Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer von Sayar, Erolcan, Patel, Radhika A, Coleman, Ilsa M, Roudier, Martine P, Zhang, Ailin, Mustafi, Pallabi, Low, Jin-Yih, Hanratty, Brian, Ang, Lisa S, Bhatia, Vipul, Adil, Mohamed, Bakbak, Hasim, Quigley, David A, Schweizer, Michael T, Hawley, Jessica E, Kollath, Lori, True, Lawrence D, Feng, Felix Y, Bander, Neil H, Corey, Eva, Lee, John K, Morrissey, Colm, Gulati, Roman, Nelson, Peter S, Haffner, Michael C

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Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer von De Sarkar, Navonil, Dasgupta, Sayan, Chatterjee, Payel, Coleman, Ilsa, Ha, Gavin, Ang, Lisa S., Kohlbrenner, Emily A., Frank, Sander B., Nunez, Talina A., Salipante, Stephen J., Corey, Eva, Morrissey, Colm, Van Allen, Eliezer, Schweizer, Michael T., Haffner, Michael C., Patel, Radhika, Hanratty, Brian, Lucas, Jared M., Dumpit, Ruth F., Pritchard, Colin C., Montgomery, Robert B., Nelson, Peter S.

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Apolipoprotein E, an important player in longevity and age-related diseases von Ang, Lisa S., Cruz, Rani P., Hendel, Alon, Granville, David J.

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Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth von Nyquist, Michael D., Ang, Lisa S., Corella, Alexandra, Coleman, Ilsa M., Meers, Michael P., Christiani, Anthony J., Pierce, Cordell, Janssens, Derek H., Meade, Hannah E., Bose, Arnab, Brady, Lauren, Howard, Timothy, De Sarkar, Navonil, Frank, Sander B., Dumpit, Ruth F., Dalton, James T., Corey, Eva, Plymate, Stephen R., Haffner, Michael C., Mostaghel, Elahe A., Nelson, Peter S.

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Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes von De Sarkar, Navonil, Patton, Robert D, Doebley, Anna-Lisa, Hanratty, Brian, Adil, Mohamed, Kreitzman, Adam J, Sarthy, Jay F, Ko, Minjeong, Brahma, Sandipan, Meers, Michael P, Janssens, Derek H, Ang, Lisa S, Coleman, Ilsa M, Bose, Arnab, Dumpit, Ruth F, Lucas, Jared M, Nunez, Talina A, Nguyen, Holly M, McClure, Heather M, Pritchard, Colin C, Schweizer, Michael T, Morrissey, Colm, Choudhury, Atish D, Baca, Sylvan C, Berchuck, Jacob E, Freedman, Matthew L, Ahmad, Kami, Haffner, Michael C, Montgomery, R Bruce, Corey, Eva, Henikoff, Steven, Nelson, Peter S, Ha, Gavin

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Granzyme B Deficiency Protects against Angiotensin II–Induced Cardiac Fibrosis von Shen, Yue, Cheng, Fang, Sharma, Mehul, Merkulova, Yulia, Raithatha, Sheetal A, Parkinson, Leigh G, Zhao, Hongyan, Westendorf, Kathryn, Bohunek, Lubos, Bozin, Tatjana, Hsu, Ivy, Ang, Lisa S, Williams, Sarah J, Bleackley, R. Chris, Eriksson, John E, Seidman, Michael A, McManus, Bruce M, Granville, David J

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The future of patient-derived xenografts in prostate cancer research von Lawrence, Mitchell G., Taylor, Renea A., Cuffe, Georgia B., Ang, Lisa S., Clark, Ashlee K., Goode, David L., Porter, Laura H., Le Magnen, Clémentine, Navone, Nora M., Schalken, Jack A., Wang, Yuzhuo, van Weerden, Wytske M., Corey, Eva, Isaacs, John T., Nelson, Peter S., Risbridger, Gail P.

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Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth (vol 131, e146777, 2021) von Nyquist, D. Michael, Mostaghel, A. Elahe, Nelson, S. Peter

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Perforin-Independent Extracellular Granzyme B Activity Contributes to Abdominal Aortic Aneurysm von Chamberlain, Ciara M, Ang, Lisa S, Boivin, Wendy A, Cooper, Dawn M, Williams, Sarah J, Zhao, Hongyan, Hendel, Alon, Folkesson, Maggie, Swedenborg, Jesper, Allard, Michael F, McManus, Bruce M, Granville, David J

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Comprehensive assessment of anaplastic lymphoma kinase in localized and metastatic prostate cancer reveals targetable alterations von Patel, Radhika A, Coleman, Ilsa, Roudier, Martine P, Konnick, Eric Q, Hanratty, Brian, Dumpit, Ruth, Lucas, Jared M, Ang, Lisa S, Low, Jin-Yih, Tretiakova, Maria S, Ha, Gavin, Lee, John K, True, Lawrence D, De Marzo, Angelo M, Nelson, Peter S, Morrissey, Colm, Pritchard, Colin C, Haffner, Michael C

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Abstract 11078: Granzyme B Deficiency Protects Against Angiotensin II-induced Cardiac Fibrosis via a Perforin-independent Mechanism von Shen, Yue, Cheng, Fang, Sharma, Mehul, Merkulova, Yulia, Raithatha, Sheetal A, Parkinson, Leigh G, Zhao, Hongyan, Westendorf, Kathryn, Bohunek, Lubos, Bozin, Tatjana, Hsu, Ivy, Ang, Lisa S, Williams, Sarah J, Bleackley, R C, Eriksson, John E, Seidman, Michael A, McManus, Bruce M, Granville, David J

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Abstract 5309: Perforin-Independent Granzyme B-Mediated Extracellular Matrix Protein Cleavage Contributes to Abdominal Aortic Aneurysm von Ang, Lisa S, Boivin, Wendy A, Williams, Sarah J, Chamberlain, Ciara M, Zhao, Hongyan, Allard, Michael F, McManus, Bruce M, Granville, David J

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Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations von Loh, Kyle M., Ang, Lay Teng, Zhang, Jingyao, Kumar, Vibhor, Ang, Jasmin, Auyeong, Jun Qiang, Lee, Kian Leong, Choo, Siew Hua, Lim, Christina Y.Y., Nichane, Massimo, Tan, Junru, Noghabi, Monireh Soroush, Azzola, Lisa, Ng, Elizabeth S., Durruthy-Durruthy, Jens, Sebastiano, Vittorio, Poellinger, Lorenz, Elefanty, Andrew G., Stanley, Edouard G., Chen, Qingfeng, Prabhakar, Shyam, Weissman, Irving L., Lim, Bing

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Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study von Young, Barnaby E, Fong, Siew-Wai, Chan, Yi-Hao, Mak, Tze-Minn, Ang, Li Wei, Anderson, Danielle E, Lee, Cheryl Yi-Pin, Amrun, Siti Naqiah, Lee, Bernett, Goh, Yun Shan, Su, Yvonne C F, Wei, Wycliffe E, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Chen, Yuan Yi Constance, Barkham, Timothy, Lin, Raymond Tzer Pin, Maurer-Stroh, Sebastian, Leo, Yee-Sin, Wang, Lin-Fa, Renia, Laurent, Lee, Vernon J, Smith, Gavin J D, Lye, David Chien, Ng, Lisa F P

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Designing Photochromic Materials with Large Luminescence Modulation and Strong Photochromic Efficiency for Dual‐Mode Rewritable Optical Storage von Yang, Zetian, Du, Jiaren, Martin, Lisa I. D. J., Feng, Ang, Cosaert, Ewoud, Zhao, Bo, Liu, Wanlu, Van Deun, Rik, Vrielinck, Henk, Poelman, Dirk

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Accuracy of MR imaging-estimated proton density fat fraction for classification of dichotomized histologic steatosis grades in nonalcoholic fatty liver disease von Tang, An, Desai, Ajinkya, Hamilton, Gavin, Wolfson, Tanya, Gamst, Anthony, Lam, Jessica, Clark, Lisa, Hooker, Jonathan, Chavez, Tanya, Ang, Brandon D, Middleton, Michael S, Peterson, Michael, Loomba, Rohit, Sirlin, Claude B

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome von Carvajal-Vergara, Xonia, Lemischka, Ihor R, Sevilla, Ana, D'Souza, Sunita L, Ang, Yen-Sin, Schaniel, Christoph, Lee, Dung-Fang, Yang, Lei, Kaplan, Aaron D, Adler, Eric D, Rozov, Roye, Ge, YongChao, Cohen, Ninette, Edelmann, Lisa J, Chang, Betty, Waghray, Avinash, Su, Jie, Pardo, Sherly, Lichtenbelt, Klaske D, Tartaglia, Marco, Gelb, Bruce D

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Developing classification criteria for skin‐predominant dermatomyositis: the Delphi process von Concha, J.S.S., Pena, S., Gaffney, R. G., Patel, B., Tarazi, M., Kushner, C. J., Merola, J.F., Fiorentino, D., Dutz, J.P., Goodfield, M., Nyberg, F., Volc‐Platzer, B., Fujimoto, M., Ang, C.C., Werth, V.P., Abuav, Rachel, Aggarwal, Rohit, Avashia‐Khemka, Nidhi, Callen, Jeffrey P., Cardones, Adela Rambi G., Chisolm, Sarah S., Chong, Benjamin F., Chung, Lorinda, Clarke, Jennie T., Kari Connolly, M., Costner, Melissa, Curran, Megan, Dourmishev, Lyubomir, Drage, Lisa A., Femia, Alisa N., Fernandez, Anthony P., Fett, Nicole, Foulke, Galen, Franks, Andrew G., Haemel, Anna, Hamaguchi, Yasuhito, Hansen, Christopher B., Imadojemu, Sotonye, Jia Ker, Khor, Kim, Hee Joo, Kurtzman, Drew JB, Lam, Christina, Laumann, Anne E., Lin, Julie, Mailhot, Jeffery D., Meggitt, Simon J, Micheletti, Robert G., Motegi, Sei‐ichiro, Muro, Yoshinao, O'Brien, Elizabeth, Pappas‐Taffer, Lisa, Paravar, Taraneh, Parodi, Aurora, Pearson, David R., Pinard, Joanie, Ramachandran, Sarika, Rider, Lisa G., Rosenbach, Misha, Sontheimer, Richard D., Sticherling, Michael, Vera Kellet, Cristián Andrés, Vleugels, Ruth Ann, Wetter, David A., Yamaguchi, Yukie

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Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress von Nyquist, Michael D., Corella, Alexandra, Coleman, Ilsa, De Sarkar, Navonil, Kaipainen, Arja, Ha, Gavin, Gulati, Roman, Ang, Lisa, Chatterjee, Payel, Lucas, Jared, Pritchard, Colin, Risbridger, Gail, Isaacs, John, Montgomery, Bruce, Morrissey, Colm, Corey, Eva, Nelson, Peter S.

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Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study von Loomba, Rohit, Schork, Nicholas, Chen, Chi-Hua, Bettencourt, Ricki, Bhatt, Ana, Ang, Brandon, Nguyen, Phirum, Hernandez, Carolyn, Richards, Lisa, Salotti, Joanie, Lin, Steven, Seki, Ekihiro, Nelson, Karen E, Sirlin, Claude B, Brenner, David

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