Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids von van der Graaf, Adriaan, Claringbould, Annique, Rimbert, Antoine, Westra, Harm-Jan, Li, Yang, Wijmenga, Cisca, Sanna, Serena

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GRaNIE and GRaNPA: inference and evaluation of enhancer‐mediated gene regulatory networks von Kamal, Aryan, Arnold, Christian, Claringbould, Annique, Moussa, Rim, Servaas, Nila H, Kholmatov, Maksim, Daga, Neha, Nogina, Daria, Mueller‐Dott, Sophia, Reyes‐Palomares, Armando, Palla, Giovanni, Sigalova, Olga, Bunina, Daria, Pabst, Caroline, Zaugg, Judith B

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Gender differences in the mental health impact of the COVID-19 lockdown: Longitudinal evidence from the Netherlands von Vloo, A., Alessie, R.J.M., Mierau, J.O., Boezen, Marike H., Mierau, Jochen O., Franke, Lude, Dekens, Jackie, Deelen, Patrick, Lanting, Pauline, Vonk, Judith M., Nolte, Ilja, Ori, Anil P.S., Claringbould, Annique, Boulogne, Floranne, Dijkema, Marjolein X.L., Wiersma, Henry H., Warmerdam, Robert, Jankipersadsing, Soesma A.

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Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies von van Rooij, Jeroen, Mandaviya, Pooja R, Claringbould, Annique, Felix, Janine F, van Dongen, Jenny, Jansen, Rick, Franke, Lude, 't Hoen, Peter A C, Heijmans, Bas, van Meurs, Joyce B J

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Limited evidence for blood eQTLs in human sexual dimorphism von Porcu, Eleonora, Claringbould, Annique, Weihs, Antoine, Lepik, Kaido, Richardson, Tom G, Völker, Uwe, Santoni, Federico A, Teumer, Alexander, Franke, Lude, Reymond, Alexandre, Kutalik, Zoltán

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Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes von Urzúa-Traslaviña, Carlos G, van Lieshout, Tijs, Boulogne, Floranne, Domanegg, Kevin, Zidan, Mahmoud, Bakker, Olivier B, Claringbould, Annique, de Ridder, Jeroen, Zwart, Wilbert, Westra, Harm-Jan, Deelen, Patrick, Franke, Lude

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GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI von Couto Alves, Alexessander, De Silva, N Maneka G, Karhunen, Ville, Sovio, Ulla, Das, Shikta, Taal, H Rob, Warrington, Nicole M, Lewin, Alexandra M, Kaakinen, Marika, Cousminer, Diana L, Thiering, Elisabeth, Timpson, Nicholas J, Bond, Tom A, Lowry, Estelle, Brown, Christopher D, Estivill, Xavier, Lindi, Virpi, Bradfield, Jonathan P, Geller, Frank, Speed, Doug, Coin, Lachlan J M, Loh, Marie, Barton, Sheila J, Beilin, Lawrence J, Bisgaard, Hans, Bønnelykke, Klaus, Alili, Rohia, Hatoum, Ida J, Schramm, Katharina, Cartwright, Rufus, Charles, Marie-Aline, Salerno, Vincenzo, Clément, Karine, Claringbould, Annique A J, van Duijn, Cornelia M, Moltchanova, Elena, Eriksson, Johan G, Elks, Cathy, Feenstra, Bjarke, Flexeder, Claudia, Franks, Stephen, Frayling, Timothy M, Freathy, Rachel M, Elliott, Paul, Widén, Elisabeth, Hakonarson, Hakon, Hattersley, Andrew T, Rodriguez, Alina, Banterle, Marco, Heinrich, Joachim, Heude, Barbara, Holloway, John W, Hofman, Albert, Hyppönen, Elina, Inskip, Hazel, Kaplan, Lee M, Hedman, Asa K, Läärä, Esa, Prokisch, Holger, Grallert, Harald, Lakka, Timo A, Lawlor, Debbie A, Melbye, Mads, Ahluwalia, Tarunveer S, Marinelli, Marcella, Millwood, Iona Y, Palmer, Lyle J, Pennell, Craig E, Perry, John R, Ring, Susan M, Savolainen, Markku J, Rivadeneira, Fernando, Standl, Marie, Sunyer, Jordi, Tiesler, Carla M T, Uitterlinden, Andre G, Schierding, William, O'Sullivan, Justin M, Prokopenko, Inga, Herzig, Karl-Heinz, Smith, George Davey, O'Reilly, Paul, Felix, Janine F, Buxton, Jessica L, Blakemore, Alexandra I F, Ong, Ken K, Jaddoe, Vincent W V, Grant, Struan F A, Sebert, Sylvain, McCarthy, Mark I, Järvelin, Marjo-Riitta

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Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease von van der Graaf, Adriaan, Zorro, Maria M, Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M, Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris

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Enhancers in disease: molecular basis and emerging treatment strategies von Claringbould, Annique, Zaugg, Judith B.

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Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks von Bakker, Olivier B., Claringbould, Annique, Westra, Harm-Jan, Wiersma, Henry, Boulogne, Floranne, Võsa, Urmo, Urzúa-Traslaviña, Carlos G., Mulcahy Symmons, Sophie, Zidan, Mahmoud M. M., Sadler, Marie C., Kutalik, Zoltán, Jonkers, Iris H., Franke, Lude, Deelen, Patrick

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Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations von Lepamets, Maarja, Auwerx, Chiara, Nõukas, Margit, Claringbould, Annique, Porcu, Eleonora, Kals, Mart, Jürgenson, Tuuli, Morris, Andrew Paul, Võsa, Urmo, Bochud, Murielle, Stringhini, Silvia, Wijmenga, Cisca, Franke, Lude, Peterson, Hedi, Vilo, Jaak, Lepik, Kaido, Mägi, Reedik, Kutalik, Zoltán

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences von Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Wu, Yang, Zhang, Futao, Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Urs, Groenen, Patrick J. F., Harris, Kathleen Mullan, Hasler, Gregor, Hofman, Albert, Ikram, Mohammad A., Jain, Sonia, Karlsson, Robert, Kessler, Ronald C., Kooyman, Maarten, MacKillop, James, Männikkö, Minna, Morcillo-Suarez, Carlos, McQueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthias, Thurik, A. Roy, Uitterlinden, André G., White, Jon, Wit, Harriet de, Yang, Jian, Bertram, Lars, Boomsma, Dorret I., Esko, Tõnu, Fehr, Ernst, Hinds, David A., Johannesson, Magnus, Kumari, Meena, Laibson, David, Magnusson, Patrik K. E., Meyer, Michelle N., Navarro, Arcadi, Palmer, Abraham A., Pers, Tune H., Posthuma, Danielle, Schunk, Daniel, Stein, Murray B., Svento, Rauli, Tiemeier, Henning, Timmers, Paul R. H. J., Turley, Patrick, Ursano, Robert J., Wagner, Gert G., Wilson, James F., Gratten, Jacob, Lee, James J., Cesarini, David, Benjamin, Daniel J., Koellinger, Philipp D., Beauchamp, Jonathan P.

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Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes von Xue, Angli, Wu, Yang, Zhu, Zhihong, Zhang, Futao, Kemper, Kathryn E., Zheng, Zhili, Yengo, Loic, Lloyd-Jones, Luke R., Sidorenko, Julia, Wu, Yeda, McRae, Allan F., Visscher, Peter M., Zeng, Jian, Yang, Jian

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood von Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F., Yang, Jian

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Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits von Porcu, Eleonora, Rüeger, Sina, Lepik, Kaido, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán

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HAPLOTYPE-BASED INFERENCE OF NON-TRANSMITTED ALLELES FOR ESTIMATION OF GENETIC NURTURE EFFECTS von Pons, Victória Trindade, Claringbould, Annique, Kamphuis, Priscilla, Oldehinkel, Albertine, van Loo, Hanna

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Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome von Zhernakova, Daria V., Le, Trang H., Kurilshikov, Alexander, Atanasovska, Biljana, Bonder, Marc Jan, Sanna, Serena, Claringbould, Annique, Võsa, Urmo, Deelen, Patrick, Franke, Lude, de Boer, Rudolf A., Kuipers, Folkert, Netea, Mihai G., Hofker, Marten H., Wijmenga, Cisca, Zhernakova, Alexandra, Fu, Jingyuan

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Using parent-offspring pairs and trios to estimate indirect genetic effects in education von Trindade Pons, Victória, Claringbould, Annique, Kamphuis, Priscilla, Oldehinkel, Albertine J, van Loo, Hanna M

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Sex and Gender-Related Differences in COVID-19 Diagnoses and SARS-CoV-2 Testing Practices During the First Wave of the Pandemic: The Dutch Lifelines COVID-19 Cohort Study von Ballering, Aranka Viviënne, Oertelt-Prigione, Sabine, Olde Hartman, Tim C, Rosmalen, Judith G M

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Increases in symptoms of depression and anxiety in adults during the initial phases of the COVID-19 pandemic are limited to those with less resources: Results from the Lifelines Co... von Qi, Yuwei, Lepe, Alexander, Almansa, Josué, Ots, Patricia, de Kroon, Marlou L.A., Boezen, H.M., Mierau, J.O., Franke, H.L., Dekens, J., Deelen, P., Lanting, Pauline, Vonk, Judith M., Nolte, Ilja, Ori, Anil P.S., Claringbould, Annique, Boulogne, Floranne, Dijkema, Marjolein X.L., Wiersma, Henry H., Warmerdam, Robert, Jankipersadsing, Soesma A., Vrooman, J. Cok, Reijneveld, Sijmen A., Brouwer, Sandra

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