Chronic Administration of the N -Methyl-D-Aspartate Receptor Antagonist Ketamine Improves Rett Syndrome Phenotype von Patrizi, Annarita, Picard, Nathalie, Simon, Alex Joseph, Gunner, Georgia, Centofante, Eleonora, Andrews, Nick Arthur, Fagiolini, Michela

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Four distinct trajectories of tau deposition identified in Alzheimer’s disease von Vogel, Jacob W., Young, Alexandra L., Oxtoby, Neil P., Smith, Ruben, Ossenkoppele, Rik, Strandberg, Olof T., La Joie, Renaud, Aksman, Leon M., Grothe, Michel J., Iturria-Medina, Yasser, Pontecorvo, Michael J., Devous, Michael D., Rabinovici, Gil D., Alexander, Daniel C., Lyoo, Chul Hyoung, Evans, Alan C., Hansson, Oskar

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Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label... von Bach, Simon P, Gilbert, Alexandra, Korsgen, Stephan, Geh, Ian, Hill, James, Gill, Talvinder, Tutton, Matthew G, Khan, Jim, Robinson, Jonathan, Steward, Mark, Cunningham, Christopher, Beveridge, Alan, Handley, Kelly, Vince, Alex, Hilken, Nick, Sidile, Chakanaka, Wilcockson, Adrian, Peto, Richard, Crosby, Tom, Olliff, Julie, Ashok, Katti, Slawik, Simone, Smethurst, Andrew, Sripadam, Rajaram, Tagore, Veena, Terlizzo, Monica, Nisar, Pasha, Stewart, Alexandra, Trickett, Jonathan, Ashish, Bansal, Billings, Peter, Chandran, Palanichamy, Corr, Conor, Favill, Edward, Gollins, Simon, Marsh, Peter, Rajagopal, Ramesh, Cooper, Rachel, Hatfield, Paul, Lowe, Andy, Ostrowski, Julian, Robinson, Jonathan, Simpson, Rhian, Adams, Richard, Bleehen, Robert, Morgan, Meleri, Boone, Darren, Lacey, Nicola, Stunell, Helen, Wu, Shaobin, Hadaki, Maher, Blunt, Dominic, Cleator, Susan, Darzi, Ara, Goldin, Robert, Dobson, Mike, Pitt, Mark, Susnerwala, Shabbir, Williamson, Deborah, Howarth, Georgina, Horgan, Alan, McDonald, Fiona, Scott, John, Simmons, Timothy, Biswas, Debashis, Hernon, James, Kapur, Sandeep, Sington, James, Speakman, Christopher, Williams, Stuart, Garg, Dharmendra, Gill, Talvinder, Hegab, Mohammed, Hobday, Catherine, Shrimankar, Jyotsna, Jones, Oliver, Mortensen, Neil, Slater, Andrew, Wang, Lai, Warren, Bryan, Weaver, Andrew, Flubacher, Maxine, Tarver, David, Beable, Richard, Cowlishaw, David, Vogiatzis, Prokopios, Saunders, Mark, Teo, Mark, Geh, Ian, Glaholm, John, Goldstein, Mark, Langman, Gerald, Morton, Dion, Falk, Stephen, Thomas, Michael, Haba, Yasser, Harris, Guy, Hookway, Max, Skull, Angela, Umar, Tijani

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Genomic analyses identify molecular subtypes of pancreatic cancer von Bailey, Peter, Chang, David K., Nones, Katia, Johns, Amber L., Patch, Ann-Marie, Gingras, Marie-Claude, Miller, David K., Christ, Angelika N., Bruxner, Tim J. C., Quinn, Michael C., Nourse, Craig, Murtaugh, L. Charles, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourbakhsh, Ehsan, Wani, Shivangi, Fink, Lynn, Holmes, Oliver, Chin, Venessa, Anderson, Matthew J., Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Waddell, Nick, Wood, Scott, Xu, Qinying, Wilson, Peter J., Cloonan, Nicole, Kassahn, Karin S., Taylor, Darrin, Quek, Kelly, Robertson, Alan, Pantano, Lorena, Mincarelli, Laura, Sanchez, Luis N., Evers, Lisa, Wu, Jianmin, Pinese, Mark, Cowley, Mark J., Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chantrill, Lorraine A., Mawson, Amanda, Humphris, Jeremy, Chou, Angela, Pajic, Marina, Scarlett, Christopher J., Pinho, Andreia V., Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S., Kench, James G., Lovell, Jessica A., Merrett, Neil D., Toon, Christopher W., Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Moran-Jones, Kim, Jamieson, Nigel B., Graham, Janet S., Duthie, Fraser, Oien, Karin, Hair, Jane, Grützmann, Robert, Maitra, Anirban, Iacobuzio-Donahue, Christine A., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Corbo, Vincenzo, Bassi, Claudio, Rusev, Borislav, Capelli, Paola, Salvia, Roberto, Tortora, Giampaolo, Mukhopadhyay, Debabrata, Petersen, Gloria M., Munzy, Donna M., Fisher, William E., Karim, Saadia A., Eshleman, James R., Hruban, Ralph H., Pilarsky, Christian, Sansom, Owen J., Scarpa, Aldo, Bailey, Ulla-Maja Hagbo, Hofmann, Oliver, Sutherland, Robert L., Wheeler, David A., Gill, Anthony J., Gibbs, Richard A., Pearson, John V., Waddell, Nicola, Biankin, Andrew V., Grimmond, Sean M.

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Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease von Vogel, Jacob W., Iturria-Medina, Yasser, Strandberg, Olof T., Smith, Ruben, Levitis, Elizabeth, Evans, Alan C., Hansson, Oskar

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Whole genomes redefine the mutational landscape of pancreatic cancer von Waddell, Nicola, Pajic, Marina, Patch, Ann-Marie, Chang, David K., Kassahn, Karin S., Bailey, Peter, Johns, Amber L., Miller, David, Nones, Katia, Quek, Kelly, Quinn, Michael C. J., Robertson, Alan J., Fadlullah, Muhammad Z. H., Bruxner, Tim J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Wilson, Peter J., Markham, Emma, Cloonan, Nicole, Anderson, Matthew J., Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen H., Leonard, Conrad, Newell, Felicity, Poudel, Barsha, Song, Sarah, Taylor, Darrin, Waddell, Nick, Wood, Scott, Xu, Qinying, Wu, Jianmin, Pinese, Mark, Cowley, Mark J., Lee, Hong C., Jones, Marc D., Nagrial, Adnan M., Humphris, Jeremy, Chantrill, Lorraine A., Chin, Venessa, Steinmann, Angela M., Mawson, Amanda, Humphrey, Emily S., Colvin, Emily K., Chou, Angela, Scarlett, Christopher J., Pinho, Andreia V., Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S., Kench, James G., Pettitt, Jessica A., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Jamieson, Nigel B., Graham, Janet S., Niclou, Simone P., Bjerkvig, Rolf, Grützmann, Robert, Aust, Daniela, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Corbo, Vincenzo, Bassi, Claudio, Falconi, Massimo, Zamboni, Giuseppe, Tortora, Giampaolo, Tempero, Margaret A., Gill, Anthony J., Eshleman, James R., Pilarsky, Christian, Scarpa, Aldo, Musgrove, Elizabeth A., Pearson, John V., Biankin, Andrew V., Grimmond, Sean M.

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Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis von Iturria-Medina, Y., Sotero, R. C., Toussaint, P. J., Mateos-Pérez, J. M., Evans, A. C.

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Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease von Moscoso, Alexis, Grothe, Michel J, Ashton, Nicholas J, Karikari, Thomas K, Lantero Rodríguez, Juan, Snellman, Anniina, Suárez-Calvet, Marc, Blennow, Kaj, Zetterberg, Henrik, Schöll, Michael

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Predicting Alzheimer’s disease progression using multi-modal deep learning approach von Lee, Garam, Nho, Kwangsik, Kang, Byungkon, Sohn, Kyung-Ah, Kim, Dokyoon

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In vivo staging of regional amyloid deposition von Grothe, Michel J, Barthel, Henryk, Sepulcre, Jorge, Dyrba, Martin, Sabri, Osama, Teipel, Stefan J

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Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease von Franzmeier, Nicolai, Neitzel, Julia, Rubinski, Anna, Smith, Ruben, Strandberg, Olof, Ossenkoppele, Rik, Hansson, Oskar, Ewers, Michael

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Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus von Silbergleit, Robert, Durkalski, Valerie, Lowenstein, Daniel, Conwit, Robin, Pancioli, Arthur, Palesch, Yuko, Barsan, William

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A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure von Yang, Zhijian, Nasrallah, Ilya M., Shou, Haochang, Wen, Junhao, Doshi, Jimit, Habes, Mohamad, Erus, Guray, Abdulkadir, Ahmed, Resnick, Susan M., Albert, Marilyn S., Maruff, Paul, Fripp, Jurgen, Morris, John C., Wolk, David A., Davatzikos, Christos

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Common genetic variants influence human subcortical brain structures von Hibar, Derrek P., Desrivières, Sylvane, Toro, Roberto, Wittfeld, Katharina, Abramovic, Lucija, Bernard, Manon, Chen, Qiang, Giddaluru, Sudheer, Janowitz, Deborah, Lee, Phil H., Ramasamy, Adaikalavan, Risacher, Shannon L., Rose, Emma J., Salami, Alireza, Schmaal, Lianne, Schork, Andrew J., Strike, Lachlan T., Walters, Raymond K., Winkler, Anderson M., Zwiers, Marcel P., Athanasiu, Lavinia, Hakobjan, Marina M. H., Hartberg, Cecilie B., Heister, Angelien J. G. A. M., Hoehn, David, Kasperaviciute, Dalia, Makkinje, Remco R. R., Reese McKay, D., Shen, Li, Walton, Esther, Ames, David, Corvin, Aiden, Curran, Joanne E., Dillman, Allissa, Erk, Susanne, Foroud, Tatiana M., Guelfi, Sebastian, Hegenscheid, Katrin, Hernandez, Dena G., Heslenfeld, Dirk J., Hottenga, Jouke-Jan, Jenkinson, Mark, Kanai, Ryota, Kent, Jack W., McMahon, Katie L., Meisenzahl, Eva, Mohnke, Sebastian, Mühleisen, Thomas W., Nalls, Michael A., Nichols, Thomas E., Potkin, Steven G., Reppermund, Simone, Rujescu, Dan, Schnell, Knut, Thalamuthu, Anbupalam, Turner, Jessica A., van 't Ent, Dennis, Wassink, Thomas H., Westman, Eric, Ashbrook, David G., Lu, Lu, Williams, Robert W., Buckner, Randy L., Calhoun, Vince D., Cavalleri, Gianpiero L., Dale, Anders M., Espeseth, Thomas, Hoffmann, Wolfgang, Le Hellard, Stephanie, Meyer-Lindenberg, Andreas, Müller-Myhsok, Bertram, Nyberg, Lars, Penninx, Brenda W. J. H., van Bokhoven, Hans, van Haren, Neeltje E. M., Völzke, Henry, Weiner, Michael W., White, Tonya, Agartz, Ingrid, Blangero, John, Boomsma, Dorret I., Fernández, Guillén, Fisher, Simon E., Francks, Clyde, Grabe, Hans J., Hashimoto, Ryota, Hulshoff Pol, Hilleke E., Jönsson, Erik G., McIntosh, Andrew M., Singleton, Andrew, Schmidt, Reinhold, Satizabal, Claudia L., Ebling, Maritza, Nyquist, Paul, Vinke, Louis N., Xue, Luting, Mazoyer, Bernard, Martin, Nicholas G., Wright, Margaret J., Schumann, Gunter

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Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease von Shirzadi, Zahra, Schultz, Stephanie A, Yau, Wai-Ying W, Joseph-Mathurin, Nelly, Fitzpatrick, Colleen D, Levin, Raina, Kantarci, Kejal, Preboske, Gregory M, Jack, Jr, Clifford R, Farlow, Martin R, Hassenstab, Jason, Jucker, Mathias, Morris, John C, Xiong, Chengjie, Karch, Celeste M, Levey, Allan I, Gordon, Brian A, Schofield, Peter R, Salloway, Stephen P, Perrin, Richard J, McDade, Eric, Levin, Johannes, Cruchaga, Carlos, Allegri, Ricardo F, Fox, Nick C, Goate, Alison, Day, Gregory S, Koeppe, Robert, Chui, Helena C, Berman, Sarah, Mori, Hiroshi, Sanchez-Valle, Raquel, Lee, Jae-Hong, Rosa-Neto, Pedro, Ruthirakuhan, Myuri, Wu, Che-Yuan, Swardfager, Walter, Benzinger, Tammie L S, Sohrabi, Hamid R, Martins, Ralph N, Bateman, Randall J, Johnson, Keith A, Sperling, Reisa A, Greenberg, Steven M, Schultz, Aaron P, Chhatwal, Jasmeer P

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Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis von Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Zhao, Qianhua, Chen, Keliang, Chen, Yuewen, Hardy, John, Li, Yun, Fu, Amy K. Y., Guo, Qihao, Ip, Nancy Y.

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Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology von Shen, Xinpeng, Ma, Sisi, Vemuri, Prashanthi, Simon, Gyorgy

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Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology von Schmitz, Taylor W., Nathan Spreng, R.

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Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease von Pichet Binette, Alexa, Franzmeier, Nicolai, Spotorno, Nicola, Ewers, Michael, Brendel, Matthias, Biel, Davina, Strandberg, Olof, Janelidze, Shorena, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Smith, Ruben, Stomrud, Erik, Ossenkoppele, Rik, Hansson, Oskar

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Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE von Ayton, Scott, Faux, Noel G., Bush, Ashley I.

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