Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor von Muratspahić, Edin, Deibler, Kristine, Han, Jianming, Tomašević, Nataša, Jadhav, Kirtikumar B., Olivé-Marti, Aina-Leonor, Hochrainer, Nadine, Hellinger, Roland, Koehbach, Johannes, Fay, Jonathan F., Rahman, Mohammad Homaidur, Hegazy, Lamees, Craven, Timothy W., Varga, Balazs R., Bhardwaj, Gaurav, Appourchaux, Kevin, Majumdar, Susruta, Muttenthaler, Markus, Hosseinzadeh, Parisa, Craik, David J., Spetea, Mariana, Che, Tao, Baker, David, Gruber, Christian W.

Volltext

Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR von Ople, Rohini S., Ramos-Gonzalez, Nokomis, Li, Qiongyu, Sobecks, Briana L., Aydin, Deniz, Powers, Alexander S., Faouzi, Abdelfattah, Polacco, Benjamin J., Bernhard, Sarah M., Appourchaux, Kevin, Sribhashyam, Sashrik, Eans, Shainnel O., Tsai, Bowen A., Dror, Ron O., Varga, Balazs R., Wang, Haoqing, Hüttenhain, Ruth, McLaughlin, Jay P., Majumdar, Susruta

Volltext

IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C von Estrabaud, Emilie, Appourchaux, Kevin, Bièche, Ivan, Carrat, Fabrice, Lapalus, Martine, Lada, Olivier, Martinot-Peignoux, Michelle, Boyer, Nathalie, Marcellin, Patrick, Vidaud, Michel, Asselah, Tarik

Volltext

Predicted Mode of Binding to and Allosteric Modulation of the μ‑Opioid Receptor by Kratom’s Alkaloids with Reported Antinociception In Vivo von Zhou, Yuchen, Ramsey, Steven, Provasi, Davide, El Daibani, Amal, Appourchaux, Kevin, Chakraborty, Soumen, Kapoor, Abhijeet, Che, Tao, Majumdar, Susruta, Filizola, Marta

Volltext

Structure-based design of bitopic ligands for the µ-opioid receptor von Faouzi, Abdelfattah, Wang, Haoqing, Zaidi, Saheem A., DiBerto, Jeffrey F., Che, Tao, Qu, Qianhui, Robertson, Michael J., Madasu, Manish K., El Daibani, Amal, Varga, Balazs R., Zhang, Tiffany, Ruiz, Claudia, Liu, Shan, Xu, Jin, Appourchaux, Kevin, Slocum, Samuel T., Eans, Shainnel O., Cameron, Michael D., Al-Hasani, Ream, Pan, Ying Xian, Roth, Bryan L., McLaughlin, Jay P., Skiniotis, Georgios, Katritch, Vsevolod, Kobilka, Brian K., Majumdar, Susruta

Volltext

Structure, Function, and Pharmacology of Delta Opioid Receptor Bitopics von Bernhard, Sarah, Varga, Balazs R., Daibani, Amal El, Lam, Jordy H., Zaidi, Saheem, Appourchaux, Kevin, Eans, Shainnel, Katritch, Vsevolod, McLaughlin, Jay, Majumdar, Susruta, Che, Tao

Volltext

Structure based approaches on fentanyl template to design novel mu opioid modulators von Ople, Rohini, Wang, Haoqing, Li, Qiongyu, Polacco, Ben, Bernhard, Sarah, Appourchaux, Kevin, Sribhashyam, Sashrik, Eans, Shainnel, Huttenhain, Ruth, McLaughlin, Jay, Kobilka, Brian, Majumdar, Susruta

Volltext

Negative allosteric modulation of the µ-opioid receptor von O'Brien, Evan S., Rangari, Vipin A., El Daibani, Amal, Eans, Shainnel O., White, Betsy, Wang, Haoqing, Shiimura, Yuki, Kumar, Kaavya Krishna, Appourchaux, Kevin, Zhang, Chensong, Mathiesen, Jesper M., Che, Tao, McLaughlin, Jay P., Majumdar, Susruta, Kobilka, Brian K.

Volltext

A µ-opioid receptor modulator that works cooperatively with naloxone von O’Brien, Evan S., Rangari, Vipin Ashok, El Daibani, Amal, Eans, Shainnel O., Hammond, Haylee R., White, Elizabeth, Wang, Haoqing, Shiimura, Yuki, Krishna Kumar, Kaavya, Jiang, Qianru, Appourchaux, Kevin, Huang, Weijiao, Zhang, Chensong, Kennedy, Brandon J., Mathiesen, Jesper M., Che, Tao, McLaughlin, Jay P., Majumdar, Susruta, Kobilka, Brian K.

Volltext

MicroRNA-based diagnostic tools for advanced fibrosis and cirrhosis in patients with chronic hepatitis B and C von Appourchaux, Kevin, Dokmak, Safi, Resche-Rigon, Matthieu, Treton, Xavier, Lapalus, Martine, Gattolliat, Charles-Henry, Porchet, Emmanuelle, Martinot-Peignoux, Michelle, Boyer, Nathalie, Vidaud, Michel, Bedossa, Pierre, Marcellin, Patrick, Bièche, Ivan, Estrabaud, Emilie, Asselah, Tarik

Volltext

Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor von Hennessy, Madeline R., Gutridge, Anna M., French, Alexander R., Rhoda, Elizabeth S., Meqbil, Yazan J., Gill, Meghna, Kashyap, Yavnika, Appourchaux, Kevin, Paul, Barnali, Wang, Zaijie Jim, van Rijn, Richard M., Riley, Andrew P.

Volltext

Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists von Griffett, Kristine, Hayes, Matthew, Bedia-Diaz, Gonzalo, Appourchaux, Kevin, Sanders, Ryan, Boeckman, Michael P., Koelblen, Thomas, Zhang, Jinsong, Schulman, Ira G., Elgendy, Bahaa, Burris, Thomas P.

Volltext

Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom von Chakraborty, Soumen, Uprety, Rajendra, Daibani, Amal E, Rouzic, Valerie L, Hunkele, Amanda, Appourchaux, Kevin, Eans, Shainnel O, Nuthikattu, Nitin, Jilakara, Rahul, Thammavong, Lisa, Pasternak, Gavril W, Pan, Ying-Xian, McLaughlin, Jay P, Che, Tao, Majumdar, Susruta

Volltext

Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc−/− Mice von Reimann, Christian, Six, Emmanuelle, Dal-Cortivo, Liliane, Schiavo, Andrea, Appourchaux, Kevin, Lagresle-Peyrou, Chantal, de Chappedelaine, Corinne, Ternaux, Brigitte, Coulombel, Laure, Beldjord, Kheira, Cavazzana-Calvo, Marina, Andre-Schmutz, Isabelle

Volltext

Generation of adult human T-cell progenitors for immunotherapeutic applications von Simons, Laura, Ma, Kuiying, de Chappedelaine, Corinne, Moiranghtem, Ranjita Devi, Elkaim, Elodie, Olivré, Juliette, Susini, Sandrine, Appourchaux, Kevin, Reimann, Christian, Sadek, Hanem, Pellé, Olivier, Cagnard, Nicolas, Magrin, Elisa, Lagresle-Peyrou, Chantal, Taghon, Tom, Rausell, Antonio, Cavazzana, Marina, André-Schmutz, Isabelle

Volltext

Reduction of microRNA 122 expression in IFNL3 CT/TT carriers and during progression of fibrosis in patients with chronic hepatitis C von Estrabaud, Emilie, Lapalus, Martine, Broët, Philippe, Appourchaux, Kevin, De Muynck, Simon, Lada, Olivier, Martinot-Peignoux, Michelle, Bièche, Ivan, Valla, Dominique, Bedossa, Pierre, Marcellin, Patrick, Vidaud, Michel, Asselah, Tarik

Volltext

Generation of adult human T-cell progenitors for immunotherapeutic applications von Simons, Laura, Ma, Kuiying, de Chappedelaine, Corinne, Moiranghtem, Ranjita Devi, Elkaim, Elodie, Olivré, Juliette, Susini, Sandrine, Appourchaux, Kevin, Reimann, Christian, Sadek, Hanem, Pellé, Olivier, Cagnard, Nicolas, Magrin, Elisa, Lagresle-Peyrou, Chantal, Taghon, Tom, Rausell, Antonio, Cavazzana, Marina, André-Schmutz, Isabelle

Volltext

Precore/Core promoter variants to predict significant fibrosis in both HBeAg positive and negative chronic hepatitis B von Lapalus, Martine, Laouenan, Cédric, Cardoso, Ana-Carolina, Estrabaud, Emilie, Carvalho-Filho, Roberto J., Zhang, Qian, Lada, Olivier, Appourchaux, Kevin, Mouri, Feryel, Boyer, Nathalie, Bedossa, Pierre, Asselah, Tarik, Martinot-Peignoux, Michelle, Marcellin, Patrick

Volltext

Precore/Core promoter variants to predict significant fibrosis in both HB eAg positive and negative chronic hepatitis B von Lapalus, Martine, Laouenan, Cédric, Cardoso, Ana‐Carolina, Estrabaud, Emilie, Carvalho‐Filho, Roberto J., Zhang, Qian, Lada, Olivier, Appourchaux, Kevin, Mouri, Feryel, Boyer, Nathalie, Bedossa, Pierre, Asselah, Tarik, Martinot‐Peignoux, Michelle, Marcellin, Patrick

Volltext

Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/[gamma]c-/- Mice von Reimann, Christian, Six, Emmanuelle, Dal-Cortivo, Liliane, Schiavo, Andrea, Appourchaux, Kevin, Lagresle-Peyrou, Chantal, de Chappedelaine, Corinne, Ternaux, Brigitte, Coulombel, Laure, Beldjord, Kheira, Cavazzana-Calvo, Marina, Andre-Schmutz, Isabelle

Volltext