Differential Effects of Munc18s on Multiple Degranulation-Relevant Trans-SNARE Complexes von Xu, Hao, Arnold, Matthew Grant, Kumar, Sushmitha Vijay

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Munc18a clusters SNARE-bearing liposomes prior to trans -SNARE zippering von Arnold, Matthew Grant, Adhikari, Pratikshya, Kang, Baobin, Xu 徐昊, Hao

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Comparison of multi-parallel qPCR and double-slide Kato-Katz for detection of soil-transmitted helminth infection among children in rural Bangladesh von Benjamin-Chung, Jade, Pilotte, Nils, Ercumen, Ayse, Grant, Jessica R, Maasch, Jacqueline R M A, Gonzalez, Andrew M, Ester, Ashanta C, Arnold, Benjamin F, Rahman, Mahbubur, Haque, Rashidul, Hubbard, Alan E, Luby, Stephen P, Williams, Steven A, Colford, Jr, John M

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Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection von Arnold, Samuel L. M., Choi, Ryan, Hulverson, Matthew A., Schaefer, Deborah A., Vinayak, Sumiti, Vidadala, Rama S. R., McCloskey, Molly C., Whitman, Grant R., Huang, Wenlin, Barrett, Lynn K., Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Riggs, Michael W., Striepen, Boris, Van Voorhis, Wesley C.

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Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults von Jain, Seema, Self, Wesley H, Wunderink, Richard G, Fakhran, Sherene, Balk, Robert, Bramley, Anna M, Reed, Carrie, Grijalva, Carlos G, Anderson, Evan J, Courtney, D. Mark, Chappell, James D, Qi, Chao, Hart, Eric M, Carroll, Frank, Trabue, Christopher, Donnelly, Helen K, Williams, Derek J, Zhu, Yuwei, Arnold, Sandra R, Ampofo, Krow, Waterer, Grant W, Levine, Min, Lindstrom, Stephen, Winchell, Jonas M, Katz, Jacqueline M, Erdman, Dean, Schneider, Eileen, Hicks, Lauri A, McCullers, Jonathan A, Pavia, Andrew T, Edwards, Kathryn M, Finelli, Lyn

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Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis von Lee, Sangun, Ginese, Melanie, Beamer, Gillian, Danz, Hillary R, Girouard, Donald J, Chapman-Bonofiglio, Susan P, Lee, Minhee, Hulverson, Matthew A, Choi, Ryan, Whitman, Grant R, Ojo, Kayode K, Arnold, Samuel L M, Van Voorhis, Wesley C, Tzipori, Saul

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Development of 5‑Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy von Huang, Wenlin, Hulverson, Matthew A, Choi, Ryan, Arnold, Samuel L. M, Zhang, Zhongsheng, McCloskey, Molly C, Whitman, Grant R, Hackman, Robert C, Rivas, Kasey L, Barrett, Lynn K, Ojo, Kayode K, Van Voorhis, Wesley C, Fan, Erkang

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In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzo... von Imhof, Dennis, Anghel, Nicoleta, Winzer, Pablo, Balmer, Vreni, Ramseier, Jessica, Hänggeli, Kai, Choi, Ryan, Hulverson, Matthew A., Whitman, Grant R., Arnold, Samuel L.M., Ojo, Kayode K., Van Voorhis, Wesley C., Doggett, J. Stone, Ortega-Mora, Luis M., Hemphill, Andrew

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Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned von Choi, Ryan, Hulverson, Matthew A., Huang, Wenlin, Vidadala, Rama S.R., Whitman, Grant R., Barrett, Lynn K., Schaefer, Deborah A., Betzer, Dana P., Riggs, Michael W., Doggett, J. Stone, Hemphill, Andrew, Ortega-Mora, Luis Miguel, McCloskey, Molly C., Arnold, Samuel L.M., Hackman, Robert C., Marsh, Kennan C., Lynch, James J., Freiberg, Gail M., Leroy, Bruce E., Kempf, Dale J., Choy, Robert K.M., de Hostos, Eugenio L., Maly, Dustin J., Fan, Erkang, Ojo, Kayode K., Van Voorhis, Wesley C.

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Zwitterionic Stabilization of a Reactive Cobalt Tris-Isocyanide Monoanion by Cation Coordination von Carpenter, Alex E., Margulieux, Grant W., Millard, Matthew D., Moore, Curtis E., Weidemann, Nils, Rheingold, Arnold L., Figueroa, Joshua S.

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Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy von Hulverson, Matthew A., Vinayak, Sumiti, Choi, Ryan, Schaefer, Deborah A., Castellanos-Gonzalez, Alejandro, Vidadala, Rama S. R., Brooks, Carrie F., Herbert, Gillian T., Betzer, Dana P., Whitman, Grant R., Sparks, Hayley N., Arnold, Samuel L. M., Rivas, Kasey L., Barrett, Lynn K., White, A. Clinton, Maly, Dustin J., Riggs, Michael W., Striepen, Boris, Van Voorhis, Wesley C., Ojo, Kayode K.

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Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis von Hulverson, Matthew A, Choi, Ryan, Schaefer, Deborah A, Betzer, Dana P, McCloskey, Molly C, Whitman, Grant R, Huang, Wenlin, Lee, Sangun, Pranata, Andy, McLeod, Malcolm D, Marsh, Kennan C, Kempf, Dale J, LeRoy, Bruce E, Zafiratos, Mark T, Bielinski, Aimee L, Hackman, Robert C, Ojo, Kayode K, Arnold, Samuel L M, Barrett, Lynn K, Tzipori, Saul, Riggs, Michael W, Fan, Erkang, Van Voorhis, Wesley C

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Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo von Anghel, Nicoleta, Imhof, Dennis, Winzer, Pablo, Balmer, Vreni, Ramseier, Jessica, Haenggeli, Kai, Choi, Ryan, Hulverson, Matthew A., Whitman, Grant R., Arnold, Samuel L.M., Ojo, Kayode K., Van Voorhis, Wesley C., Doggett, J. Stone, Ortega-Mora, Luis M., Hemphill, Andrew

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Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis von Hulverson, Matthew A., Choi, Ryan, Arnold, Samuel L.M., Schaefer, Deborah A., Hemphill, Andrew, McCloskey, Molly C., Betzer, Dana P., Müller, Joachim, Vidadala, Rama S.R., Whitman, Grant R., Rivas, Kasey L., Barrett, Lynn K., Hackman, Robert C., Love, Melissa S., McNamara, Case W., Shaughnessy, Thomas K., Kondratiuk, Alison, Kurnick, Matthew, Banfor, Patricia N., Lynch, James J., Freiberg, Gail M., Kempf, Dale J., Maly, Dustin J., Riggs, Michael W., Ojo, Kayode K., Van Voorhis, Wesley C.

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P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium von Arnold, Samuel L M, Choi, Ryan, Hulverson, Matthew A, Whitman, Grant R, Mccloskey, Molly C, Dorr, Carlie S, Vidadala, Rama S R, Khatod, Mansi, Morada, Mary, Barrett, Lynn K, Maly, Dustin J, Yarlett, Nigel, Van Voorhis, Wesley C

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One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases von Van Voorhis, Wesley C., Hulverson, Matthew A., Choi, Ryan, Huang, Wenlin, Arnold, Samuel L.M., Schaefer, Deborah A., Betzer, Dana P., Vidadala, Rama S.R., Lee, Sangun, Whitman, Grant R., Barrett, Lynn K., Maly, Dustin J., Riggs, Michael W., Fan, Erkang, Kennedy, Thomas J., Tzipori, Saul, Doggett, J. Stone, Winzer, Pablo, Anghel, Nicoleta, Imhof, Dennis, Müller, Joachim, Hemphill, Andrew, Ferre, Ignacio, Sanchez-Sanchez, Roberto, Ortega-Mora, Luis Miguel, Ojo, Kayode K.

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Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis von Hulverson, Matthew A, Bruzual, Igor, McConnell, Erin V, Huang, Wenlin, Vidadala, Rama S R, Choi, Ryan, Arnold, Samuel L M, Whitman, Grant R, McCloskey, Molly C, Barrett, Lynn K, Rivas, Kasey L, Scheele, Suzanne, DeRocher, Amy E, Parsons, Marilyn, Ojo, Kayode K, Maly, Dustin J, Fan, Erkang, Van Voorhis, Wesley C, Doggett, J Stone

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Atmospheric oxygen as a tracer for fossil fuel carbon dioxide: a sensitivity study in the UK von Chawner, Hannah, Saboya, Eric, Adcock, Karina E, Arnold, Tim, Artioli, Yuri, Dylag, Caroline, Forster, Grant L, Ganesan, Anita, Graven, Heather, Lessin, Gennadi, Levy, Peter, Luijkx, Ingrid T, Manning, Alistair, Pickers, Penelope A, Rennick, Chris, Rödenbeck, Christian, Rigby, Matthew

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Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers von Shlien, Adam, Campbell, Brittany B, de Borja, Richard, Alexandrov, Ludmil B, Merico, Daniele, Wedge, David, Van Loo, Peter, Tarpey, Patrick S, Coupland, Paul, Behjati, Sam, Pollett, Aaron, Lipman, Tatiana, Heidari, Abolfazl, Deshmukh, Shriya, Avitzur, Na'ama, Meier, Bettina, Gerstung, Moritz, Hong, Ye, Merino, Diana M, Ramakrishna, Manasa, Remke, Marc, Arnold, Roland, Panigrahi, Gagan B, Thakkar, Neha P, Hodel, Karl P, Henninger, Erin E, Göksenin, A Yasemin, Bakry, Doua, Charames, George S, Druker, Harriet, Lerner-Ellis, Jordan, Mistry, Matthew, Dvir, Rina, Grant, Ronald, Elhasid, Ronit, Farah, Roula, Taylor, Glenn P, Nathan, Paul C, Alexander, Sarah, Ben-Shachar, Shay, Ling, Simon C, Gallinger, Steven, Constantini, Shlomi, Dirks, Peter, Huang, Annie, Scherer, Stephen W, Grundy, Richard G, Durno, Carol, Aronson, Melyssa, Gartner, Anton, Meyn, M Stephen, Taylor, Michael D, Pursell, Zachary F, Pearson, Christopher E, Malkin, David, Futreal, P Andrew, Stratton, Michael R, Bouffet, Eric, Hawkins, Cynthia, Campbell, Peter J, Tabori, Uri

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Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study von Dowty, James G., Lee, Grant, Templeton, Allyson S., Alvarez, Karin, Ankathil, Ravindran, Austin, Rachel, Barca-Tierno, Verónica, Berthet, Pascaline, Boisjoli, Talya, Briollais, Laurent, Brunet, Joan, Bucksch, Karolin, Buettner, Reinhard, Burn, John, Caldés, Trinidad, Casey, Graham, Chew, Min H., Choi, Yun-hee, Church, James, Clendenning, Mark, Colas, Chrystelle, Coupier, Isabelle, de la Chapelle, Albert, Dębniak, Tadeusz, Della Valle, Adriana, Dominguez-Valentin, Mev, Engel, Christoph, Esperon, Patricia, Foulkes, William, Frebourg, Thierry, Gallinger, Steven, Garre, Pilar, Genuardi, Maurizio, Giraud, Sophie, Goodwin, Annabel, Green, Kate, Guindalini, Rodrigo S.C., Half, Elizabeth E., Hampel, Heather, Ho, Judy W.C., Hoogerbrugge, Nicoline, Hüneburg, Robert, Huntley, Vanessa, Jensen, Uffe B, Juhari, Wan K.W., Kloor, Matthias, Kupfer, Sonia S., Lagerstedt-Robinson, Kristina, Lalloo, Fiona, Lautrup, Charlotte K., Leggett, Barbara A., Lejeune, Sophie, Lindor, Noralane, Loeffler, Markus, Lucassen, Anneke M, Lynch, Patrick M., Møller, Pål, Navarro, Matilde, Neffa, Florencia, Neklason, Deborah, Nixon, Dawn M., Palmero, Edenir I., Pande, Mala, Parry, Susan, Pineda, Marta, Qiu, Jay, Ramesar, Raj, Rasmussen, Lene J., Redler, Silke, Ricciardiello, Luigi, Schulmann, Karsten, Schuster, Helène, Senter, Leigha, Seppälä, Toni T, Shtoyerman, Rakefet, Sijmons, Rolf H., Soto, Jose Luis, Spigelman, Allan, Steinke-Lange, Verena, Stoffel, Elena M., Strassburg, Christian P., Sunde, Lone, Therkildsen, Christina, Thibodeau, Steve, Tucker, Katherine M., Tunca, Berrin, Uhrhammer, Nancy, Vaccaro, Carlos, van Duijnhoven, Fränzel J.B., van Wanzeele, Meghan J., Vasen, Hans F.A., von Knebel Doeberitz, Magnus, von Salomé, Jenny, Ward, Robyn L., Wise, Paul E., Yamaguchi, Tatsuro, Zahary, Mohd N., Hopper, John L., Haile, Robert W., Jenkins, Mark A.

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