Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks von Suresh, Manasa, Korolowicz, Kyle E, Balarezo, Maria, Iyer, Radhakrishnan P, Padmanabhan, Seetharamaiyer, Cleary, Dillon, Gimi, Rayomand, Sheri, Anjaneyulu, Yon, Changsuek, Kallakury, Bhaskar V, Tucker, Robin D, Afdhal, Nezam, Menne, Stephan

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Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B von Korolowicz, Kyle E, Iyer, Radhakrishnan P, Czerwinski, Stefanie, Suresh, Manasa, Yang, Junming, Padmanabhan, Seetharamaiyer, Sheri, Anjaneyulu, Pandey, Rajendra K, Skell, Jeffrey, Marquis, Judith K, Kallakury, Bhaskar V, Tucker, Robin D, Menne, Stephan

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NOD2/RIG-I Activating Inarigivir Adjuvant Enhances the Efficacy of BCG Vaccine Against Tuberculosis in Mice von Khan, Arshad, Singh, Vipul K, Mishra, Abhishek, Soudani, Emily, Bakhru, Pearl, Singh, Christopher R, Zhang, Dekai, Canaday, David H, Sheri, Anjaneyulu, Padmanabhan, Seetharamaiyer, Challa, Sreerupa, Iyer, Radhakrishnan P, Jagannath, Chinnaswamy

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SB 9200, a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants von Jones, Meleri, Cunningham, Morven E., Wing, Peter, DeSilva, Sampath, Challa, Rupa, Sheri, Anjaneyulu, Padmanabhan, Seetharamaiyer, Iyer, Radhakrishnan P., Korba, Brent E., Afdhal, Nezam, Foster, Graham R.

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Penicillin Sulfone Inhibitors of Class D β-Lactamases von DRAWZ, Sarah M, BETHEL, Christopher R, BONOMO, Robert A, DOPPALAPUDI, Venkata R, SHERI, Anjaneyulu, SUNDAR RAM REDDY PAGADALA, HUJER, Andrea M, SKALWEIT, Marion J, ANDERSON, Vernon E, CHEN, Shu G, BUYNAK, John D

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Structures of SHV-1 β-lactamase with penem and penam sulfone inhibitors that form cyclic intermediates stabilized by carbonyl conjugation von Ke, Wei, Pattanaik, Priyaranjan, Bethel, Christopher R, Sheri, Anjaneyulu, Buynak, John D, Bonomo, Robert A, van den Akker, Focco

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Use of Raman Spectroscopy to Characterize Hydrogenation Reactions von Tumuluri, Venkat S, Kemper, Mark S, Sheri, Anjaneyulu, Choi, Seoung-Ryoung, Lewis, Ian R, Avery, Mitchell A, Avery, Bonnie A

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Preclinical studies of SB 11285, a novel STING agonist for immuno-oncology von Challa, Sreerupa Valli, Zhou, Shenghua, Sheri, Anjaneyulu, Padmanabhan, Seetharamaiyer, Meher, Geeta, Gimi, Rayomand, Schmidt, Diane, Cleary, Dillon, Afdhal, Nezam, Iyer, Radhakrishnan

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Novel small molecule nucleotide homologs (SMNH) activate human macrophages to kill intracellular Mycobacterium tuberculosis . (VAC6P.949) von Khan, Arshad, Singh, Christopher, Pandey, Rajendra, Sheri, Anjaneyulu, Padmanabhan, Seetharamaiyer, Iyer, Radhakrishan, Jagannath, Chinnaswamy

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Abstract B87: Mechanistic insights into the antitumor activity of SB 11285—a novel STING agonist von Zhou, Shenghua, Challa, Sreerupa, Nair, Vishal, Meher, Geeta, Sheri, Anjaneyulu, Gimi, Rayomand, Padmanabhan, Seetharamaiyer, Cleary, Dillon, Suppiah, Leena, Schmidt, Diane, Khedkar, Santosh, Iyer, Radhakrishnan

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Design, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 Carbapenemase von Bou, German, Santillana, Elena, Sheri, Anjaneyulu, Beceiro, Alejandro, Sampson, Jared M, Kalp, Matthew, Bethel, Christopher R, Distler, Anne M, Drawz, Sarah M, Pagadala, Sundar Ram Reddy, van den Akker, Focco, Bonomo, Robert A, Romero, Antonio, Buynak, John D

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Abstract B53: Development of SB 11 and SB 12, structurally unique linkage analogs of SB 11285 as STING agonists for Immuno-oncology von Zhou, Shenghua, Challa, Sreerupa, Shmidt, Diane, Suppiah, Leena, Nair, Vishal, Sheri, Anjaneyulu, Meher, Geeta, Gimi, Rayomand, Padmanabhan, Seetharamaiyer, Cleary, Dillon, Iyer, Radhakrishnan

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Abstract B75: Nanoparticle formulation of the STING agonist SB 11285 von Challa, Sreerupa, Suppiah, Leena, Cleary, Dillon, Sheri, Anjaneyulu, Gimi, Rayomand, Meher, Geeta, Padmanabhan, Seetharamaiyer, Shah, Sumit, Bhatt, Pranav, Tauro, Jovita, Iyer, Radhakrishnan

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Abstract B39: Novel dinucleotides that activate STING signaling for immuno-oncology von Zhou, Shenghua, Challa, Sreerupa, Padmanabhan, Seetharamaiyer, Sheri, Anjaneyulu, Delaney, Samantha, Meher, Geeta, Cleary, Dillon, Gimi, Rayomand, Khedkar, Santosh, Iyer, Radhakrishnan

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Design, Synthesis and Evaluation of Trisubstituted Thiazoles Targeting Plasmodium Falciparum Cysteine Proteases von Goud, P. Mallikarjun, Sheri, Anjaneyulu, Desai, Prashant V., Watkins, E. Blake, Tekwani, Babu, Sabnis, Yogesh, Gut, Jiri, Rosenthal, Philip J., Avery, Mitchell A.

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Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum von Weldon, David J, Shah, Falgun, Chittiboyina, Amar G, Sheri, Anjaneyulu, Chada, Raji Reddy, Gut, Jiri, Rosenthal, Philip J, Shivakumar, Develeena, Sherman, Woody, Desai, Prashant, Jung, Jae-Chul, Avery, Mitchell A

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Structures of SHV-1 [beta]-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation von Ke, Wei, Pattanaik, Priyaranjan, Bethel, Christopher R, Sheri, Anjaneyulu, Buynak, John D, Bonomo, Robert A, van den Akker, Focco

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Abstract B40: Nucleotide analogs as novel STING agonists for immuno-oncology von Challa, Sreerupa, Zhou, Shenghua, Sheri, Anjaneyulu, Padmanabhan, Seetharamaiyer, Delaney, Samantha, Meher, Geeta, Cleary, Dillon, Nair, Vishal, Gimi, Rayomand, Khedkar, Santosh, Iyer, Radhakrishnan

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Sulbactam Forms Only Minimal Amounts of Irreversible Acrylate-Enzyme with SHV-1 β-Lactamase von Totir, Monica A, Helfand, Marion S, Carey, Marianne P, Sheri, Anjaneyulu, Buynak, John D, Bonomo, Robert A, Carey, Paul R

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Rational Design of a β-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate:  1.28 Å Crystal Structure of wt SHV-1 Complex with a Penam Sulfone von Padayatti, Pius S, Sheri, Anjaneyulu, Totir, Monica A, Helfand, Marion S, Carey, Marianne P, Anderson, Vernon E, Carey, Paul R, Bethel, Christopher R, Bonomo, Robert A, Buynak, John D, van den Akker, Focco

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