Activation of Human MutS Homologs by 8-Oxo-guanine DNA Damage von Mazurek, Anthony, Berardini, Mark, Fishel, Richard

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Reversible suppression of an essential gene in adult mice using transgenic RNA interference von McJunkin, Katherine, Mazurek, Anthony, Premsrirut, Prem K., Zuber, Johannes, Dow, Lukas E., Simon, Janelle, Stillman, Bruce, Lowe, Scott W.

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Sequence Context Effect for hMSH2-hMSH6 Mismatch-Dependent Activation von Mazurek, Anthony, Johnson, Christopher N., Germann, Markus W., Fishel, Richard, Kolodner, Richard D.

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Acquired Dependence of Acute Myeloid Leukemia on the DEAD-Box RNA Helicase DDX5 von Mazurek, Anthony, Park, Youngkyu, Miething, Cornelius, Wilkinson, John E., Gillis, Jesse, Lowe, Scott W., Vakoc, Christopher R., Stillman, Bruce

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DNA Mismatch Repair-dependent Response to Fluoropyrimidine-generated Damage von Meyers, Mark, Wagner, Mark W., Mazurek, Anthony, Schmutte, Christoph, Fishel, Richard, Boothman, David A.

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Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells von Warth, Benedikt, Palermo, Amelia, Rattray, Nicholas J W, Lee, Nathan V, Zhu, Zhou, Hoang, Linh T, Cai, Yuping, Mazurek, Anthony, Dann, Stephen, VanArsdale, Todd, Fantin, Valeria R, Shields, David, Siuzdak, Gary, Johnson, Caroline H

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HNPCC mutations in hMSH2 result in reduced hMSH2-hMSH6 molecular switch functions von Heinen, Christopher D., Wilson, Teresa, Mazurek, Anthony, Berardini, Mark, Butz, Charles, Fishel, Richard

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Sustained mTORC1 activity during palbociclib-induced growth arrest triggers senescence in ER+ breast cancer cells von Maskey, Reeja S., Wang, Fang, Lehman, Elyssa, Wang, Yiqun, Emmanuel, Natasha, Zhong, Wenyan, Jin, Guixian, Abraham, Robert T., Arndt, Kim T., Myers, Jeremy S., Mazurek, Anthony

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DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells von Mazurek, Anthony, Luo, Weijun, Krasnitz, Alexander, Hicks, James, Powers, R Scott, Stillman, Bruce

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Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer von Sharma, Shikhar, Chung, Chi-Yeh, Uryu, Sean, Petrovic, Jelena, Cao, Joan, Rickard, Amanda, Nady, Nataliya, Greasley, Samantha, Johnson, Eric, Brodsky, Oleg, Khan, Showkhin, Wang, Hui, Wang, Zhenxiong, Zhang, Yong, Tsaparikos, Konstantinos, Chen, Lei, Mazurek, Anthony, Lapek, John, Kung, Pei-Pei, Sutton, Scott, Richardson, Paul F., Greenwald, Eric C., Yamazaki, Shinji, Jones, Rhys, Maegley, Karen A., Bingham, Patrick, Lam, Hieu, Stupple, Alexandra E., Kamal, Aileen, Chueh, Anderly, Cuzzupe, Anthony, Morrow, Benjamin J., Ren, Bin, Carrasco-Pozo, Catalina, Tan, Chin Wee, Bhuva, Dharmesh D., Allan, Elizabeth, Surgenor, Elliot, Vaillant, François, Pehlivanoglu, Havva, Falk, Hendrik, Whittle, James R., Newman, Janet, Cursons, Joseph, Doherty, Judy P., White, Karen L., MacPherson, Laura, Devlin, Mark, Dennis, Matthew L., Hattarki, Meghan K., De Silva, Melanie, Camerino, Michelle A., Butler, Miriam S., Dolezal, Olan, Pilling, Patricia, Foitzik, Richard, Stupple, Paul A., Lagiakos, H. Rachel, Walker, Scott R., Hediyeh-Zadeh, Soroor, Nuttall, Stewart, Spall, Sukhdeep K., Charman, Susan A., Connor, Theresa, Peat, Thomas S., Avery, Vicky M., Bozikis, Ylva E., Yang, Yuqing, Zhang, Ming, Monahan, Brendon J., Voss, Anne K., Thomas, Tim, Street, Ian P., Dawson, Sarah-Jane, Dawson, Mark A., Lindeman, Geoffrey J., Davis, Melissa J., Visvader, Jane E., Paul, Thomas A.

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Abstract 1637: MAT2A inhibition in MTAP-/- tumors confers mechanistic vulnerabilities to multiple clinically actionable synthetic lethal drug combinations von Gerrick, Kimberline Y., Laraio, Jenny, Annen, Kelsey, Tran, Hoang, Fischer, Marcus M., Freyman, Yevgeniy, Sharma, Geeta, Bishof, Isaac, Federowicz, Stephen, Pankajakshan, Divya, Neilan, Claire L., Mangatt, Biju, Mazurek, Anthony, Lackner, Mark R., White, Michael, Mounir, Zineb

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The Effect of O6-Methylguanine DNA Adducts on the Adenosine Nucleotide Switch Functions of hMSH2-hMSH6 and hMSH2-hMSH3 von Berardini, M, Mazurek, A, Fishel, R

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Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1 von QIANG WANG, HONGTAO ZHANG, GUERRETTE, Shawn, JINQIU CHEN, MAZUREK, Anthony, WILSON, Teresa, SLUPIANEK, Artur, SKORSKI, Tomasz, FISHEL, Richard, GREENE, Mark I

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COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A TOPOISOMERASE INHIBITOR, A SPLICING INHIBITOR SULFONAMIDE, OR A KIF18 INHIBITOR von FISCHER, Marcus M, NEILAN, Claire L, GERRICK, Kimberline Yang, LARAIO, Jenny Leigh, MAZUREK, Anthony

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Interaction of Alcohols and Anesthetics with Protein Kinase Cα von Slater, Simon J., Kelly, Mary Beth, Larkin, Jonathan D., Ho, Cojen, Mazurek, Anthony, Taddeo, Frank J., Yeager, Mark D., Stubbs, Christopher D.

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COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A PARP INHIBITOR von ANNEN, Kelsey Elizabeth, NEILAN, Claire L, FISCHER, Marcus Michael, LARAIO, Jenny Leigh, MAZUREK, Anthony

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COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND AN ANTIMETABOLITE AGENT von SHARMA, Geeta, NEILAN, Claire L, FISCHER, Marcus Michael, GERRICK, Kimberline Yang, LARAIO, Jenny Leigh, MAZUREK, Anthony

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KAT6 INHIBITOR METHODS AND COMBINATIONS FOR CANCER TREATMENT von ZHONG, Wenyan, CHEN, Lei, FRUHLING, David Scott, FOLLETTIE, Maximillian Todd, STUPPLE, Paul Anthony, TEDESCHI, Philip Michael, KUNG, Pei-Pei, ARNDT, Kim Timothy, MAZUREK, Anthony

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Inhibition of Membrane Lipid-independent Protein Kinase Cα Activity by Phorbol Esters, Diacylglycerols, and Bryostatin-1 von Slater, Simon J., Taddeo, Frank J., Mazurek, Anthony, Stagliano, Brigid A., Milano, Shawn K., Kelly, Mary Beth, Ho, Cojen, Stubbs, Christopher D.

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KAT6 INHIBITOR METHODS AND COMBINATIONS FOR CANCER TREATMENT von ZHONG, Wenyan, CHEN, Lei, FRUHLING, David Scott, FOLLETTIE, Maximillian Todd, STUPPLE, Paul Anthony, TEDESCHI, Philip Michael, KUNG, Pei-Pei, ARNDT, Kim Timothy, MAZUREK, Anthony

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