Telomere Length Homeostasis Is Achieved via a Switch between Telomerase- Extendible and -Nonextendible States von Teixeira, M.Teresa, Arneric, Milica, Sperisen, Peter, Lingner, Joachim

Volltext

Impact of Behavior on Central and Peripheral Circadian Clocks in the Common Vole Microtus arvalis, a Mammal with Ultradian Rhythms von van der Veen, Daan R., Le Minh, Nguyet, Gos, Pascal, Arneric, Milica, Gerkema, Menno P., Schibler, Ueli

Volltext

Rad52 SUMOylation affects the efficiency of the DNA repair von Altmannova, V., Eckert-Boulet, N., Arneric, M., Kolesar, P., Chaloupkova, R., Damborsky, J., Sung, P., Zhao, X., Lisby, M., Krejci, L., Colavito, S., Macris-Kiss, M., Seong, C., Gleeson, O., Greene, E. C., Klein, H. L.

Volltext

The yeast protein Xtc1 functions as a direct transcriptional repressor von Traven, Ana, Starešinčić, Lidija, Arnerić, Milica, Sopta, Mary

Volltext

The Retinoblastoma Family of Proteins Directly Represses Transcription in Saccharomyces cerevisiae von Arnerić, Milica, Traven, Ana, Starešinčić, Lidija, Sopta, Mary

Volltext

Role of voltage-gated calcium channels in ascending pain pathways von Zamponi, Gerald W, Lewis, Richard J, Todorovic, Slobodan M, Arneric, Stephen P, Snutch, Terrance P

Volltext

Analgesic Effects of a Substituted N-Triazole Oxindole (TROX-1), a State-Dependent, Voltage-Gated Calcium Channel 2 Blocker von Abbadie, Catherine, McManus, Owen B., Sun, Shu-Yu, Bugianesi, Randal M., Dai, Ge, Haedo, Rodolfo J., Herrington, James B., Kaczorowski, Gregory J., Smith, McHardy M., Swensen, Andrew M., Warren, Vivien A., Williams, Brande, Arneric, Stephen P., Eduljee, Cyrus, Snutch, Terrance P., Tringham, Elizabeth W., Jochnowitz, Nina, Liang, Annie, Euan MacIntyre, D., McGowan, Erin, Mistry, Shruti, White, Valerie V., Hoyt, Scott B., London, Clare, Lyons, Kathryn A., Bunting, Patricia B., Volksdorf, Sylvia, Duffy, Joseph L.

Volltext

Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors von Bannon, A. W., Decker, M. W., Holladay, M. W., Curzon, P., Donnelly-Roberts, D., Puttfarcken, P. S., Bitner, R. S., Diaz, A., Dickenson, A. H., Porsolt, R. D., Williams, M., Arneric, S. P.

Volltext

Emerging Molecular Approaches to Pain Therapy von Williams, Michael, Kowaluk, Elizabeth A, Arneric, Stephen P

Volltext

Biometric monitoring devices for assessing end points in clinical trials: developing an ecosystem von Arnerić, Stephen P., Cedarbaum, Jesse M., Khozin, Sean, Papapetropoulos, Spyros, Hill, Derek L., Ropacki, Michael, Rhodes, Jane, Dacks, Penny A., Hudson, Lynn D., Gordon, Mark Forrest, Kern, Volker D., Romero, Klaus, Vradenburg, George, Au, Rhoda, Karlin, Daniel R., Facheris, Maurizio F., Fitzer-Attas, Cheryl J., Vitolo, Ottavio V., Wang, Jian, Miller, Bradley M., Kaye, Jeffrey A.

Volltext

Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels von Swensen, Andrew M, Herrington, James, Bugianesi, Randal M, Dai, Ge, Haedo, Rodolfo J, Ratliff, Kevin S, Smith, McHardy M, Warren, Vivien A, Arneric, Stephen P, Eduljee, Cyrus, Parker, David, Snutch, Terrance P, Hoyt, Scott B, London, Clare, Duffy, Joseph L, Kaczorowski, Gregory J, McManus, Owen B

Volltext

A Novel Positive Allosteric Modulator of the alpha 7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization von Hurst, Raymond S, Hajos, Mihaly, Raggenbass, Mario, Wall, Theron M, Higdon, Nicole R, Lawson, Judy A, Rutherford-Root, Karen L, Berkenpas, Mitchell B, Hoffmann, W E, Piotrowski, David W, Groppi, Vincent E, Allaman, Geraldine, Ogier, Roch, Bertrand, Sonia, Bertrand, Daniel, Arneric, Stephen P

Volltext

Tailoring chronic pain treatments for the elderly: are we prepared for the challenge? von Arneric, Stephen P., Laird, Jennifer M.A., Chappell, Amy S., Kennedy, Jeffrey D.

Volltext

Presenilin-1 and -2 Are Molecular Targets for γ-Secretase Inhibitors von Seiffert, Dietmar, Bradley, Jodi D., Rominger, Cynthia M., Rominger, David H., Yang, Fude, Meredith, Jere E., Wang, Qian, Roach, Arthur H., Thompson, Lorin A., Spitz, Susan M., Higaki, Jeffrey N., Prakash, Shimoga R., Combs, Andrew P., Copeland, Robert A., Arneric, Stephen P., Hartig, Paul R., Robertson, David W., Cordell, Barbara, Stern, Andrew M., Olson, Richard E., Zaczek, Robert

Volltext

Discovery of N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive... von Wishka, Donn G, Walker, Daniel P, Yates, Karen M, Reitz, Steven C, Jia, Shaojuan, Myers, Jason K, Olson, Kirk L, Jacobsen, E. Jon, Wolfe, Mark L, Groppi, Vincent E, Hanchar, Alexander J, Thornburgh, Bruce A, Cortes-Burgos, Luz A, Wong, Erik H. F, Staton, Brian A, Raub, Thomas J, Higdon, Nicole R, Wall, Theron M, Hurst, Raymond S, Walters, Rodney R, Hoffmann, William E, Hajos, Mihaly, Franklin, Stanley, Carey, Galen, Gold, Lisa H, Cook, Karen K, Sands, Steven B, Zhao, Sabrina X, Soglia, John R, Kalgutkar, Amit S, Arneric, Stephen P, Rogers, Bruce N

Volltext

A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization von Hurst, Raymond S., Hajós, Mihaly, Raggenbass, Mario, Wall, Theron M., Higdon, Nicole R., Lawson, Judy A., Rutherford-Root, Karen L., Berkenpas, Mitchell B., Hoffmann, W. E., Piotrowski, David W., Groppi, Vincent E., Allaman, Geraldine, Ogier, Roch, Bertrand, Sonia, Bertrand, Daniel, Arneric, Stephen P.

Volltext

New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures von Boxer, Adam L., Gold, Michael, Feldman, Howard, Boeve, Bradley F., Dickinson, Susan L.-J., Fillit, Howard, Ho, Carole, Paul, Robert, Pearlman, Rodney, Sutherland, Margaret, Verma, Ajay, Arneric, Stephen P., Alexander, Brian M., Dickerson, Bradford C., Dorsey, Earl Ray, Grossman, Murray, Huey, Edward D., Irizarry, Michael C., Marks, William J., Masellis, Mario, McFarland, Frances, Niehoff, Debra, Onyike, Chiadi U., Paganoni, Sabrina, Panzara, Michael A., Rockwood, Kenneth, Rohrer, Jonathan D., Rosen, Howard, Schuck, Robert N., Soares, Holly D., Tatton, Nadine

Volltext

Identification and Initial Structure−Activity Relationships of (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting vi... von Holladay, Mark W, Wasicak, James T, Lin, Nan-Horng, He, Yun, Ryther, Keith B, Bannon, Anthony W, Buckley, Michael J, Kim, David J. B, Decker, Michael W, Anderson, David J, Campbell, Jeffrey E, Kuntzweiler, Theresa A, Donnelly-Roberts, Diana L, Piattoni-Kaplan, Marietta, Briggs, Clark A, Williams, Michael, Arneric, Stephen P

Volltext

Role of the Nucleus Raphe Magnus in Antinociception Produced by ABT-594: Immediate Early Gene Responses Possibly Linked to Neuronal Nicotinic Acetylcholine Receptors on Serotonergi... von Bitner, R. Scott, Nikkel, Arthur L, Curzon, Peter, Arneric, Stephen P, Bannon, Anthony W, Decker, Michael W

Volltext

Diversity of neuronal nicotinic acetylcholine receptors: Lessons from behavior and implications for cns therapeutics von Decker, Michael W., Brioni, Jorge D., Bannon, Anthony W., Arneric, Stephen P.

Volltext