TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury von Mazaheri, Fargol, Snaidero, Nicolas, Kleinberger, Gernot, Madore, Charlotte, Daria, Anna, Werner, Georg, Krasemann, Susanne, Capell, Anja, Trümbach, Dietrich, Wurst, Wolfgang, Brunner, Bettina, Bultmann, Sebastian, Tahirovic, Sabina, Kerschensteiner, Martin, Misgeld, Thomas, Butovsky, Oleg, Haass, Christian

Volltext

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import von Dormann, Dorothee, Rodde, Ramona, Edbauer, Dieter, Bentmann, Eva, Fischer, Ingeborg, Hruscha, Alexander, Than, Manuel E, Mackenzie, Ian R A, Capell, Anja, Schmid, Bettina, Neumann, Manuela, Haass, Christian

Volltext

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance von Xiang, Xianyuan, Werner, Georg, Bohrmann, Bernd, Liesz, Arthur, Mazaheri, Fargol, Capell, Anja, Feederle, Regina, Knuesel, Irene, Kleinberger, Gernot, Haass, Christian

Volltext

Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology von Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Schlepckow, Kai, Araque Caballero, Miguel Ángel, Franzmeier, Nicolai, Capell, Anja, Fellerer, Katrin, Nuscher, Brigitte, Eren, Erden, Levin, Johannes, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M, Cruchaga, Carlos, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael, Ewers, Michael, Haass, Christian

Volltext

Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice von Götzl, Julia K, Colombo, Alessio-Vittorio, Fellerer, Katrin, Reifschneider, Anika, Werner, Georg, Tahirovic, Sabina, Haass, Christian, Capell, Anja

Volltext

Long Noncoding RNAs-Related Diseases, Cancers, and Drugs von Chang, Hsueh-Wei, Liaw, Chih-Chuang, Huang, Hurng-Wern, Hou, Ming-Feng, Chang, Yung-Ting, Lee, Jin-Ching, Tang, Jen-Yang

Volltext

Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis von Götzl, Julia K., Mori, Kohji, Damme, Markus, Fellerer, Katrin, Tahirovic, Sabina, Kleinberger, Gernot, Janssens, Jonathan, van der Zee, Julie, Lang, Christina M., Kremmer, Elisabeth, Martin, Jean-Jacques, Engelborghs, Sebastiaan, Kretzschmar, Hans A., Arzberger, Thomas, Van Broeckhoven, Christine, Haass, Christian, Capell, Anja

Volltext

Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism von Götzl, Julia K, Brendel, Matthias, Werner, Georg, Parhizkar, Samira, Sebastian Monasor, Laura, Kleinberger, Gernot, Colombo, Alessio‐Vittorio, Deussing, Maximilian, Wagner, Matias, Winkelmann, Juliane, Diehl‐Schmid, Janine, Levin, Johannes, Fellerer, Katrin, Reifschneider, Anika, Bultmann, Sebastian, Bartenstein, Peter, Rominger, Axel, Tahirovic, Sabina, Smith, Scott T, Madore, Charlotte, Butovsky, Oleg, Capell, Anja, Haass, Christian

Volltext

Membrane Orientation and Subcellular Localization of Transmembrane Protein 106B (TMEM106B), a Major Risk Factor for Frontotemporal Lobar Degeneration von Lang, Christina M., Fellerer, Katrin, Schwenk, Benjamin M., Kuhn, Peer-Hendrik, Kremmer, Elisabeth, Edbauer, Dieter, Capell, Anja, Haass, Christian

Volltext

The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons von Lüningschrör, Patrick, Werner, Georg, Stroobants, Stijn, Kakuta, Soichiro, Dombert, Benjamin, Sinske, Daniela, Wanner, Renate, Lüllmann-Rauch, Renate, Wefers, Benedikt, Wurst, Wolfgang, D’Hooge, Rudi, Uchiyama, Yasuo, Sendtner, Michael, Haass, Christian, Saftig, Paul, Knöll, Bernd, Capell, Anja, Damme, Markus

Volltext

Mechanisms of Granulin Deficiency: Lessons from Cellular and Animal Models von Kleinberger, Gernot, Capell, Anja, Haass, Christian, Van Broeckhoven, Christine

Volltext

Physiological shedding and C-terminal proteolytic processing of TMEM106B von Held, Sebastian, Erck, Christian, Kemppainen, Susanna, Bleibaum, Florian, Giridhar, Neha Jadhav, Feederle, Regina, Krenner, Claudia, Juopperi, Sini-Pauliina, Calliari, Anna, Mentrup, Torben, Schröder, Bernd, Dickson, Dennis W., Rauramaa, Tuomas, Petrucelli, Leonard, Prudencio, Mercedes, Hiltunen, Mikko, Lüningschrör, Patrick, Capell, Anja, Damme, Markus

Volltext

Missense Mutations in the Progranulin Gene Linked to Frontotemporal Lobar Degeneration with Ubiquitin-immunoreactive Inclusions Reduce Progranulin Production and Secretion von Shankaran, Sunita S., Capell, Anja, Hruscha, Alexander T., Fellerer, Katrin, Neumann, Manuela, Schmid, Bettina, Haass, Christian

Volltext

Lack of a protective effect of the Tmem106b "protective SNP" in the Grn knockout mouse model for frontotemporal lobar degeneration von Cabron, Anne-Sophie, Borgmeyer, Uwe, Richter, Julia, Peisker, Helga, Gutbrod, Katharina, Dörmann, Peter, Capell, Anja, Damme, Markus

Volltext

Depletion and activation of microglia impact metabolic connectivity of the mouse brain von Gnörich, Johannes, Reifschneider, Anika, Wind, Karin, Zatcepin, Artem, Kunte, Sebastian T, Beumers, Philipp, Bartos, Laura M, Wiedemann, Thomas, Grosch, Maximilian, Xiang, Xianyuan, Fard, Maryam K, Ruch, Francois, Werner, Georg, Koehler, Mara, Slemann, Luna, Hummel, Selina, Briel, Nils, Blume, Tanja, Shi, Yuan, Biechele, Gloria, Beyer, Leonie, Eckenweber, Florian, Scheifele, Maximilian, Bartenstein, Peter, Albert, Nathalie L, Herms, Jochen, Tahirovic, Sabina, Haass, Christian, Capell, Anja, Ziegler, Sibylle, Brendel, Matthias

Volltext

Presenilin-1 Mutations of Leucine 166 Equally Affect the Generation of the Notch and APP Intracellular Domains Independent of Their Effect on Aβ42Production von Moehlmann, Tobias, Winkler, Edith, Xia, Xuefeng, Edbauer, Dieter, Murrell, Jill, Capell, Anja, Kaether, Christoph, Zheng, Hui, Ghetti, Bernardino, Haass, Christian, Steiner, Harald

Volltext

Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model von Rudan Njavro, Jasenka, Vukicevic, Marija, Fiorini, Emma, Dinkel, Lina, Müller, Stephan A, Berghofer, Anna, Bordier, Chiara, Kozlov, Stanislav, Halle, Annett, Buschmann, Katrin, Capell, Anja, Giudici, Camilla, Willem, Michael, Feederle, Regina, Lichtenthaler, Stefan F, Babolin, Chiara, Montanari, Paolo, Pfeifer, Andrea, Kosco-Vilbois, Marie, Tahirovic, Sabina

Volltext

Decreased Erythrocyte NA+,K+-ATPase Activity and Increased Plasma TBARS in Prehypertensive Patients von Malfatti, Carlos Ricardo Maneck, Burgos, Leandro Tibiriçá, Rieger, Alexandre, Rüdger, Cássio Luiz, Túrmina, Janaína Angela, Pereira, Ricardo Aparecido, Pavlak, João Lang, Silva, Luiz Augusto, Osiecki, Raul

Volltext

A Basolateral Sorting Signal Directs ADAM10 to Adherens Junctions and Is Required for Its Function in Cell Migration von Wild-Bode, Christine, Fellerer, Katrin, Kugler, Johanna, Haass, Christian, Capell, Anja

Volltext

Modelling the Effects of Ageing Time of Starch on the Enzymatic Activity of Three Amylolytic Enzymes von Guerra, Nelson Pérez, Pastrana Castro, Lorenzo

Volltext