masashi, Onishi, Hayato, Sasagawa, Noboru, Hashimoto, Yasuhiro, Saido, Takaomi C., Maruyama, Kei, Mizutani, Shigehiko, Ishiura, Shoichi

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PT579. Disease-modifying therapy through enhancement of neuronal Aß-degrading enzyme neprilysin activity for Alzheimer’s disease von Iwata, Nobuhisa, Asai, Masashi, Hatta, Daisuke, Honda, Mikako, Hori, Yuma, Kinoshita, Momoka, Kuroda, Naotaka, Ohyama, Kaname, Shirotani, Keiro, Tanaka, Takashi, Watanabe, Kaori

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Putative function of ADAM9, ADAM10, and ADAM17 as APP [formula omitted]-secretase von Asai, Masashi, Hattori, Chinatsu, Szabó, Beáta, Sasagawa, Noboru, Maruyama, Kei, Tanuma, Sei-ichi, Ishiura, Shoichi

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Yuriko Noguchi, Lawrence and Murdoch: Paternal Intellect and Maternal Love von Asai, Masashi

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P1–091: Modeling Alzheimer's disease using induced pluripotent stem cells from familial and sporadic Alzheimer's disease patients von Shirotani, Keiro, Kondo, Takayuki, Asai, Masashi, Tsukita, Kayoko, Watanabe, Kaori, Maruyama, Kei, Murakami, Kazuma, Irie, Kazuhiro, Klein, William, Mori, Hiroshi, Asada, Takash, Inoue, Haruhisa, Iwata, Nobuhisa

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Modeling Alzheimer's disease using induced pluripotent stem cells from familial and sporadic Alzheimer's disease patients von Shirotani, Keiro, Kondo, Takayuki, Asai, Masashi, Tsukita, Kayoko, Watanabe, Kaori, Maruyama, Kei, Murakami, Kazuma, Irie, Kazuhiro, Klein, William, Mori, Hiroshi, Asada, Takash, Inoue, Haruhisa, Iwata, Nobuhisa

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Modeling Alzheimer's disease using iPS cells reveals stress phenotypes associated with intracellular beta-amyloid oligomer and differential drug responsiveness von Asai, Masashi, Kondo, Takayuki, Shirotani, Keiro, Tsukita, Kayoko, Watanabe, Kaori, Maruyama, Kei, Murakami, Kazuma, Irie, Kazuhiro, Klein, William, Mori, Hiroshi, Asada, Takash, Inoue, Haruhisa, Iwata, Nobuhisa

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