Adaptive Therapy von GATENBY, Robert A, SILVA, Ariosto S, GILLIES, Robert J, FRIEDEN, B. Roy

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Classifying the evolutionary and ecological features of neoplasms von Maley, Carlo C., Aktipis, Athena, Graham, Trevor A., Sottoriva, Andrea, Boddy, Amy M., Janiszewska, Michalina, Silva, Ariosto S., Gerlinger, Marco, Yuan, Yinyin, Pienta, Kenneth J., Anderson, Karen S., Gatenby, Robert, Swanton, Charles, Posada, David, Wu, Chung-I, Schiffman, Joshua D., Hwang, E. Shelley, Polyak, Kornelia, Anderson, Alexander R. A., Brown, Joel S., Greaves, Mel, Shibata, Darryl

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Evolutionary approaches to prolong progression-free survival in breast cancer von Silva, Ariosto S, Kam, Yoonseok, Khin, Zayar P, Minton, Susan E, Gillies, Robert J, Gatenby, Robert A

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The Potential Role of Systemic Buffers in Reducing Intratumoral Extracellular pH and Acid-Mediated Invasion von SILVA, Ariosto S, YUNES, Jose A, GILLIES, Robert J, GATENBY, Robert A

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BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models von Zhao, Xiaohong, Ren, Yuan, Lawlor, Matthew, Shah, Bijal D., Park, Paul M.C., Lwin, Tint, Wang, Xuefeng, Liu, Kenian, Wang, Michelle, Gao, Jing, Li, Tao, Xu, Mousheng, Silva, Ariosto S., Lee, Kaplan, Zhang, Tinghu, Koomen, John M., Jiang, Huijuan, Sudalagunta, Praneeth R., Meads, Mark B., Cheng, Fengdong, Bi, Chengfeng, Fu, Kai, Fan, Huitao, Dalton, William S., Moscinski, Lynn C., Shain, Kenneth H., Sotomayor, Eduardo M., Wang, Gang Greg, Gray, Nathanael S., Cleveland, John L., Qi, Jun, Tao, Jianguo

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Acid ceramidase controls proteasome inhibitor resistance and is a novel therapeutic target for the treatment of relapsed / refractory multiple myeloma von Bishop, Ryan T, Li, Tao, Sudalagunta, Praneeth, Nasr, Mostafa, Nyman, Karl J, Alugubelli, Raghunandan R, Meads, Mark, Frieling, Jeremy, Nerlakanti, Niveditha, Tauro, Marilena, Fang, Bin, Grant, Steven, Koomen, John, Silva, Ariosto S, Shain, Kenneth H, Lynch, Conor C

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PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas von Ren, Yuan, Bi, Chengfeng, Zhao, Xiaohong, Lwin, Tint, Wang, Cheng, Yuan, Ji, Silva, Ariosto S, Shah, Bijal D, Fang, Bin, Li, Tao, Koomen, John M, Jiang, Huijuan, Chavez, Julio C, Pham, Lan V, Sudalagunta, Praneeth R, Wan, Lixin, Wang, Xuefeng, Dalton, William S, Moscinski, Lynn C, Shain, Kenneth H, Vose, Julie, Cleveland, John L, Sotomayor, Eduardo M, Fu, Kai, Tao, Jianguo

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A theoretical quantitative model for evolution of cancer chemotherapy resistance von Silva, Ariosto S, Gatenby, Robert A

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Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma von Tantawy, Marwa, Yang, Guang, Algubelli, Raghunandan Reddy, DeAvila, Gabriel, Rubinstein, Samuel M, Cornell, Robert F, Fradley, Michael G, Siegel, Erin M, Hampton, Oliver A, Silva, Ariosto S, Lenihan, Daniel, Shain, Kenneth H, Baz, Rachid C, Gong, Yan

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Combined MEK1/2 and ATR inhibition promotes myeloma cell death through a STAT3‐dependent mechanism in vitro and in vivo von Li, Lin, Hu, Xiaoyan, Nkwocha, Jewel, Kmieciak, Maciej, Meads, Mark B., Shain, Kenneth H., Alugubelli, Raghunandan R., Silva, Ariosto S., Mann, Hashim, Sudalagunta, Praneeth R., Canevarolo, Rafael R., Zhou, Liang, Grant, Steven

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A statistical mechanics framework for Bayesian deep neural networks beyond the infinite-width limit von Pacelli, R., Ariosto, S., Pastore, M., Ginelli, F., Gherardi, M., Rotondo, P.

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CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma von Burger, Karen L, Fernandez, Mario R, Meads, Mark B, Sudalagunta, Praneeth, Oliveira, Paula S, Renatino Canevarolo, Rafael, Alugubelli, Raghunandan Reddy, Tungsevik, Alexandre, De Avila, Gabe, Silva, Maria, Graeter, Allison I, Dai, Hongyue A, Vincelette, Nicole D, Prabhu, Antony, Magaletti, Dario, Yang, Chunying, Li, Weimin, Kulkarni, Amit, Hampton, Oliver, Koomen, John M, Roush, William R, Monastyrskyi, Andrii, Berglund, Anders E, Silva, Ariosto S, Cleveland, John L, Shain, Kenneth H

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CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation von Jiang, Qibing, Sudalagunta, Praneeth, Silva, Maria C, Canevarolo, Rafael R, Zhao, Xiaohong, Ahmed, Khandakar Tanvir, Alugubelli, Raghunandan Reddy, DeAvila, Gabriel, Tungesvik, Alexandre, Perez, Lia, Gatenby, Robert A, Gillies, Robert J, Baz, Rachid, Meads, Mark B, Shain, Kenneth H, Silva, Ariosto S, Zhang, Wei

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Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma von Hasipek, Metis, Grabowski, Dale, Guan, Yihong, Alugubelli, Raghunandan Reddy, Tiwari, Anand D., Gu, Xiaorong, DeAvila, Gabriel A., Silva, Ariosto S., Meads, Mark B., Parker, Yvonne, Lindner, Daniel J., Saunthararajah, Yogen, Shain, Kenneth H., Maciejewski, Jaroslaw P., Reu, Frederic J., Phillips, James G., Jha, Babal K.

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A Preclinical Assay for Chemosensitivity in Multiple Myeloma von KHIN, Zayar P, RIBEIRO, Maria L. C, JACOBSON, Timothy, HAZLEHURST, Lori, PEREZ, Lia, BAZ, Rachid, SHAIN, Kenneth, SILVA, Ariosto S

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Metabolic Changes Are Associated with Melphalan Resistance in Multiple Myeloma von Koomen, David C, Meads, Mark B, Magaletti, Dario M, Guingab-Cagmat, Joy D, Oliveira, Paula S, Fang, Bin, Liu, Min, Welsh, Eric A, Meke, Laurel E, Jiang, Zhijie, Hampton, Oliver A, Tungesvik, Alexandre, De Avila, Gabriel, Alugubelli, Raghunandan Reddy, Nishihori, Taiga, Silva, Ariosto S, Eschrich, Steven A, Garrett, Timothy J, Koomen, John M, Shain, Kenneth H

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A pharmacodynamic model of clinical synergy in multiple myeloma von Sudalagunta, Praneeth, Silva, Maria C., Canevarolo, Rafael R., Alugubelli, Raghunandan Reddy, DeAvila, Gabriel, Tungesvik, Alexandre, Perez, Lia, Gatenby, Robert, Gillies, Robert, Baz, Rachid, Meads, Mark B., Shain, Kenneth H., Silva, Ariosto S.

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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma von Zhao, Xiaohong, Wang, Michelle Y., Jiang, Huijuan, Lwin, Tint, Park, Paul M., Gao, Jing, Meads, Mark B., Ren, Yuan, Li, Tao, Sun, Jiao, Fahmi, Naima Ahmed, Singh, Satishkumar, Sehgal, Lalit, Wang, Xuefeng, Silva, Ariosto S., Sotomayor, Eduardo M., Shain, Kenneth H., Cleveland, John L., Wang, Michael, Zhang, Wei, Qi, Jun, Shah, Bijal D., Tao, Jianguo

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Universal mean-field upper bound for the generalization gap of deep neural networks von Ariosto, S., Pacelli, R., Ginelli, F., Gherardi, M., Rotondo, P.

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Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma von Peres, Lauren C., Colin-Leitzinger, Christelle M., Teng, Mingxiang, Dutil, Julie, Alugubelli, Raghunandan R., DeAvila, Gabriel, Teer, Jamie K., Du, Dongliang, Mo, Qianxing, Siegel, Erin M., Hampton, Oliver A., Alsina, Melissa, Brayer, Jason, Blue, Brandon, Baz, Rachid, Silva, Ariosto S., Nishihori, Taiga, Shain, Kenneth H., Gillis, Nancy

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