Characterization of HKI-272 Covalent Binding to Human Serum Albumin von JIANYAO WANG, LI-CHAN, Xiao Xian, CHANDRASEKARAN, Appavu, OGANESIAN, Aram, SCATINA, Joann, MUTLIB, Abdul, TALAAT, Rasmy, ATHERTON, Jim, LIN DENG, ESPINA, Robert, LINNING YU, HORWATT, Peter, ROSS, Steven, LOCKHEAD, Susan, AHMAD, Syed

Volltext

Metabolic Disposition of [14C]Bazedoxifene in Healthy Postmenopausal Women von Chandrasekaran, Appavu, McKeand, William E., Sullivan, Pamela, DeMaio, William, Stoltz, Randall, Scatina, JoAnn

Volltext

Effects of pethoxamid treatment on the disposition of thyroxine in rats von Chandrasekaran, Appavu, Bentley, Karin, McClanahan, Robert, Nallani, Gopinath

Volltext

Molecular and Pharmacological Properties of a Potent and Selective Novel Nonsteroidal Progesterone Receptor Agonist Tanaproget von Zhang, Zhiming, Olland, Andrea M, Zhu, Yuan, Cohen, Jeff, Berrodin, Tom, Chippari, Susan, Appavu, Chandrasekaran, Li, Shen, Wilhem, James, Chopra, Raj, Fensome, Andrew, Zhang, Puwen, Wrobel, Jay, Unwalla, Rayomand J, Lyttle, C Richard, Winneker, Richard C

Volltext

Toxicokinetic testing strategies to demonstrate bone marrow exposure in in vivo micronucleus study for genotoxicity assessment of agrochemicals von Nallani, Gopinath C., Liu, Zhiwei, Chandrasekaran, Appavu

Volltext

Determination of offspring NOAEL for zeta-cypermethrin using internal exposure data from rat developmental neurotoxicity studies von Liu, Zhiwei, Chandrasekaran, Appavu, Becker, John M

Volltext

The pharmacokinetic properties of bifenthrin in the rat following multiple routes of exposure von Gammon, Derek, Liu, Zhiwei, Chandrasekaran, Appavu, ElNaggar, Shaaban

Volltext

Age dependent in vitro metabolism of bifenthrin in rat and human hepatic microsomes von Nallani, Gopinath C., Chandrasekaran, Appavu, Kassahun, Kelem, Shen, Li, ElNaggar, Shaaban F., Liu, Zhiwei

Volltext

Establishing maximum tolerated doses for a 2-year combined chronic/carcinogenicity rat study based on toxicokinetic and toxicity gender differences von Liu, Zhiwei, Wasniewski, Amanda, Lamperti, Sara, Mainolfi, Katia, Chandrasekaran, Appavu

Volltext

Pyrethroid neurotoxicity studies with bifenthrin indicate a mixed Type I/II mode of action von Gammon, Derek W, Liu, Zhiwei, Chandrasekaran, Appavu, El‐Naggar, Shaaban F, Kuryshev, Yuri A, Jackson, Sharon

Volltext

In vitro metabolism of [14C]-benalaxyl in hepatocytes of rats, dogs and humans von Nallani, Gopinath C., ElNaggar, Shaaban F., Shen, Li, Chandrasekaran, Appavu

Volltext

Locomotor activity and tissue levels following acute administration of lambda- and gamma-cyhalothrin in rats von Moser, Virginia C., Liu, Zhiwei, Schlosser, Christopher, Spanogle, Terri L., Chandrasekaran, Appavu, McDaniel, Katherine L.

Volltext

Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine (19F) Nuclear Magnetic Resonance (NMR) Spectroscopy in M... von Mutlib, Abdul, Espina, Robert, Atherton, James, Wang, Jianyao, Talaat, Rasmy, Scatina, JoAnn, Chandrasekaran, Appavu

Volltext

In vitro metabolism, permeability, and efflux of bazedoxifene in humans von Shen, Li, Ahmad, Syed, Park, SeongHee, DeMaio, William, Oganesian, Aram, Hultin, Theresa, Scatina, JoAnn, Bungay, Peter, Chandrasekaran, Appavu

Volltext

Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine ( super(19)F) Nuclear Magnetic Resonance (NMR) Spectrosc... von Mutlib, Abdul, Espina, Robert, Atherton, James, Wang, Jianyao, Talaat, Rasmy, Scatina, JoAnn, Chandrasekaran, Appavu

Volltext

In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone von Tong, Zeen, Chandrasekaran, Appavu, Li, Hongshan, Rotshteyn, Yakov, Erve, John C L, Demaio, William, Talaat, Rasmy, Hultin, Theresa, Scatina, JoAnn

Volltext

Species Differences in the Formation of Vabicaserin Carbamoyl Glucuronide von TONG, Zeen, CHANDRASEKARAN, Appavu, DEMAIO, William, JORDAN, Ronald, HONGSHAN LI, MOORE, Robin, POOLA, Nagaraju, BURGHART, Peter, HULTIN, Theresa, SCATINA, Joann

Volltext

Metabolism of Intravenous Methylnaltrexone in Mice, Rats, Dogs, and Humans von CHANDRASEKARAN, Appavu, TONG, Zeen, SCATINA, Joann, HONGSHAN LI, ERVE, John C. L, DEMAIO, William, GOLJER, Igor, MCCONNELL, Oliver, ROTSHTEYN, Yakov, HULTIN, Theresa, TALAAT, Rasmy

Volltext

Metabolism of Vabicaserin in Mice, Rats, Dogs, Monkeys, and Humans von ZEEN TONG, CHANDRASEKARAN, Appavu, DEMAIO, William, ESPINA, Robert, WEI LU, JORDAN, Ronald, SCATINA, Joann

Volltext

In Vitro Metabolism and Identification of Human Enzymes Involved in the Metabolism of Methyinaltrexone von TONG, Zeen, CHANDRASEKARAN, Appavu, HONGSHAN LI, ROTSHTEYN, Yakov, ERVE, John C. L, DEMAIO, William, TALAAT, Rasmy, HULTIN, Theresa, SCATINA, Joann

Volltext