EPIC: an evaluation of the psychological impact of early-phase clinical trials in cancer patients von Jittla, P., Graham, D.M., Zhou, C., Halliwell, J., O’Reilly, S., Aruketty, S., Azizi, A., Germetaki, T., Lowe, J., Little, M., Punnett, G., McMahon, P., Benson, L., Carter, L., Krebs, M.G., Thistlethwaite, F.C., Darlington, E., Yorke, J., Cook, N.

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1849P Ethnicity and socioeconomic deprivation in early phase clinical trials in a UK tertiary referral centre von Billy Graham Mariam, N., Rahman, R., Mistry, H., Aruketty, S., Adamson-Raieste, A., Church, M., Scott, J-A., Carter, L., Thistlethwaite, F., Krebs, M.G., Cook, N., Graham, D.

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44P Value of comprehensive genomic profiling in pre-screening patients for NTRK fusion in STARTRK2 trial: Single centre experience von Ortega Franco, A., Adamson-Raieste, A., Rahman, R., Pihlak, R., Peters, N., Scott, J-A., Aruketty, S., Thomson, C., Dransfield, S., Henshaw, A., Ward, A., Cutts, T., Carter, L., Thistlethwaite, F., Cook, N., Graham, D.M., Stevenson, J., Krebs, M.G.

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1493P An evaluation of the psychological impact of early phase clinical trials in cancer patients von Jittla, P., Graham, D., Zhou, C., Halliwell, J., O'Reilly, S., Aruketty, S., Azizi, A., Germetaki, T., Lowe, J., Little, M., Punnett, G., McMahon, P., Benson, L., Carter, L., Krebs, M.G., Thistlethwaite, F., Yorke, J., Cook, N.

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Enhanced supportive care in early phase clinical trials von Cook, N., Carter, L., Aruketty, S., O'Brien, C., Thistlethwaite, F., Dean, E., Krebs, M., Warren, M., Berman, R.

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Development of the Manchester Cancer Research Centre Molecular Tumour Board for matching patients to clinical trials based on tumour and ctDNA genetic profiling von Gupta, A., Ayub, M., Miller, C., Rothwell, D., Wallace, A., Jordan, A., Cook, N., Thistlethwaite, F., Carter, L., O’Brien, C., Aruketty, S., Dean, E., Hudson, A., Frese, K., Dransfield, J., Hughes, A., Marais, R., Dive, C., Brady, G., Krebs, M.

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P2.13-33 A Case Report of Exceptional Clinical Response to MEK Inhibition in a Patient with NRAS Mutation Positive NSCLC von Krebs, M., Graham, D., Ayub, M., Dransfield, J., Frost, H., Aruketty, S., Kilerci, B., Wallace, A., Kamboj, R., Bakhle, D., Palle, V., Sharma, S., Maharaj, N., Kumawat, R., Bhonde, M., Frese, K., Dive, C., Rothwell, D., Brady, G.

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Utility of ctDNA to support patient selection for early phase clinical trials: The TARGET Study von Rothwell, Dominic, Ayub, Mahmood, Cook, Natalie, Thistlethwaite, Fiona, Carter, L, Dean, Emma, Smith, N, Villa, S, Dransfield, J, Clipson, A, White, D, Nessa, K, Ferdous, Saba, Howell, Matthew, Gupta, A, Kilerci, B, Mohan, S, Frese, K, Gulati, S, Miller, C, Jordan, A, Eaton, H, Hickson, N, O'Brien, C, Graham, D, Kelly, C, Aruketty, S, Metcalf, R, Chiramel, J, Tinsley, Nadina, Vickers, AJ, Kurup, Roopa, Frost, H, Stevenson, J, Southam, S, Landers, Dónal, Wallace, A, Marais, Richard, Hughes, AM, Brady, G, Dive, Caroline, Krebs, Matthew

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P1.01-26 Single-Centre Experience of Clinical Outcomes for Advanced Lung Cancer Patients in Phase I Clinical Trials von Graham, D., Jordan, T., Tinsley, N., Aruketty, S., Vickers, A., Kelly, C., Kurup, R., White, A., Smith, A., Walsh, A., Thomson, C., O'Reilly, S., Norfolk, M., Chang, D., Blackhall, F., Summers, Y., Califano, R., Taylor, P., Thistlethwaite, F., Cook, N., Carter, L., Krebs, M.

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Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study von Rothwell, Dominic G., Ayub, Mahmood, Cook, Natalie, Thistlethwaite, Fiona, Carter, Louise, Dean, Emma, Smith, Nigel, Villa, Shaun, Dransfield, Joanne, Clipson, Alexandra, White, Daniel, Nessa, Kamrun, Ferdous, Saba, Howell, Matthew, Gupta, Avinash, Kilerci, Bedirhan, Mohan, Sumitra, Frese, Kris, Gulati, Sakshi, Miller, Crispin, Jordan, Allan, Eaton, Helen, Hickson, Nicholas, O’Brien, Ciara, Graham, Donna, Kelly, Claire, Aruketty, Sreeja, Metcalf, Robert, Chiramel, Jaseela, Tinsley, Nadina, Vickers, Alexander J., Kurup, Roopa, Frost, Hannah, Stevenson, Julie, Southam, Siobhan, Landers, Dónal, Wallace, Andrew, Marais, Richard, Hughes, Andrew M., Brady, Ged, Dive, Caroline, Krebs, Matthew G.

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Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells von Aruketty, Maneesha, Kurinna, Svitlana

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Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells von Aruketty, Maneesha, Kurinna, Svitlana

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Twelve tips to organise a mock OSCE von Gilani, Syed, Pankhania, Kishan, Aruketty, Maneesha, Naeem, Farah, Alkhayyat, Abdulaziz, Akhtar, Usmaan, Chaudhary, Muhammad, Sinha, Siddharth

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Release of miR-29 Target Laminin C2 Improves Skin Repair von Robinson, Connor J, Thiagarajan, Lalitha, Maynard, Rebecca, Aruketty, Maneesha, Herrera, Jeremy, Dingle, Lewis, Reid, Adam, Wong, Jason, Cao, Heng, Dooley, James, Liston, Adrian, Müllhaupt, Daniela, Hiebert, Paul, Hiebert, Hayley, Kurinna, Svitlana

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Differential response rates in early-phase cancer clinical trials (EPCCT) von Abdul Rahman, Rozana, Billy Graham Mariam, Neethu, Mistry, Hitesh, Aruketty, Sreeja, Church, Matt, Adamson-Raieste, Aidi, Scott, Julie-Anne, Thistlethwaite, Fiona, Krebs, Matthew, Carter, Louise, Graham, Donna M., Cook, Natalie

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The TARGET trial: Molecular profiling of circulating tumour DNA to stratify patients to early phase clinical trials von Rothwell, Dominic, Ayub, Mahmood, Gulati, Sakshi, Brognard, John, Wallace, Andrew, Miller, Crispin, Dean, Emma J, Cook, Natalie, Thistlethwaite, Fiona, Leong, Hui Sun, Eaton, Helen, Howard, Emma, Hudson, Andrew, Siswick, Carla, Dransfield, Joanne, Christodolou, Marianna, Smith, Nigel, Carter, Louise, Metcalf, Robert, Aruketty, Sreeja, Chiramel, Jaseela, Hughes, Andrew, Marais, Richard, Dive, Caroline, Brady, Ged, Krebs, Matthew G

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