Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy von Lequeux, Audrey, Noman, Muhammad Zaeem, Xiao, Malina, Van Moer, Kris, Hasmim, Meriem, Benoit, Alice, Bosseler, Manon, Viry, Elodie, Arakelian, Tsolere, Berchem, Guy, Chouaib, Salem, Janji, Bassam

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Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner von Mgrditchian, Takouhie, Arakelian, Tsolere, Paggetti, Jérôme, Noman, Muhammad Zaeem, Viry, Elodie, Moussay, Etienne, Van Moer, Kris, Kreis, Stephanie, Guerin, Coralie, Buart, Stephanie, Robert, Caroline, Borg, Christophe, Vielh, Philippe, Chouaib, Salem, Berchem, Guy, Janji, Bassam

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A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control von Tondini, Elena, Arakelian, Tsolere, Oosterhuis, Koen, Camps, Marcel, van Duikeren, Suzanne, Han, Wanda, Arens, Ramon, Zondag, Gerben, van Bergen, Jeroen, Ossendorp, Ferry

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T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors von Middelburg, Jim, Sluijter, Marjolein, Schaap, Gaby, Göynük, Büşra, Lloyd, Katy, Ovcinnikovs, Vitalijs, Zom, Gijs G., Marijnissen, Renoud J., Groeneveldt, Christianne, Griffioen, Lisa, Sandker, Gerwin G. W., Heskamp, Sandra, van der Burg, Sjoerd H., Arakelian, Tsolere, Ossendorp, Ferry, Arens, Ramon, Schuurman, Janine, Kemper, Kristel, van Hall, Thorbald

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Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet von Viry, Elodie, Noman, Muhammad Zaeem, Arakelian, Tsolère, Lequeux, Audrey, Chouaib, Salem, Berchem, Guy, Moussay, Etienne, Paggetti, Jérôme, Janji, Bassam

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Neoantigen-specific T cell help outperforms non-specific help in multi-antigen DNA vaccination against cancer von de Graaf, Joanna Fréderique, Pesic, Tamara, Spitzer, Felicia S, Oosterhuis, Koen, Camps, Marcel G M, Zoutendijk, Iris, Teunisse, Bram, Zhu, Wahwah, Arakelian, Tsolere, Zondag, Gerben C, Arens, Ramon, van Bergen, Jeroen, Ossendorp, Ferry

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770 Personalized synthetic polyepitope DNA cancer vaccines encoding a novel pyroptotic adjuvant to generate effective anti-tumor T cell immunity von Bergen, Jeroen Van, Arakelian, Tsolere, Moharana, Kedar, Teunisse, Bram, Zoutendijk, Iris, Camps, Marcel, Arens, Ramon, Ossendorp, Ferry, Zondag, Gerben

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Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control von Tondini, Elena, Reintjens, Niels R. M., Castello, Giulia, Arakelian, Tsolere, Isendoorn, Marjolein, Camps, Marcel, Vree, Jana, van der Marel, Gijs A., Filippov, Dmitri V., Codee, Jeroen D. C., Ossendorp, Ferry

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The multifaceted role of autophagy in tumor evasion from immune surveillance von Janji, Bassam, Viry, Elodie, Moussay, Etienne, Paggetti, Jérôme, Arakelian, Tsolère, Mgrditchian, Takouhie, Messai, Yosra, Noman, Muhammad Zaeem, Van Moer, Kris, Hasmim, Meriem, Mami-Chouaib, Fathia, Berchem, Guy, Chouaib, Salem

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Pyroptosis-inducing active caspase-1 as a genetic adjuvant in anti-cancer DNA vaccination von Arakelian, Tsolere, Oosterhuis, Koen, Tondini, Elena, Los, Mandy, Vree, Jana, van Geldorp, Mariska, Camps, Marcel, Teunisse, Bram, Zoutendijk, Iris, Arens, Ramon, Zondag, Gerben, Ossendorp, Ferry, van Bergen, Jeroen

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Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy von Noman, Muhammad Zaeem, Parpal, Santiago, Van Moer, Kris, Xiao, Malina, Yu, Yasmin, Viklund, Jenny, De Milito, Angelo, Hasmim, Meriem, Andersson, Martin, Amaravadi, Ravi K., Martinsson, Jessica, Berchem, Guy, Janji, Bassam

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Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy (vol 6, eaax7881, 2020) von Noman, Muhammad Zaeem, Parpal, Santiago, Van Moer, Kris, Xiao, Malina, Yu, Yasmin, Arakelian, Tsolere, Viklund, Jenny, De Milito, Angelo, Hasmim, Meriem, Andersson, Martin, Amaravadi, Ravi K., Martinsson, Jessica, Berchem, Guy, Janji, Bassam

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Hijacker of the anti-tumor immune response: autophagy is showing its worst facet von Elodie Viry, Muhammad Zaeem Noman, Tsolere Arakelian, Audrey Lequeux, Salem Chouaib, Guy Berchem, Guy Berchem, Etienne Moussay, Jerome Paggetti, Bassam Janji

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0441: Bcl11b/CTIP2, a newly identified transcriptional repressor: its role in cardiac hypertrophy and commitment of cardiac stem cells von El-Koury, Roy, Riclet, Raphael, Arakelian, Tsolère, Zhenlin, Li, Rohr, Olivier, Bausero, Pedro, Parlakian, Ara

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Autophagy Regulation of the Tumor Immunity – An Old Machinery for a New Function von Arakelian, Tsolere

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