Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis von Ratnayake, Wishrawana S, Apostolatos, André H, Ostrov, David A, Acevedo-Duncan, Mildred

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Identification of a Novel Antiapoptotic Human Protein Kinase C δ Isoform, PKCδVIII in NT2 Cells von Jiang, Kun, Apostolatos, André H, Ghansah, Tomar, Watson, James E, Vickers, Timothy, Cooper, Denise R, Epling-Burnette, P. K, Patel, Niketa A

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Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade von Apostolatos, Andr, Ratnayake, Wishrawana, Win-Piazza, Hla, Apostolatos, Christopher, Smalley, Tracess, Kang, Loveleen, Salup, Raoul, Hill, Robert, Acevedo-Duncan, Mildred

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Abstract 179: Atypical protein kinase C inhibition in prostate cancer cells: a study of ICA-1 and ACPD von Apostolatos, Andre H.

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Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors von Ratnayake, Wishrawana S., Apostolatos, Christopher A., Apostolatos, André H., Schutte, Ryan J., Huynh, Monica A., Ostrov, David A., Acevedo-Duncan, Mildred

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Abstract 2542: c-Jun and FOXO1 play key roles in the overexpression of oncogenic PKC-ι in human prostate and melanoma cell lines von Apostolatos, Andre H., Ratnayake, Wishrawana S., Islam, Anisul, Apostolatos, Christopher, Smalley, Tracess, Acevedo-Duncan, Mildred

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Abstract 5868: Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide (ICA-1): A potent protein kinase C-ι inhibitor as a pot... von Apostolatos, Christopher, Apostolatos, Andre H., Ratnayake, Wishrawana S., Bourgeois, Marie, Acevedo-Duncan, Mildred

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Abstract 3470: Atypical protein kinase C inhibition in prostate cancer cells: A study of ICA-1 and ACPD von Apostolatos, Andre H., Apostolatos, Christopher, Acevedo-Duncan, Mildred

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Abstract 2369: Transcription activators that regulate PKC-iota expression and are downstream targets of PKC-iota von Apostolatos, Andre H., Ratnayake, Wishrawana S., Smalley, Tracess, Islam, Anisul, Acevedo-Duncan, Mildred

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Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver von Sajan, Mini P., Braun, Ursula, Leitges, Michael, Park, Colin, Diamond, David M., Wu, Jin, Hansen, Barbara C., Duncan, Mildred Acevedo, Apostolatos, Christopher A., Apostolatos, Andre H., Kindy, Mark, Farese, Robert V.

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FOXO1 regulates oncogenic PKC-[iota] expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation von Ratnayake, Wishrawana S, Apostolatos, Christopher A, Breedy, Sloan, Apostolatos, Andre H, Acevedo-Duncan, Mildred

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Abstract 2022: Oncogenic protein kinase Cι drives melanoma cell epithelial-mesenchymal transition by activating vimentin through Par6/RhoA signaling von Ratnayake, Wishrawana S., Apostolatos, André H., Apostolatos, Christopher A., Dey, Avijit, Patel, Rekha, Acevedo-Duncan, Mildred

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Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells von Jiang, Kun, Apostolatos, André H, Ghansah, Tomar, Watson, James E, Vickers, Timothy, Cooper, Denise R, Epling-Burnette, P K, Patel, Niketa A

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Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes von Carter, Gay, Apostolatos, André, Patel, Rekha, Mathur, Abhishek, Cooper, Denise, Murr, Michel, Patel, Niketa A.

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