Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability—A literature review von Frassetto, Andrea, Breschi, Lorenzo, Turco, Gianluca, Marchesi, Giulio, Di Lenarda, Roberto, Tay, Franklin R, Pashley, David H, Cadenaro, Milena

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Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms von Lin, Hua V, Frassetto, Andrea, Kowalik, Jr, Edward J, Nawrocki, Andrea R, Lu, Mofei M, Kosinski, Jennifer R, Hubert, James A, Szeto, Daphne, Yao, Xiaorui, Forrest, Gail, Marsh, Donald J

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Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates von Zhu, Xuling, Yin, Ling, Theisen, Matt, Zhuo, Jenny, Siddiqui, Summar, Levy, Becca, Presnyak, Vladimir, Frassetto, Andrea, Milton, Jaclyn, Salerno, Timothy, Benenato, Kerry E., Milano, Joe, Lynn, Andy, Sabnis, Staci, Burke, Kristine, Besin, Gilles, Lukacs, Christine M., Guey, Lin T., Finn, Patrick F., Martini, Paolo G.V.

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Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia von Jiang, Lei, Park, Ji-Sun, Yin, Ling, Laureano, Rodrigo, Jacquinet, Eric, Yang, Jinsong, Liang, Shi, Frassetto, Andrea, Zhuo, Jenny, Yan, Xinhua, Zhu, Xuling, Fortucci, Steven, Hoar, Kara, Mihai, Cosmin, Tunkey, Christopher, Presnyak, Vlad, Benenato, Kerry E., Lukacs, Christine M., Martini, Paolo G. V., Guey, Lin T.

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Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia von An, Ding, Schneller, Jessica L., Frassetto, Andrea, Liang, Shi, Zhu, Xuling, Park, Ji-Sun, Theisen, Matt, Hong, Sue-Jean, Zhou, Jenny, Rajendran, Raj, Levy, Becca, Howell, Rebecca, Besin, Gilles, Presnyak, Vladimir, Sabnis, Staci, Murphy-Benenato, Kerry E., Kumarasinghe, E. Sathyajith, Salerno, Timothy, Mihai, Cosmin, Lukacs, Christine M., Chandler, Randy J., Guey, Lin T., Venditti, Charles P., Martini, Paolo G.V.

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Adhesive performance of a multi-mode adhesive system: 1-Year in vitro study von Marchesi, Giulio, Frassetto, Andrea, Mazzoni, Annalisa, Apolonio, Fabianni, Diolosà, Marina, Cadenaro, Milena, Di Lenarda, Roberto, Pashley, David H, Tay, Franklin, Breschi, Lorenzo

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Systemic modified messenger RNA for replacement therapy in alpha 1-antitrypsin deficiency von Karadagi, Ahmad, Cavedon, Alex G., Zemack, Helen, Nowak, Greg, Eybye, Marianne E., Zhu, Xuling, Guadagnin, Eleonora, White, Rebecca A., Rice, Lisa M., Frassetto, Andrea L., Strom, Stephen, Jorns, Carl, Martini, Paolo G. V., Ellis, Ewa

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Characterizing the mechanism of action for mRNA therapeutics for the treatment of propionic acidemia, methylmalonic acidemia, and phenylketonuria von Baek, Rena, Coughlan, Kimberly, Jiang, Lei, Liang, Min, Ci, Lei, Singh, Harkewal, Zhang, Hannah, Kaushal, Neeraj, Rajlic, Ivana Liric, Van, Linh, Dimen, Rain, Cavedon, Alexander, Yin, Ling, Rice, Lisa, Frassetto, Andrea, Guey, Lin, Finn, Patrick, Martini, Paolo G. V.

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mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency von Cao, Jingsong, An, Ding, Galduroz, Mikel, Zhuo, Jenny, Liang, Shi, Eybye, Marianne, Frassetto, Andrea, Kuroda, Eishi, Funahashi, Aki, Santana, Jordan, Mihai, Cosmin, Benenato, Kerry E., Kumarasinghe, E. Sathyajith, Sabnis, Staci, Salerno, Timothy, Coughlan, Kimberly, Miracco, Edward J., Levy, Becca, Besin, Gilles, Schultz, Joshua, Lukacs, Christine, Guey, Lin, Finn, Patrick, Furukawa, Tatsuhiko, Giangrande, Paloma H., Saheki, Takeyori, Martini, Paolo G.V.

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Long-term efficacy and safety of mRNA therapy in two murine models of methylmalonic acidemia von An, Ding, Frassetto, Andrea, Jacquinet, Eric, Eybye, Marianne, Milano, Joseph, DeAntonis, Christine, Nguyen, Vi, Laureano, Rodrigo, Milton, Jaclyn, Sabnis, Staci, Lukacs, Christine M., Guey, Lin T.

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Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice von Touramanidou, Loukia, Gurung, Sonam, Cozmescu, Claudiu A, Perocheau, Dany, Moulding, Dale, Finn, Patrick F, Frassetto, Andrea, Waddington, Simon N, Gissen, Paul, Baruteau, Julien

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Blood Wettability of Different Dental Implant Surfaces after Different Pre-Treatments: Ultrasonic Instrumentation, Platelet-Rich Fibrin Coating, and Acid Etching. An In Vitro Study von Bevilacqua, Lorenzo, Faccioni, Francesco, Porrelli, Davide, Faccioni, Paolo, Rusin, Francesco, Frassetto, Andrea, Maglione, Michele

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Ex vivo precision-cut liver slices model disease phenotype and monitor therapeutic response for liver monogenic diseases [version 2; peer review: 1 approved, 1 approved with reserv... von Perocheau, Dany, Gurung, Sonam, Touramanidou, Loukia, Duff, Claire, Sharma, Garima, Sebire, Neil, Finn, Patrick F, Cavedon, Alex, Siddiqui, Summar, Rice, Lisa, Martini, Paolo G.V., Frassetto, Andrea, Baruteau, Julien

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Sox3 Is Required for Gonadal Function, but Not Sex Determination, in Males and Females von Weiss, Jeffrey, Meeks, Joshua J., Hurley, Lisa, Raverot, Gerald, Frassetto, Andrea, Jameson, J. Larry

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Generation of a mouse model of Primary Hyperoxaluria Type 1 via CRISPR/Cas9 mediated gene editing von Coughlan, Kimberly, Maganti, Rajanikanth, Frassetto, Andrea, DeAntonis, Christine, Wolfrom, Meredith, Graham, Anne-Renee, Hillier, Shawn, Fortucci, Steven, Jandal, Hoor, Hong, Sue-Jean, Giangrande, Paloma, Martini, Paolo

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Risk Factors for Peri-Implantitis: Effect of History of Periodontal Disease and Smoking Habits. A Systematic Review and Meta-Analysis von Stacchi, Claudio, Berton, Federico, Perinetti, Giuseppe, Frassetto, Andrea, Lombardi, Teresa, Khoury, Aiman, Andolsek, Francesca, Di Lenarda, Roberto

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Systemic messenger RNA as an etiological treatment for acute intermittent porphyria von Jiang, Lei, Berraondo, Pedro, Jericó, Daniel, Guey, Lin T., Sampedro, Ana, Frassetto, Andrea, Benenato, Kerry E., Burke, Kristine, Santamaría, Eva, Alegre, Manuel, Pejenaute, Álvaro, Kalariya, Mayur, Butcher, William, Park, Ji-Sun, Zhu, Xuling, Sabnis, Staci, Kumarasinghe, E. Sathyajith, Salerno, Timothy, Kenney, Matthew, Lukacs, Christine M., Ávila, Matías A., Martini, Paolo G. V., Fontanellas, Antonio

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Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3 von Wei, Guangyan, Cao, Jingsong, Huang, Pinzhu, An, Ping, Badlani, Disha, Vaid, Kahini A., Zhao, Shuangshuang, Wang, David Q-H., Zhuo, Jenny, Yin, Ling, Frassetto, Andrea, Markel, Arianna, Presnyak, Vladimir, Gandham, Srujan, Hua, Serenus, Lukacs, Christine, Finn, Patrick F., Giangrande, Paloma H., Martini, Paolo G.V., Popov, Yury V.

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Characterization of an ornithine transcarbamylase conditional knockout mouse model: A novel model for understanding the effect of MRNA therapies for treatment of ornithine transcar... von Zimmer, Mike, Zhou, Jenny, Liang, Shi, Yin, Ling, Frassetto, Andrea, Graham, Anne-Renee, White, Rebecca, Principe, Maria, Palmer, Tiffany, Naidu, Shan, Jacquinet, Eric, Finn, Patrick, Martini, Paolo

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Improved therapeutic efficacy in two mouse models of methylmalonic acidemia (MMA) using a second-generation mRNA therapy von Coughlan, Kimberly A., Eybye, Marianne, Henderson, Nicholas, DeAntonis, Christine M., Frassetto, Andrea, Hanahoe, Erin, Ketova, Tatiana, Jacquinet, Eric, Presnyak, Vladimir, Jain, Ruchi, Marshall, John, Martini, Paolo G.V.

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