The Pharmacology and Function of Receptors for Short-Chain Fatty Acids von Bolognini, Daniele, Tobin, Andrew B., Milligan, Graeme, Moss, Catherine E.

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Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival von Mok, Sachel, Stokes, Barbara H., Gnädig, Nina F., Ross, Leila S., Yeo, Tomas, Amaratunga, Chanaki, Allman, Erik, Solyakov, Lev, Bottrill, Andrew R., Tripathi, Jaishree, Fairhurst, Rick M., Llinás, Manuel, Bozdech, Zbynek, Tobin, Andrew B., Fidock, David A.

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The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Ther... von Hudson, Brian D., Shimpukade, Bharat, Mackenzie, Amanda E., Butcher, Adrian J., Pediani, John D., Christiansen, Elisabeth, Heathcote, Helen, Tobin, Andrew B., Ulven, Trond, Milligan, Graeme

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Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits von Nguyen, Huong T. M., Westhuizen, Emma T., Langmead, Christopher J., Tobin, Andrew B., Sexton, Patrick M., Christopoulos, Arthur, Valant, Celine

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How Arrestins and GRKs Regulate the Function of Long Chain Fatty Acid Receptors von Alharbi, Abdulrahman G, Tobin, Andrew B, Milligan, Graeme

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Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code von Butcher, Adrian J., Prihandoko, Rudi, Kong, Kok Choi, McWilliams, Phillip, Edwards, Jennifer M., Bottrill, Andrew, Mistry, Sharad, Tobin, Andrew B.

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Design of Next-Generation G Protein-Coupled Receptor Drugs: Linking Novel Pharmacology and In Vivo Animal Models von Bradley, Sophie J, Tobin, Andrew B

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Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease von Dwomoh, Louis, Tejeda, Gonzalo S, Tobin, Andrew B

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A golden age of muscarinic acetylcholine receptor modulation in neurological diseases von Tobin, Andrew B.

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A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias von Bolognini, Daniele, Moss, Catherine E., Nilsson, Karolina, Petersson, Annika U., Donnelly, Iona, Sergeev, Eugenia, König, Gabriele M., Kostenis, Evi, Kurowska-Stolarska, Mariola, Miller, Ashley, Dekker, Niek, Tobin, Andrew B., Milligan, Graeme

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Identification of Orthosteric and Allosteric Site Mutations in M2 Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias von Gregory, Karen J., Hall, Nathan E., Tobin, Andrew B., Sexton, Patrick M., Christopoulos, Arthur

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The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions von Fasciani, Irene, Petragnano, Francesco, Wang, Ziming, Edwards, Ruairidh, Telugu, Narasimha, Pietrantoni, Ilaria, Zabel, Ulrike, Zauber, Henrik, Grieben, Marlies, Terzenidou, Maria E, Di Gregorio, Jacopo, Pellegrini, Cristina, Santini, Jr, Silvano, Taddei, Anna R, Pohl, Bärbel, Aringhieri, Stefano, Carli, Marco, Aloisi, Gabriella, Marampon, Francesco, Charlesworth, Eve, Roman, Alexandra, Diecke, Sebastian, Flati, Vincenzo, Giorgi, Franco, Amicarelli, Fernanda, Tobin, Andrew B, Scarselli, Marco, Tokatlidis, Kostas, Rossi, Mario, Lohse, Martin J, Annibale, Paolo, Maggio, Roberto

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Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein–Coupled Receptor 120 von Prihandoko, Rudi, Alvarez-Curto, Elisa, Hudson, Brian D., Butcher, Adrian J., Ulven, Trond, Miller, Ashley M., Tobin, Andrew B., Milligan, Graeme

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Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and Bias von van der Westhuizen, Emma T, Choy, K H Christopher, Valant, Celine, McKenzie-Nickson, Simon, Bradley, Sophie J, Tobin, Andrew B, Sexton, Patrick M, Christopoulos, Arthur

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Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR von Burger, Wessel A. C., Pham, Vi, Vuckovic, Ziva, Powers, Alexander S., Mobbs, Jesse I., Laloudakis, Yianni, Glukhova, Alisa, Wootten, Denise, Tobin, Andrew B., Sexton, Patrick M., Paul, Steven M., Felder, Christian C., Danev, Radostin, Dror, Ron O., Christopoulos, Arthur, Valant, Celine, Thal, David M.

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A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia von Dean, Brian, Bakker, Geor, Ueda, Hiroki R, Tobin, Andrew B, Brown, Alastair, Kanaan, Richard A A

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M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss von Bradley, Sophie J, Bourgognon, Julie-Myrtille, Sanger, Helen E, Verity, Nicholas, Mogg, Adrian J, White, David J, Butcher, Adrian J, Moreno, Julie A, Molloy, Colin, Macedo-Hatch, Timothy, Edwards, Jennifer M, Wess, Jurgen, Pawlak, Robert, Read, David J, Sexton, Patrick M, Broad, Lisa M, Steinert, Joern R, Mallucci, Giovanna R, Christopoulos, Arthur, Felder, Christian C, Tobin, Andrew B

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction von Mahindra, Amit, Tejeda, Gonzalo, Rossi, Mario, Janha, Omar, Herbert, Imogen, Morris, Caroline, Morgan, Danielle C, Beattie, Wendy, Montezano, Augusto C, Hudson, Brian, Tobin, Andrew B, Bhella, David, Touyz, Rhian M, Jamieson, Andrew G, Baillie, George S, Blair, Connor M

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Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission von Kern, Selina, Agarwal, Shruti, Huber, Kilian, Gehring, André P, Strödke, Benjamin, Wirth, Christine C, Brügl, Thomas, Abodo, Liliane Onambele, Dandekar, Thomas, Doerig, Christian, Fischer, Rainer, Tobin, Andrew B, Alam, Mahmood M, Bracher, Franz, Pradel, Gabriele

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Chemogenetics defines a short-chain fatty acid receptor gut-brain axis von Barki, Natasja, Bolognini, Daniele, Börjesson, Ulf, Jenkins, Laura, Riddell, John, Hughes, David I, Ulven, Trond, Hudson, Brian D, Ulven, Elisabeth Rexen, Dekker, Niek, Tobin, Andrew B, Milligan, Graeme

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