A kinase-cGAS cascade to synthesize a therapeutic STING activator von McIntosh, John A., Liu, Zhijian, Andresen, Brian M., Marzijarani, Nastaran Salehi, Moore, Jeffrey C., Marshall, Nicholas M., Borra-Garske, Margie, Obligacion, Jennifer V., Fier, Patrick S., Peng, Feng, Forstater, Jacob H., Winston, Matthew S., An, Chihui, Chang, Wonsuk, Lim, Jongwon, Huffman, Mark A., Miller, Steven P., Tsay, Fuh-Rong, Altman, Michael D., Lesburg, Charles A., Steinhuebel, Dietrich, Trotter, B. Wesley, Cumming, Jared N., Northrup, Alan, Bu, Xiaodong, Mann, Benjamin F., Biba, Mirlinda, Hiraga, Kaori, Murphy, Grant S., Kolev, Joshua N., Makarewicz, Amanda, Pan, Weilan, Farasat, Iman, Bade, Rachel S., Stone, Kevin, Duan, Da, Alvizo, Oscar, Adpressa, Donovan, Guetschow, Erik, Hoyt, Erik, Regalado, Erik L., Castro, Steve, Rivera, Nelo, Smith, Joseph P., Wang, Fengqiang, Crespo, Alejandro, Verma, Deeptak, Axnanda, Stephanus, Dance, Zachary E. X., Devine, Paul N., Tschaen, David, Canada, Keith A., Bulger, Paul G., Sherry, Benjamin D., Truppo, Matthew D., Ruck, Rebecca T., Campeau, Louis-Charles, Bennett, David Jonathan, Humphrey, Guy R., Campos, Kevin R., Maddess, Matthew L.

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Palladium and Raney Nickel Catalyzed Methanolic Cleavage of Stable Borane−Amine Complexes von Couturier, Michel, Tucker, John L, Andresen, Brian M, Dubé, Pascal, Negri, Joanna T

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De Novo Synthesis of Modified Saxitoxins for Sodium Ion Channel Study von Andresen, Brian M, Du Bois, J

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Fluorescent Saxitoxins for Live Cell Imaging of Single Voltage-Gated Sodium Ion Channels beyond the Optical Diffraction Limit von Ondrus, Alison E., Lee, Hsiao-lu D., Iwanaga, Shigeki, Parsons, William H., Andresen, Brian M., Moerner, W.E., Du Bois, J.

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Phosphine-Mediated [4 + 2] Annulation of Bis(enones):  A Lewis Base Catalyzed “Mock Diels−Alder” Reaction von Couturier, Michel, Ménard, Fréderic, Ragan, John A, Riou, Maxime, Dauphin, Etienne, Andresen, Brian M, Ghosh, Arun, Dupont-Gaudet, Kristina, Girardin, Mélina

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Streamlined Processes for the Synthesis of a Farnesyl Transferase Inhibitor Drug Candidate von Andresen, Brian M., Couturier, Michel, Cronin, Brian, D'Occhio, Michael, Ewing, Marcus D., Guinn, Mark, Hawkins, Joel M., Jasys, V. John, LaGreca, Susan D., Lyssikatos, Joseph P., Moraski, Garrett, Ng, Karl, Raggon, Jeffrey W., Stewart, A. Morgan, Tickner, Derek L., Tucker, John L., Urban, Frank J., Vazquez, Enrique, Wei, Lulin

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The use of borane–amine adducts as versatile palladium-catalyzed hydrogen-transfer reagents in methanol von Couturier, Michel, Andresen, Brian M, Tucker, John L, Dubé, Pascal, Brenek, Steven J, Negri, Joanna T

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5,5-Dimethyl-1,4,2-dioxazoles as Versatile Aprotic Hydroxamic Acid Protecting Groups von Couturier, Michel, Tucker, John L, Proulx, Caroline, Boucher, Ghislain, Dubé, Pascal, Andresen, Brian M, Ghosh, Arun

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Palladium catalyzed activation of borane–amine adducts: rate enhancement of amine–borane methanolysis in the reduction of nitrobenzenes to anilines von Couturier, Michel, Tucker, John L, Andresen, Brian M, Dubé, Pascal, Brenek, Steven J, Negri, Joanna T

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Process Enabling and the Scale-Up of 6β-Hydroxymethylsulbactam and Its Esters von Norris, Timothy, Ripin, David H. Brown, Ahlijanian, Paul, Andresen, Brian M, Barrila, Mark T, Colon-Cruz, Roberto, Couturier, Michel, Hawkins, Joel M, Loubkina, Ioulia V, Rutherford, Jennifer, Stickley, Kurt, Wei, Lulin, Vollinga, Roel, de Pater, Robert, Maas, Peter, de Lange, Ben, Callant, Dominique, Konings, Jeroen, Andrien, Jean, Versleijen, Jos, Hulshof, Jos, Daia, Elena, Johnson, Natalka, Sung, David W. L

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Practical Large-Scale Synthesis of 3,4-Isopropylidenedioxypyrrolidine Hydrotosylate:  Atom Economical Self-Hydrogenolysis of a Crystalline Borane−Benzylamine Adduct von Couturier, Michel, Andresen, Brian M, Jorgensen, Jeffrey B, Tucker, John L, Busch, Frank R, Brenek, Steven J, Dubé, Pascal, am Ende, David J, Negri, Joanna T

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Chemoselective Removal of Dimeric 1,3-Diol Impurities Generated from Methyl Grignard Addition onto Esters von Tucker, John L, Couturier, Michel, Leeman, Kyle R, Hinderaker, Matthew P, Andresen, Brian M

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Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate von Brian M. Andresen, Brian C. Vanderplas, John L. Tucker, Janice E. Sieser, Maxime Riou, Teresa M. Makowski, Joel M. Hawkins, Melina Girardin, Arun Ghosh, Kristina Dupont-Gaudet, Nga M. Do, Keith M. DeVries, Michel Couturier, Stéphane Caron, Timothy J.N. Watson

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Efficient synthesis of the κ-opioid receptor agonist CJ-15,161: four stereospecific inversions at a single aziridinium stereogenic center von Couturier, Michel, Tucker, John L., Andresen, Brian M., DeVries, Keith M., Vanderplas, Brian C., Ito, Fumitaka

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Cyclic di-nucleotide compounds as sting agonists von Lu, Min, Trotter, Benjamin Wesley, Chang, Wonsuk, Cumming, Jared N, Bennett, Frank, Lim, Jongwon, Wu, Wen-Lian, Andresen, Brian M, Childers, Matthew Lloyd

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CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS von TROTTER, Benjamin, Wesley, CUMMING, Jared, N, WU, Wen-Lian, CHILDERS, Matthew, Lloyd, LIM, Jongwon, LU, Min, ANDRESEN, Brian, M, BENNETT, Frank, CHANG, Wonsuk

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CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS von Lu, Min, Trotter, Benjamin Wesley, Chang, Wonsuk, Cumming, Jared N, Bennett, Frank, Lim, Jongwon, Wu, Wen-Lian, Andresen, Brian M, Childers, Matthew Lloyd

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THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS von ELLIS, John Michael, GAUTHIER, Jacques Yves, BUTCHER, John W, ARRINGTON, Kenneth L, NORTHRUP, Alan B, ANDRESEN, Brian M, OTTE, Ryan D, FOURNIER, Jean-Francois, ROBICHAUD, Joel S

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CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS von TROTTER, Benjamin, Wesley, CUMMING, Jared, N, WU, Wen-Lian, CHILDERS, Matthew, Lloyd, LIM, Jongwon, LU, Min, ANDRESEN, Brian, M, BENNETT, Frank, CHANG, Wonsuk

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TERTIARY ALCOHOL IMIDAZOPYRAZINE BTK INHIBITORS von BOGA, Sobhana Babu, WANG, Dahai, WU, Hao, CAI, Jiaqiang, YANG, Chundao, KOZLOWSKI, Joseph, A, ANDRESEN, Brian, M, GAO, Xiaolei, GUIADEEN, Deodialsingh, LIU, Jian

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