Preclinical evaluation of statins as a treatment for ovarian cancer von Robinson, Elizabeth, Nandi, Mandrita, Wilkinson, Laurelle L, Arrowsmith, D. Mark, Curtis, Anthony D.M, Richardson, Alan

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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells von Park, Nicole I., Guilhamon, Paul, Desai, Kinjal, McAdam, Rochelle F., Langille, Ellen, O’Connor, Madlen, Lan, Xiaoyang, Whetstone, Heather, Coutinho, Fiona J., Vanner, Robert J., Ling, Erick, Prinos, Panagiotis, Lee, Lilian, Selvadurai, Hayden, Atwal, Gurnit, Kushida, Michelle, Clarke, Ian D., Voisin, Veronique, Cusimano, Michael D., Bernstein, Mark, Das, Sunit, Bader, Gary, Arrowsmith, Cheryl H., Angers, Stephane, Huang, Xi, Lupien, Mathieu, Dirks, Peter B.

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Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation von Rothbart, Scott B, Krajewski, Krzysztof, Nady, Nataliya, Tempel, Wolfram, Xue, Sheng, Badeaux, Aimee I, Barsyte-Lovejoy, Dalia, Martinez, Jorge Y, Bedford, Mark T, Fuchs, Stephen M, Arrowsmith, Cheryl H, Strahl, Brian D

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The promise and peril of chemical probes von Arrowsmith, Cheryl H, Audia, James E, Austin, Christopher, Baell, Jonathan, Bennett, Jonathan, Blagg, Julian, Bountra, Chas, Brennan, Paul E, Brown, Peter J, Bunnage, Mark E, Buser-Doepner, Carolyn, Campbell, Robert M, Carter, Adrian J, Cohen, Philip, Copeland, Robert A, Cravatt, Ben, Dahlin, Jayme L, Dhanak, Dashyant, Edwards, Aled M, Frederiksen, Mathias, Frye, Stephen V, Gray, Nathanael, Grimshaw, Charles E, Hepworth, David, Howe, Trevor, Huber, Kilian V M, Jin, Jian, Knapp, Stefan, Kotz, Joanne D, Kruger, Ryan G, Lowe, Derek, Mader, Mary M, Marsden, Brian, Mueller-Fahrnow, Anke, Müller, Susanne, O'Hagan, Ronan C, Overington, John P, Owen, Dafydd R, Rosenberg, Saul H, Ross, Ruth, Roth, Bryan, Schapira, Matthieu, Schreiber, Stuart L, Shoichet, Brian, Sundström, Michael, Superti-Furga, Giulio, Taunton, Jack, Toledo-Sherman, Leticia, Walpole, Chris, Walters, Michael A, Willson, Timothy M, Workman, Paul, Young, Robert N, Zuercher, William J

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MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin von Gallo, Marco, Coutinho, Fiona J., Vanner, Robert J., Gayden, Tenzin, Mack, Stephen C., Murison, Alex, Remke, Marc, Li, Ren, Takayama, Naoya, Desai, Kinjal, Lee, Lilian, Lan, Xiaoyang, Park, Nicole I., Barsyte-Lovejoy, Dalia, Smil, David, Sturm, Dominik, Kushida, Michelle M., Head, Renee, Cusimano, Michael D., Bernstein, Mark, Clarke, Ian D., Dick, John E., Pfister, Stefan M., Rich, Jeremy N., Arrowsmith, Cheryl H., Taylor, Michael D., Jabado, Nada, Bazett-Jones, David P., Lupien, Mathieu, Dirks, Peter B.

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PRMT5 regulates ATF4 transcript splicing and oxidative stress response von Szewczyk, Magdalena M., Luciani, Genna M., Vu, Victoria, Murison, Alex, Dilworth, David, Barghout, Samir H., Lupien, Mathieu, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia

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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells von Park, Nicole I., Guilhamon, Paul, Desai, Kinjal, McAdam, Rochelle F., Langille, Ellen, O’Connor, Madlen, Lan, Xiaoyang, Whetstone, Heather, Coutinho, Fiona J., Vanner, Robert J., Ling, Erick, Prinos, Panagiotis, Lee, Lilian, Selvadurai, Hayden, Atwal, Gurnit, Kushida, Michelle, Clarke, Ian D., Voisin, Veronique, Cusimano, Michael D., Bernstein, Mark, Das, Sunit, Bader, Gary, Arrowsmith, Cheryl H., Angers, Stephane, Huang, Xi, Lupien, Mathieu, Dirks, Peter B.

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The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population von Medina, Tiago S, Murison, Alex, Smith, Michelle, Kinker, Gabriela S, Chakravarthy, Ankur, Vitiello, Glauco A F, Turpin, Williams, Shen, Shu Yi, Yau, Helen L, Sarmento, Olga F, Faubion, William, Lupien, Mathieu, Silverberg, Mark S, Arrowsmith, Cheryl H, De Carvalho, Daniel D

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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy von Lan, Xiaoyang, Jörg, David J., Cavalli, Florence M. G., Richards, Laura M., Nguyen, Long V., Vanner, Robert J., Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M., Pellacani, Davide, Park, Nicole I., Coutinho, Fiona J., Whetstone, Heather, Selvadurai, Hayden J., Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D., Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J., Taylor, Michael D., Hirst, Martin, Eaves, Connie J., Simons, Benjamin D., Dirks, Peter B.

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Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation von Fong, Jia Yi, Pignata, Luca, Goy, Pierre-Alexis, Kawabata, Kimihito Cojin, Lee, Stanley Chun-Wei, Koh, Cheryl M., Musiani, Daniele, Massignani, Enrico, Kotini, Andriana G., Penson, Alex, Wun, Cheng Mun, Shen, Yudao, Schwarz, Megan, Low, Diana HP, Rialdi, Alexander, Ki, Michelle, Wollmann, Heike, Mzoughi, Slim, Gay, Florence, Thompson, Christine, Hart, Timothy, Barbash, Olena, Luciani, Genna M., Szewczyk, Magdalena M., Wouters, Bas J., Delwel, Ruud, Papapetrou, Eirini P., Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Minden, Mark D., Jin, Jian, Melnick, Ari, Bonaldi, Tiziana, Abdel-Wahab, Omar, Guccione, Ernesto

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Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations von Alqazzaz, Mona A., Luciani, Genna M., Vu, Victoria, Machado, Raquel A.C., Szewczyk, Magdalena M., Adamson, Ella C., Cheon, Sehyun, Li, Fengling, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia

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Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conj... von Leach, Amanda Jane, Wilson, Nicole, Arrowsmith, Beth, Beissbarth, Jemima, Mulholland, Kim, Santosham, Mathuram, Torzillo, Paul John, McIntyre, Peter, Smith-Vaughan, Heidi, Skull, Sue A, Oguoma, Victor M, Chatfield, Mark D, Lehmann, Deborah, Brennan-Jones, Christopher G, Binks, Michael J, Licciardi, Paul V, Andrews, Ross M, Snelling, Tom, Krause, Vicki, Carapetis, Jonathan, Chang, Anne B, Morris, Peter Stanley

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Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach von Merten, Eric M, Sears, John D, Leisner, Tina M, Hardy, P Brian, Ghoshal, Anirban, Hossain, Mohammad Anwar, Asressu, Kesatebrhan Haile, Brown, Peter J, Tse, Edwin G, Stashko, Michael A, Li, Kelin, Norris-Drouin, Jacqueline L, Herring, Laura E, Mordant, Angie L, Webb, Thomas S, Mills, Christine A, Barker, Natalie K, Streblow, Zachary J, Perveen, Sumera, Arrowsmith, Cheryl H, Couñago, Rafael Miguez, Arnold, Jamie J, Cameron, Craig E, Streblow, Daniel N, Moorman, Nathaniel J, Heise, Mark T, Willson, Timothy M, Popov, Konstantin I, Pearce, Kenneth H

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Abiraterone and Increased Survival in Metastatic Prostate Cancer von de Bono, Johann S, Logothetis, Christopher J, Molina, Arturo, Fizazi, Karim, North, Scott, Chu, Luis, Chi, Kim N, Jones, Robert J, Goodman, Oscar B, Saad, Fred, Staffurth, John N, Mainwaring, Paul, Harland, Stephen, Flaig, Thomas W, Hutson, Thomas E, Cheng, Tina, Patterson, Helen, Hainsworth, John D, Ryan, Charles J, Sternberg, Cora N, Ellard, Susan L, Fléchon, Aude, Saleh, Mansoor, Scholz, Mark, Efstathiou, Eleni, Zivi, Andrea, Bianchini, Diletta, Loriot, Yohann, Chieffo, Nicole, Kheoh, Thian, Haqq, Christopher M, Scher, Howard I

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Genome of the African Trypanosome Trypanosoma brucei von Berriman, Matthew, Ghedin, Elodie, Hertz-Fowler, Christiane, Blandin, Gae̊lle, Renauld, Hubert, Bartholomeu, Daniella C, Lennard, Nicola J, Caler, Elisabet, Hamlin, Nancy E, Haas, Brian, Böhme, Ulrike, Hannick, Linda, Aslett, Martin A, Shallom, Joshua, Marcello, Lucio, Hou, Lihua, Wickstead, Bill, Alsmark, U. Cecilia M, Arrowsmith, Claire, Atkin, Rebecca J, Barron, Andrew J, Bringaud, Frederic, Brooks, Karen, Carrington, Mark, Cherevach, Inna, Chillingworth, Tracey-Jane, Churcher, Carol, Clark, Louise N, Corton, Craig H, Cronin, Ann, Davies, Rob M, Djikeng, Appolinaire, Feldblyum, Tamara, Field, Mark C, Fraser, Audrey, Goodhead, Ian, Hance, Zahra, Harper, David, Harris, Barbara R, Hauser, Heidi, Hostetler, Jessica, Ivens, Al, Jagels, Kay, Johnson, David, Johnson, Justin, Jones, Kristine, Kerhornou, Arnaud X, Koo, Hean, Larke, Natasha, Landfear, Scott, Larkin, Christopher, Leech, Vanessa, Line, Alexandra, Lord, Angela, MacLeod, Annette, Mooney, Paul J, Moule, Sharon, Martin, David M. A, Morgan, Gareth W, Mungall, Karen, Ormond, Doug, Pai, Grace, Peacock, Chris S, Peterson, Jeremy, Quail, Michael A, Rabbinowitsch, Ester, Rajandream, Marie-Adele, Reitter, Chris, Salzberg, Steven L, Sanders, Mandy, Schobel, Seth, Sharp, Sarah, Simmonds, Mark, Simpson, Anjana J, Tallon, Luke, Turner, C. Michael R, Tait, Andrew, Tivey, Adrian R, Van Aken, Susan, Walker, Danielle, Wanless, David, Wang, Shiliang, White, Brian, White, Owen, Whitehead, Sally, Woodward, John, Wortman, Jennifer, Adams, Mark D, Embley, T. Martin, Gull, Keith, Ullu, Elisabetta, Barry, J. David, Fairlamb, Alan H, Opperdoes, Fred, Barrell, Barclay G, Donelson, John E, Hall, Neil, Fraser, Claire M, Melville, Sara E, El-Sayed, Najib M

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Breakdown of simple female genital fistula repair after 7 day versus 14 day postoperative bladder catheterisation: a randomised, controlled, open-label, non-inferiority trial von Barone, Mark A, Dr, Widmer, Mariana, MSc, Arrowsmith, Steven, MD, Ruminjo, Joseph, MMed, Seuc, Armando, PhD, Landry, Evelyn, MPH, Barry, Thierno Hamidou, MD, Danladi, Dantani, MBBS, Djangnikpo, Lucien, MD, Gbawuru-Mansaray, Tagie, MBChB, Harou, Issoufa, MD, Lewis, Alyona, MD, Muleta, Mulu, MD, Nembunzu, Dolorès, MD, Olupot, Robert, MMed, Sunday-Adeoye, Ileogben, Prof, Wakasiaka, Weston Khisa, MMed, Landoulsi, Sihem, MSc, Delamou, Alexandre, MD, Were, Lilian, MPH, Frajzyngier, Vera, PhD, Beattie, Karen, MA, Gülmezoglu, A Metin, MD

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Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6 von Harding, Rachel J., Franzoni, Ivan, Mann, Mandeep K., Szewczyk, Magdalena M., Mirabi, Bijan, Ferreira de Freitas, Renato, Owens, Dominic D. G., Ackloo, Suzanne, Scheremetjew, Alexej, Juarez-Ornelas, Kevin A., Sanichar, Randy, Baker, Rachel J., Dank, Christian, Brown, Peter J., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Schapira, Matthieu, Lautens, Mark, Arrowsmith, Cheryl H.

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Otitis media outcomes of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine and 13-valent pneumococcal conjugate vaccine schedule at 1-2-4-6 month... von Leach, Amanda Jane, Mulholland, Edward Kim, Santosham, Mathuram, Torzillo, Paul John, McIntyre, Peter, Smith-Vaughan, Heidi, Wilson, Nicole, Arrowsmith, Beth, Beissbarth, Jemima, Chatfield, Mark D, Oguoma, Victor M, Morris, Peter Stanley

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PRMT5 inhibition disrupts splicing and stemness in glioblastoma von Sachamitr, Patty, Ho, Jolene C., Ciamponi, Felipe E., Ba-Alawi, Wail, Coutinho, Fiona J., Guilhamon, Paul, Kushida, Michelle M., Cavalli, Florence M. G., Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M., Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M., Restall, Ian, Caudy, Amy, Röst, Hannes L., Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D., Spears, Julian, Bader, Gary D., Pugh, Trevor J., Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H., Weiss, Samuel, Massirer, Katlin B., Prinos, Panagiotis, Arrowsmith, Cheryl H., Dirks, Peter B.

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Outcomes in obstetric fistula care: a literature review von Arrowsmith, Steven D, Barone, Mark A, Ruminjo, Joseph

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