Identification and Characterization of the First Small Molecule Inhibitor of MDMX von Reed, Damon, Shen, Ying, Shelat, Anang A., Arnold, Leggy A., Ferreira, Antonio M., Zhu, Fangyi, Mills, Nicholas, Smithson, David C., Regni, Catherine A., Bashford, Donald, Cicero, Samantha A., Schulman, Brenda A., Jochemsen, Aart G., Guy, R. Kiplin, Dyer, Michael A.

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surface on the androgen receptor that allosterically regulates coactivator binding von Estébanez-Perpiñá, Eva, Arnold, Alexander A, Nguyen, Phuong, Rodrigues, Edson Delgado, Mar, Ellena, Bateman, Raynard, Pallai, Peter, Shokat, Kevan M, Baxter, John D, Guy, R. Kiplin, Webb, Paul, Fletterick, Robert J

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Novel VDR antagonists based on the GW0742 scaffold von Teske, Kelly A., Bogart, Jonathan W., Arnold, Leggy A.

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Dysregulation of tetrahydrobiopterin metabolism in myalgic encephalomyelitis/chronic fatigue syndrome by pentose phosphate pathway von Bulbule, Sarojini, Gottschalk, Carl Gunnar, Drosen, Molly E, Peterson, Daniel, Arnold, Leggy A, Roy, Avik

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Exploring structural features of sleep-enhancing peptides derived from casein hydrolysates by chemometrics and random forest methodology von Qian, Jingjing, Yu, Fengjie, Arnold, Leggy A., Saha, Arjun, Zheng, Lin, Zhao, Mouming

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A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABAA Receptor von Li, Guanguan, Nieman, Amanda N., Mian, Md Yeunus, Zahn, Nicolas M., Mikulsky, Brandon N., Poe, Michael M., Methuku, Kashi R., Liu, Yongfeng, Cook, James M., Stafford, Douglas C., Arnold, Leggy A.

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JRM-28, a Novel HDAC2 Inhibitor, Upregulates Plasticity-Associated Proteins in Hippocampal Neurons and Enhances Morphological Plasticity via Activation of CREB: Implications for Al... von Rahman, A F M Towheedur, Bulbule, Sarojini, Belayet, Jawad Bin, Benko, Anna, Gottschalk, Carl Gunnar, Frick, David N, Arnold, Leggy A, Hossain, M Mahmun, Roy, Avik

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Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays von Mukherjee, Sourav, Hanson, Alicia M, Shadrick, William R, Ndjomou, Jean, Sweeney, Noreena L, Hernandez, John J, Bartczak, Diana, Li, Kelin, Frankowski, Kevin J, Heck, Julie A, Arnold, Leggy A, Schoenen, Frank J, Frick, David N

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A fluorescence-based high throughput assay for the determination of small molecule−human serum albumin protein binding von McCallum, Megan M., Pawlak, Alan J., Shadrick, William R., Simeonov, Anton, Jadhav, Ajit, Yasgar, Adam, Maloney, David J., Arnold, Leggy A.

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Inhibition of a viral enzyme by a small-molecule dimer disruptor von Roels, Christina M, Guy, R Kiplin, Shahian, Tina, Lazic, Ana, Craik, Charles S, Velusamy, Priya, Arnold, Leggy A, Lee, Gregory M

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Design and Evaluation of Heterobivalent PAR1–PAR2 Ligands as Antagonists of Calcium Mobilization von Majewski, Mark W, Gandhi, Disha M, Rosas, Ricardo, Kodali, Revathi, Arnold, Leggy A, Dockendorff, Chris

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Discovery of the First Irreversible Small Molecule Inhibitors of the Interaction between the Vitamin D Receptor and Coactivators von Nandhikonda, Premchendar, Lynt, Wen Z, McCallum, Megan M, Ara, Tahniyath, Baranowski, Athena M, Yuan, Nina Y, Pearson, Dana, Bikle, Daniel D, Guy, R. Kiplin, Arnold, Leggy A

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Discovery and Optimization of Novel Hydrogen Peroxide Activated Aromatic Nitrogen Mustard Derivatives as Highly Potent Anticancer Agents von Chen, Wenbing, Fan, Heli, Balakrishnan, Kumudha, Wang, Yibin, Sun, Huabing, Fan, Yukai, Gandhi, Varsha, Arnold, Leggy A, Peng, Xiaohua

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Quantification of the Vitamin D Receptor−Coregulator Interaction von Teichert, Arnaud, Arnold, Leggy A, Otieno, Steve, Oda, Yuko, Augustinaite, Indre, Geistlinger, Tim R, Kriwacki, Richard W, Guy, R. Kiplin, Bikle, Daniel D

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Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice von McMurray, Katherine M. J., Sidhu, Preetpal S., Cook, James M., Arnold, Leggy A., Palmer, Abraham A.

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Enantioselective Catalytic Conjugate Addition of Dialkylzinc Reagents using Copper–Phosphoramidite Complexes; Ligand Variation and Non-linear Effects von Arnold, Leggy A, Imbos, Rosalinde, Mandoli, Alessandro, de Vries, André H.M, Naasz, Robert, Feringa, Ben L

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Anticancer activity of VDR-coregulator inhibitor PS121912 von Sidhu, Preetpal S., Teske, Kelly, Feleke, Belaynesh, Yuan, Nina Y., Guthrie, Margaret L., Fernstrum, Grant B., Vyas, Nishita D., Han, Lanlan, Preston, Joshua, Bogart, Jonathan W., Silvaggi, Nicholas R., Cook, James M., Singh, Rakesh K., Bikle, Daniel D., Arnold, Leggy A.

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Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model von Moore, Richard G, Lange, Thilo S, Robinson, Katina, Kim, Kyu K, Uzun, Alper, Horan, Timothy C, Kawar, Nada, Yano, Naohiro, Chu, Sharon R, Mao, Quanfu, Brard, Laurent, DePaepe, Monique E, Padbury, James F, Arnold, Leggy A, Brodsky, Alexander, Shen, Tun-Li, Singh, Rakesh K

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Synthesis of chiral GABAA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression von Li, Guanguan, Stephen, Michael R., Kodali, Revathi, Zahn, Nicolas M., Poe, Michael M., Tiruveedhula, V. V. N. Phani Babu, Huber, Alec T., Schussman, Melissa K., Qualmann, Krista, Panhans, Cristina M., Raddatz, Nicholas J., Baker, David A., Prevot, Thomas D., Banasr, Mounira, Sibille, Etienne, Arnold, Leggy A., Cook, James M.

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Calcitroic Acid–A Review von Yu, Olivia B, Arnold, Leggy A

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