Molecular Genetics of Acute Lymphoblastic Leukemia von Armstrong, Scott A, Look, A Thomas

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FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress von Tothova, Zuzana, Kollipara, Ramya, Huntly, Brian J., Lee, Benjamin H., Castrillon, Diego H., Cullen, Dana E., McDowell, Elizabeth P., Lazo-Kallanian, Suzan, Williams, Ifor R., Sears, Christopher, Armstrong, Scott A., Passegué, Emmanuelle, DePinho, Ronald A., Gilliland, D. Gary

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H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias von Krivtsov, Andrei V., Feng, Zhaohui, Lemieux, Madeleine E., Faber, Joerg, Vempati, Sridhar, Sinha, Amit U., Xia, Xiaobo, Jesneck, Jonathan, Bracken, Adrian P., Silverman, Lewis B., Kutok, Jeffery L., Kung, Andrew L., Armstrong, Scott A.

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CAAX Geranylgeranyl Transferase Transfers Farnesyl as Efficiently as Geranylgeranyl to RhoB (∗) von Armstrong, Scott A., Hannah, Voe C., Goldstein, Joseph L., Brown, Michael S.

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Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia von Mar, B G, Bullinger, L, Basu, E, Schlis, K, Silverman, L B, Döhner, K, Armstrong, S A

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Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML von Morgado-Palacin, Isabel, Day, Amanda, Murga, Matilde, Lafarga, Vanesa, Anton, Marta Elena, Tubbs, Anthony, Chen, Hua Tang, Ergan, Aysegul, Anderson, Rhonda, Bhandoola, Avinash, Pike, Kurt G, Barlaam, Bernard, Cadogan, Elaine, Wang, Xi, Pierce, Andrew J, Hubbard, Chad, Armstrong, Scott A, Nussenzweig, André, Fernandez-Capetillo, Oscar

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Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo von Arreba-Tutusaus, P, Mack, T S, Bullinger, L, Schnöder, T M, Polanetzki, A, Weinert, S, Ballaschk, A, Wang, Z, Deshpande, A J, Armstrong, S A, Döhner, K, Fischer, T, Heidel, F H

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia von Golub, Todd R, Korsmeyer, Stanley J, Armstrong, Scott A, Staunton, Jane E, Silverman, Lewis B, Pieters, Rob, den Boer, Monique L, Minden, Mark D, Sallan, Stephen E, Lander, Eric S

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Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation von Ferrando, Adolfo A., Armstrong, Scott A., Neuberg, Donna S., Sallan, Stephen E., Silverman, Lewis B., Korsmeyer, Stanley J., Look, A. Thomas

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MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment von Stubbs, M C, Kim, Y M, Krivtsov, A V, Wright, R D, Feng, Z, Agarwal, J, Kung, A L, Armstrong, S A

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FLT3 mutations in childhood acute lymphoblastic leukemia von Armstrong, Scott A., Mabon, Meghann E., Silverman, Lewis B., Li, Aihong, Gribben, John G., Fox, Edward A., Sallan, Stephen E., Korsmeyer, Stanley J.

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Inhibition of FLT3 in MLL: Validation of a therapeutic target identified by gene expression based classification von Armstrong, Scott A, Kung, Andrew L, Mabon, Meghann E, Silverman, Lewis B, Stam, Ronald W, Den Boer, Monique L, Pieters, Rob, Kersey, John H, Sallan, Stephen E, Fletcher, Jonathan A, Golub, Todd R, Griffin, James D, Korsmeyer, Stanley J

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Targeting FLT3 in primary MLL-gene–rearranged infant acute lymphoblastic leukemia von Stam, Ronald W., den Boer, Monique L., Schneider, Pauline, Nollau, Peter, Horstmann, Martin, Beverloo, H. Berna, van der Voort, Ella, Valsecchi, Maria G., de Lorenzo, Paola, Sallan, Stephen E., Armstrong, Scott A., Pieters, Rob

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Linking miRNA Regulation to BCR-ABL Expression: The Next Dimension von Faber, Jörg, Gregory, Richard I., Armstrong, Scott A.

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Genome-Wide SNP Analysis in Cancer: Leukemia Shows the Way von Wang, Yingzi, Armstrong, Scott A.

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Differential mRNA expression of Ara-C–metabolizing enzymes explains Ara-C sensitivity in MLL gene–rearranged infant acute lymphoblastic leukemia von Stam, Ronald W., den Boer, Monique L., Meijerink, Jules P.P., Ebus, Marli E.G., Peters, Godefridus J., Noordhuis, Paul, Janka-Schaub, Gritta E., Armstrong, Scott A., Korsmeyer, Stanley J., Pieters, Rob

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Defective Forebrain Development in Mice Lacking gp330/Megalin von Willnow, Thomas E., Hilpert, Jan, Armstrong, Scott A., Rohlmann, Astrid, Hammer, Robert E., Burns, Dennis K., Herz, Joachim

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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease von Wang, Jing, Iwasaki, Hiromi, Krivtsov, Andrei, Febbo, Phillip G, Thorner, Aaron R, Ernst, Patricia, Anastasiadou, Ema, Kutok, Jeffery L, Kogan, Scott C, Zinkel, Sandra S, Fisher, Jill K, Hess, Jay L, Golub, Todd R, Armstrong, Scott A, Akashi, Koichi, Korsmeyer, Stanley J

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Casein Kinase II-mediated Phosphorylation of the C Terminus of Sp1 Decreases Its DNA Binding Activity von Armstrong, S A, Barry, D A, Leggett, R W, Mueller, C R

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Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo von Willnow, T.E. (University of Texas Southeastern Medical Center, Dallas, TX.), Armstrong, S.A, Hammer, R.E, Herz, J

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