Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review von Antoniou, Miranta, Jorgensen, Andrea L, Kolamunnage-Dona, Ruwanthi

Volltext

Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis von Jorgensen, Andrea L, FitzGerald, Richard J, Oyee, James, Pirmohamed, Munir, Williamson, Paula R

Volltext

Warfarin dosing algorithms: A systematic review von Asiimwe, Innocent G., Zhang, Eunice J., Osanlou, Rostam, Jorgensen, Andrea L., Pirmohamed, Munir

Volltext

STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline von Chaplin, Marty, Kirkham, Jamie J., Dwan, Kerry, Sloan, Derek J., Davies, Geraint, Jorgensen, Andrea L.

Volltext

A Randomized Trial of Genotype-Guided Dosing of Warfarin von Pirmohamed, Munir, Burnside, Girvan, Eriksson, Niclas, Jorgensen, Andrea L, Toh, Cheng Hock, Nicholson, Toby, Kesteven, Patrick, Christersson, Christina, Wahlström, Bengt, Stafberg, Christina, Zhang, J. Eunice, Leathart, Julian B, Kohnke, Hugo, Maitland-van der Zee, Anke H, Williamson, Paula R, Daly, Ann K, Avery, Peter, Kamali, Farhad, Wadelius, Mia

Volltext

Benchmarking UMI-aware and standard variant callers for low frequency ctDNA variant detection von Maruzani, Rugare, Brierley, Liam, Jorgensen, Andrea, Fowler, Anna

Volltext

Joint modelling of time-to-event and multivariate longitudinal outcomes: recent developments and issues von Hickey, Graeme L, Philipson, Pete, Jorgensen, Andrea, Kolamunnage-Dona, Ruwanthi

Volltext

Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy von Alfirevic, Zarko, Stampalija, Tamara, Roberts, Devender, Jorgensen, Andrea L

Volltext

Genetic Determinants of Thiazide‐Induced Hyperuricemia, Hyperglycemia, and Urinary Electrolyte Disturbances – A Genome‐Wide Evaluation of the UK Biobank von Asiimwe, Innocent G., Walker, Lauren, Sofat, Reecha, Jorgensen, Andrea L., Pirmohamed, Munir

Volltext

Local cefuroxime tissue concentrations in the hand after single and repeated administration to 16 patients undergoing trapeziectomy: a randomized controlled trial von Jørgensen, Andrea René, Hanberg, Pelle, Bue, Mats, Hartig-Andreasen, Charlotte, Jørgensen, Nis Pedersen, Stilling, Maiken

Volltext

joineRML: a joint model and software package for time-to-event and multivariate longitudinal outcomes von Hickey, Graeme L, Philipson, Pete, Jorgensen, Andrea, Kolamunnage-Dona, Ruwanthi

Volltext

Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study von Jorgensen, Andrea L, Prince, Clare, Fitzgerald, Gail, Hanson, Anita, Downing, Jennifer, Reynolds, Julia, Zhang, J Eunice, Alfirevic, Ana, Pirmohamed, Munir

Volltext

Cardiovascular drugs and COVID‐19 clinical outcomes: A living systematic review and meta‐analysis von Asiimwe, Innocent G., Pushpakom, Sudeep, Turner, Richard M., Kolamunnage‐Dona, Ruwanthi, Jorgensen, Andrea L., Pirmohamed, Munir

Volltext

Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population von Carr, Daniel F., Chaponda, Mas, Jorgensen, Andrea L., Castro, Elena Cornejo, van Oosterhout, Joep J., Khoo, Saye H., Lalloo, David G., Heyderman, Robert S., Alfirevic, Ana, Pirmohamed, Munir

Volltext

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients von Asiimwe, Innocent G., Blockman, Marc, Cohen, Karen, Cupido, Clint, Hutchinson, Claire, Jacobson, Barry, Lamorde, Mohammed, Morgan, Jennie, Mouton, Johannes P., Nakagaayi, Doreen, Okello, Emmy, Schapkaitz, Elise, Sekaggya-Wiltshire, Christine, Semakula, Jerome R., Waitt, Catriona, Zhang, Eunice J., Jorgensen, Andrea L., Pirmohamed, Munir

Volltext

SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes von Syed, Hamzah, Jorgensen, Andrea L, Morris, Andrew P

Volltext

Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink von Carr, Daniel F., Francis, Ben, Jorgensen, Andrea L., Zhang, Eunice, Chinoy, Hector, Heckbert, Susan R., Bis, Joshua C., Brody, Jennifer A., Floyd, James S., Psaty, Bruce M., Molokhia, Mariam, Lapeyre‐Mestre, Maryse, Conforti, Anita, Alfirevic, Ana, Staa, Tjeerd, Pirmohamed, Munir

Volltext

A multi-factorial analysis of response to warfarin in a UK prospective cohort von Bourgeois, Stephane, Jorgensen, Andrea, Zhang, Eunice J, Hanson, Anita, Gillman, Matthew S, Bumpstead, Suzannah, Toh, Cheng Hock, Williamson, Paula, Daly, Ann K, Kamali, Farhad, Deloukas, Panos, Pirmohamed, Munir

Volltext

Cardiovascular drugs and COVID‐19 clinical outcomes: a systematic review and meta‐analysis of randomized controlled trials von Asiimwe, Innocent G., Pushpakom, Sudeep P., Turner, Richard M., Kolamunnage‐Dona, Ruwanthi, Jorgensen, Andrea L., Pirmohamed, Munir

Volltext

Effects of tourniquet inflation on peri- and postoperative cefuroxime concentrations in bone and tissue von Hanberg, Pelle, Bue, Mats, Kabel, Jesper, Jørgensen, Andrea René, Jessen, Christian, Søballe, Kjeld, Stilling, Maiken

Volltext