The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury von McDaniel, Kelly, Huang, Li, Sato, Keisaku, Wu, Nan, Annable, Tami, Zhou, Tianhao, Ramos-Lorenzo, Sugeily, Wan, Ying, Huang, Qiaobing, Francis, Heather, Glaser, Shannon, Tsukamoto, Hidekazu, Alpini, Gianfranco, Meng, Fanyin

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Role of stem cells during diabetic liver injury von Wan, Ying, Garner, Jessica, Wu, Nan, Phillip, Levine, Han, Yuyan, McDaniel, Kelly, Annable, Tami, Zhou, Tianhao, Francis, Heather, Glaser, Shannon, Huang, Qiaobing, Alpini, Gianfranco, Meng, Fanyin

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Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules von Hari, Malathi, Loganzo, Frank, Annable, Tami, Tan, Xingzhi, Musto, Sylvia, Morilla, Daniel B, Nettles, James H, Snyder, James P, Greenberger, Lee M

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KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo von Hassig, Christian A, Symons, Kent T, Guo, Xin, Nguyen, Phan-Manh, Annable, Tami, Wash, Paul L, Payne, Joseph E, Jenkins, David A, Bonnefous, Céline, Trotter, Carol, Wang, Yan, Anzola, John V, Milkova, Elena L, Hoffman, Timothy Z, Dozier, Sara J, Wiley, Brandon M, Saven, Alan, Malecha, James W, Davis, Robert L, Muhammad, Jerry, Shiau, Andrew K, Noble, Stewart A, Rao, Tadimeti S, Smith, Nicholas D, Hager, Jeffrey H

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MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo von Sampath, Deepak, Discafani, Carolyn M, Loganzo, Frank, Beyer, Carl, Liu, Hao, Tan, Xingzhi, Musto, Sylvia, Annable, Tami, Gallagher, Patricia, Rios, Carol, Greenberger, Lee M

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Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury von Wan, Ying, McDaniel, Kelly, Wu, Nan, Ramos-Lorenzo, Sugeily, Glaser, Trenton, Venter, Julie, Francis, Heather, Kennedy, Lindsey, Sato, Keisaku, Zhou, Tianhao, Kyritsi, Konstantina, Huang, Qiaobing, Annable, Tami, Wu, Chaodong, Glaser, Shannon, Alpini, Gianfranco, Meng, Fanyin

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Identification of KD5170 : A novel mercaptoketone-based histone deacetylase inhibitor von PAYNE, Joseph E, BONNEFOUS, Céline, SHIAU, Andrew K, MALECHA, James W, NOBLE, Stewart A, HAGER, Jeffrey H, SMITH, Nicholas D, HASSIG, Christian A, SYMONS, Kent T, XIN GUO, NGUYEN, Phan-Manh, ANNABLE, Tami, WASH, Paul L, HOFFMAN, Timothy Z, RAO, Tadimeti S

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Knockout of microRNA-21 attenuates alcoholic hepatitis through the VHL/NF-κB signaling pathway in hepatic stellate cells von Wu, Nan, McDaniel, Kelly, Zhou, Tianhao, Ramos-Lorenzo, Sugeily, Wu, Chaodong, Huang, Li, Chen, Demeng, Annable, Tami, Francis, Heather, Glaser, Shannon, Alpini, Gianfranco, Meng, Fanyin

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Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in α-tubulin von Loganzo, Frank, Hari, Malathi, Annable, Tami, Tan, Xingzhi, Morilla, Daniel B, Musto, Sylvia, Zask, Arie, Kaplan, Joshua, Minnick, Jr, Albert A, May, Michael K, Ayral-Kaloustian, Semiramis, Poruchynsky, Marianne S, Fojo, Tito, Greenberger, Lee M

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A New Antiestrogen, 2-(4-Hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), Inhibits the Growth of Tamoxifen-sensitive and -resi... von GREENBERGER, Lee M, ANNABLE, Tami, COLLINS, Karen I, KOMM, Barry S, LYTTLE, C. Richard, MILLER, Chris P, SATYASWAROOP, Pondichery G, YIXIAN ZHANG, FROST, Philip

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236 miR-34a Regulates Cellular Senescence in Activated Hepatic Stellate Cells During Alcohol Induced Hepatic Injury von Wan, Ying, Han, Yuyan, McDaniel, Kelly, Annable, Tami, Wu, Nan, Venter, Julie, Francis, Heather L, Glaser, Shannon, Alpini, Gianfranco, Meng, Fanyin

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Sa1718 C-Myc-Regulated Biliary Cellular Senescence and Functional Heterogeneity During Cholestatic Liver Injury von Han, Yuyan, Wu, Nan, McDaniel, Kelly, Wan, Ying, Venter, Julie, Annable, Tami, Ray, Debolina, Avila, Shanika, Francis, Heather L, Glaser, Shannon, Meng, Fanyin, Alpini, Gianfranco

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Sa1715 Regulation of Cellular Senescence by the microRNA-34a/p53 Axis During Alcoholic Liver Injury von Annable, Tami, McDaniel, Kelly, Han, Yuyan, Venter, Julie, Wu, Nan, Glaser, Shannon, Wan, Ying, Francis, Heather L, Alpini, Gianfranco, Meng, Fanyin

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457 Impact of MT2 Melatonin Receptor Deletion on Cellular Senescence in Cholangiocytes Isolated From Mice After Cholestatic Liver Injury von Wu, Nan, Wan, Ying, Han, Yuyan, Annable, Tami, Ray, Debolina, Venter, Julie, Avila, Shanika, Standeford, Holly A, Francis, Heather L, Glaser, Shannon, Meng, Fanyin, Alpini, Gianfranco

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HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo von LOGANZO, Frank, DISCAFANI, Carolyn M, SINGANALLORE, Thiruvikraman, KHAFIZOVA, Gulnaz, PORUCHYNSKY, Marianne S, FOJO, Tito, NIEMAN, James A, AYRAL-KALOUSTIAN, Semiramis, ZASK, Arie, ANDERSEN, Raymond J, GREENBERGER, Lee M, ANNABLE, Tami, BEYER, Carl, MUSTO, Sylvia, HARI, Malathi, XINGZHI TAN, HARDY, Carolyn, HERNANDEZ, Richard, BAXTER, Michelle

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Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C von RABINDRAN, S. K, HAIYIN HE, SINGH, M, BROWN, E, COLLINS, K. I, ANNABLE, T, GREENBERGER, L. M

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2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as Covalent-Binding, Irreversible Inhibitors of the Kinase Domain of Vascular Endothelial Growth Factor Receptor-2 von Wissner, Allan, Floyd, M. Brawner, Johnson, Bernard D, Fraser, Heidi, Ingalls, Charles, Nittoli, Thomas, Dushin, Russell G, Discafani, Carolyn, Nilakantan, Ramaswamy, Marini, Joseph, Ravi, Malini, Cheung, Kinwang, Tan, Xingzhi, Musto, Sylvia, Annable, Tami, Siegel, Marshall M, Loganzo, Frank

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Tumor Cells Resistant to a Microtubule-Depolymerizing Hemiasterlin Analogue, HTI-286, Have Mutations in α- or β-Tubulin and Increased Microtubule Stability von Poruchynsky, Marianne S, Kim, Jong-Hyeok, Nogales, Eva, Annable, Tami, Loganzo, Frank, Greenberger, Lee M, Sackett, Dan L, Fojo, Tito

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Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment von YAMASHITA, Ayako, NORTON, Emily B, ZASK, Arie, AYRAL-KALOUSTIAN, Semiramis, KAPLAN, Joshua A, CHUAN NIU, LOGANZO, Frank, HERNANDEZ, Richard, BEYER, Carl F, ANNABLE, Tami, MUSTO, Sylvia, DISCAFANI, Carolyn

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α-Mercaptoketone based histone deacetylase inhibitors von Wash, Paul L., Hoffman, Timothy Z., Wiley, Brandon M., Bonnefous, Céline, Smith, Nicholas D., Sertic, Michael S., Lawrence, Charles M., Symons, Kent T., Nguyen, Phan-Manh, Lustig, Kevin D., Guo, Xin, Annable, Tami, Noble, Stewart A., Hager, Jeffrey H., Hassig, Christian A., Malecha, James W.

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