Impact of tumour microenvironment and Fc receptors on the activity of immunomodulatory antibodies von Furness, Andrew J.S, Vargas, Frederick Arce, Peggs, Karl S, Quezada, Sergio A

Volltext

The spectrum of cardiovascular complications related to immune-checkpoint inhibitor treatment von Maria Sol Andres, Ramalingam, Sivatharshini, Rosen, Stuart D, Baksi, John, Khattar, Rajdeep, Kirichenko, Yulia, Young, Kate, Yousaf, Nadia, Okines, Alicia, Huddart, Robert, Harrington, Kevin, Andrew J.S. Furness, Samra Turajlic, Pickering, Lisa, Popat, Sanjay, Larkin, James

Volltext

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition von Litchfield, Kevin, Reading, James L., Puttick, Clare, Thakkar, Krupa, Abbosh, Chris, Bentham, Robert, Watkins, Thomas B.K., Rosenthal, Rachel, Biswas, Dhruva, Rowan, Andrew, Lim, Emilia, Al Bakir, Maise, Turati, Virginia, Guerra-Assunção, José Afonso, Conde, Lucia, Furness, Andrew J.S., Saini, Sunil Kumar, Hadrup, Sine R., Herrero, Javier, Lee, Se-Hoon, Van Loo, Peter, Enver, Tariq, Larkin, James, Hellmann, Matthew D., Turajlic, Samra, Quezada, Sergio A., McGranahan, Nicholas, Swanton, Charles

Volltext

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes von Bentzen, Amalie Kai, Marquard, Andrea Marion, Lyngaa, Rikke, Saini, Sunil Kumar, Ramskov, Sofie, Donia, Marco, Such, Lina, Furness, Andrew J S, McGranahan, Nicholas, Rosenthal, Rachel, Straten, Per thor, Szallasi, Zoltan, Svane, Inge Marie, Swanton, Charles, Quezada, Sergio A, Jakobsen, Søren Nyboe, Eklund, Aron Charles, Hadrup, Sine Reker

Volltext

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade von McGranahan, Nicholas, Furness, Andrew J. S., Rosenthal, Rachel, Ramskov, Sofie, Lyngaa, Rikke, Saini, Sunil Kumar, Jamal-Hanjani, Mariam, Wilson, Gareth A., Birkbak, Nicolai J., Hiley, Crispin T., Watkins, Thomas B. K., Shafi, Seema, Murugaesu, Nirupa, Mitter, Richard, Akarca, Ayse U., Linares, Joseph, Marafioti, Teresa, Henry, Jake Y., Van Allen, Eliezer M., Miao, Diana, Schilling, Bastian, Schadendorf, Dirk, Garraway, Levi A., Makarov, Vladimir, Rizvi, Naiyer A., Snyder, Alexandra, Hellmann, Matthew D., Merghoub, Taha, Wolchok, Jedd D., Shukla, Sachet A., Wu, Catherine J., Peggs, Karl S., Chan, Timothy A., Hadrup, Sine R., Quezada, Sergio A., Swanton, Charles

Volltext

Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2 von Au, Lewis, Fendler, Annika, Shepherd, Scott T. C., Rzeniewicz, Karolina, Cerrone, Maddalena, Byrne, Fiona, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Shon, John, Haynes, Winston A., Ward, Barry, Shum, Ben, Gordon, William, Gerard, Camille L., Xie, Wenyi, Joharatnam-Hogan, Nalinie, Young, Kate, Pickering, Lisa, Furness, Andrew J. S., Larkin, James, Harvey, Ruth, Kassiotis, George, Gandhi, Sonia, Swanton, Charles, Fribbens, Charlotte, Wilkinson, Katalin A., Wilkinson, Robert J., Lau, David K., Banerjee, Susana, Starling, Naureen, Chau, Ian, Turajlic, Samra

Volltext

Anti-programmed cell death-1 therapy and insulin-dependent diabetes: a case report von Martin-Liberal, Juan, Furness, Andrew JS, Joshi, Kroopa, Peggs, Karl S., Quezada, Sergio A., Larkin, James

Volltext

Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer von Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wu, Mary, Harvey, Ruth, Schmitt, Andreas M, Tippu, Zayd, Shum, Benjamin, Farag, Sheima, Rogiers, Aljosja, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C, Carr, Edward J, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Shea, Robyn L, Gardner, Gail, Murray, Darren, Yousaf, Nadia, Jhanji, Shaman, Tatham, Kate, Cunningham, David, Van As, Nicholas, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L V, Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Larkin, James, Turajlic, Samra

Volltext

Ipilimumab plus nivolumab in patients with symptomatic melanoma brain metastasis requiring corticosteroids von Manacorda, Simona, Carmena, Maria De Toro, Malone, Ciara, Linh Le, Ha Mo, Furness, Andrew J.S., Larkin, James, Schmitt, Andreas M.

Volltext

Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma von Kelderman, Sander, Heemskerk, Bianca, van Tinteren, Harm, van den Brom, Rob R. H., Hospers, Geke A. P., van den Eertwegh, Alfonsus J. M., Kapiteijn, Ellen W., de Groot, Jan Willem B., Soetekouw, Patricia, Jansen, Rob L., Fiets, Edward, Furness, Andrew J. S., Renn, Alexandra, Krzystanek, Marcin, Szallasi, Zoltan, Lorigan, Paul, Gore, Martin E., Schumacher, Ton N. M., Haanen, John B. A. G., Larkin, James M. G., Blank, Christian U.

Volltext

Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, in patients with advanced melanoma after progression on immune checkpoint... von Chesney, Jason, Lewis, Karl D, Kluger, Harriet, Hamid, Omid, Whitman, Eric, Thomas, Sajeve, Wermke, Martin, Cusnir, Mike, Domingo-Musibay, Evidio, Phan, Giao Q, Kirkwood, John M, Hassel, Jessica C, Orloff, Marlana, Larkin, James, Weber, Jeffrey, Furness, Andrew J S, Khushalani, Nikhil I, Medina, Theresa, Egger, Michael E, Graf Finckenstein, Friedrich, Jagasia, Madan, Hari, Parameswaran, Sulur, Giri, Shi, Wen, Wu, Xiao, Sarnaik, Amod

Volltext

Marrow-Infiltrating Regulatory T Cells Correlate with the Presence of Dysfunctional CD4 + PD-1 + Cells and Inferior Survival in Patients with Newly Diagnosed Multiple Myeloma von Alrasheed, Nouf, Lee, Lydia, Ghorani, Ehsan, Henry, Jake Y, Conde, Lucia, Chin, Melody, Galas-Filipowicz, Daria, Furness, Andrew J S, Chavda, Selina J, Richards, Huw, De-Silva, Dunnya, Cohen, Oliver C, Patel, Dominic, Brooks, Anthony, Rodriguez-Justo, Manuel, Pule, Martin, Herrero, Javier, Quezada, Sergio A, Yong, Kwee L

Volltext

Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer von Fendler, Annika, Shepherd, Scott T.C., Au, Lewis, Wilkinson, Katalin A., Wu, Mary, Schmitt, Andreas M., Tippu, Zayd, Farag, Sheima, Rogiers, Aljosja, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Shum, Benjamin, Gerard, Camille L., Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C., Carr, Edward J., Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Shea, Robyn L., Gardner, Gail, Murray, Darren, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Wilkinson, Robert J., Larkin, James, Turajlic, Samra

Volltext

Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas von Gerlinger, Marco, Quezada, Sergio A, Peggs, Karl S, Furness, Andrew JS, Fisher, Rosalie, Marafioti, Teresa, Shende, Vishvesh H, McGranahan, Nicholas, Rowan, Andrew J, Hazell, Steven, Hamm, David, Robins, Harlan S, Pickering, Lisa, Gore, Martin, Nicol, David L, Larkin, James, Swanton, Charles

Volltext

Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment von Wong, Yien Ning Sophia, Joshi, Kroopa, Khetrapal, Pramit, Ismail, Mazlina, Reading, James L, Sunderland, Mariana Werner, Georgiou, Andrew, Furness, Andrew J S, Ben Aissa, Assma, Ghorani, Ehsan, Oakes, Theres, Uddin, Imran, Tan, Wei Shen, Feber, Andrew, McGovern, Ursula, Swanton, Charles, Freeman, Alex, Marafioti, Teresa, Briggs, Timothy P, Kelly, John D, Powles, Thomas, Peggs, Karl S, Chain, Benjamin M, Linch, Mark D, Quezada, Sergio A

Volltext

The side effect registry immuno-oncology (SERIO) – A tool for systematic analysis of immunotherapy-induced side effects von Ertl, Carolin, Ruf, Theresa, Mentzer, Dirk, Kong, Mingzi, Kramer, Rafaela, Bergwelt-Baildon, Michael von, Subklewe, Marion, Tomsitz, Dirk, Ascierto, Paolo A., Dummer, Reinhard, Gogas, Helen, Lebbé, Celeste, Long, Georgina V., McArthur, Grant, Neilan, Tomas G., Ribas, Antoni, Robert, Caroline, Schadendorf, Dirk, Zimmer, Lisa, Eigentler, Thomas, Grabbe, Stephan, Forschner, Andrea, Kähler, Katharina C., Milani, Valeria, Pföhler, Claudia, Hassel, Jessica, Gutzmer, Ralf, Loquai, Carmen, Routy, Bertrand, Furness, Andrew J.S., Blank, Christian, Wolchok, Jedd D., French, Lars E., Hauschild, Axel, Heinzerling, Lucie

Volltext

Lifileucel: the first cellular therapy approved for solid tumours von Julve, Max, Lythgoe, Mark P, Larkin, James, Furness, Andrew J S

Volltext

Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer von Fendler, Annika, Shepherd, Scott T.C., Au, Lewis, Wilkinson, Katalin A., Wu, Mary, Schmitt, Andreas M., Tippu, Zayd, Farag, Sheima, Rogiers, Aljosja, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Shum, Benjamin, Gerard, Camille L., Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C., Carr, Edward J., Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Shea, Robyn L., Gardner, Gail, Murray, Darren, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Wilkinson, Robert J., Larkin, James, Turajlic, Samra

Volltext

Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer von Wu, Mary Y., Shepherd, Scott T.C., Fendler, Annika, Carr, Edward J., Au, Lewis, Harvey, Ruth, Dowgier, Giulia, Hobbs, Agnieszka, Herman, Lou S., Ragno, Martina, Adams, Lorin, Schmitt, Andreas M., Tippu, Zayd, Shum, Benjamin, Farag, Sheima, Rogiers, Aljosja, O’Reilly, Nicola, Bawumia, Philip, Smith, Callie, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Hepworth, Stephanie, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Deng, Daqi, Williams, Bryan, Brown, Michael, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Tatham, Kate, Cunningham, David, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Walker, Susanna, Nicholson, Emma, Larkin, James, Wall, Emma C., Turajlic, Samra

Volltext

From presentation to paper: Gender disparities in oncological research von Dijksterhuis, Willemieke P.M., Stroes, Charlotte I., Tan, Wan‐Ling, Ithimakin, Suthinee, Calles, Antonio, Oijen, Martijn G.H., Verhoeven, Rob H.A., Barriuso, Jorge, Oosting, Sjoukje F., Ivankovic, Daniela Kolarevic, Furness, Andrew J.S., Bozovic‐Spasojevic, Ivana, Gomez‐Roca, Carlos, Laarhoven, Hanneke W.M.

Volltext