BACE1- and BACE2-expressing Human Cells von Andrau, David, Dumanchin-Njock, Cécile, Ayral, Erwan, Vizzavona, Jean, Farzan, Mike, Boisbrun, Michel, Fulcrand, Pierre, Hernandez, Jean-François, Martinez, Jean, Lefranc-Jullien, Solveig, Checler, Frédéric

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BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in... von Andrau, David, Dumanchin-Njock, Cecile, Ayral, Erwan, Vizzavona, Jean, Farzan, Mike, Boisbrun, Michel, Fulcrand, Pierre, Hernandez, Jean-Francois, Martinez, Jean, Lefranc-Jullien, Solveig, Checler, Frederic

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Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase - Reponse von Petit, Agnes, Dumanchin-Njock, Cécile, Andrau, David, da Costa, Cristine Alves, Checler, Frédéric

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Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase von Esler, William P, Das, Chittaranjan, Campbell, William A, Kimberly, W. Taylor, Kornilova, Anna Y, Diehl, Thekla S, Ye, Wenjuan, Ostaszewski, Beth L, Xia, Weiming, Selkoe, Dennis J, Wolfe, Michael S

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Amyloid-lowering isocoumarins are not direct inhibitors of [gamma]-secretase - Reponse von Petit, Agnes, Dumanchin-Njock, Cécile, Andrau, David, Cristine Alves da Costa, Checler, Frédéric

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Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals von Shah, Nilay, Maqbool, Muhammad Ahmad, Yahia, Yousra, El Aabidine, Amal Zine, Esnault, Cyril, Forné, Ignasi, Decker, Tim-Michael, Martin, David, Schüller, Roland, Krebs, Stefan, Blum, Helmut, Imhof, Axel, Eick, Dirk, Andrau, Jean-Christophe

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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions von Esnault, Cyril, Magat, Talha, Zine El Aabidine, Amal, Garcia-Oliver, Encar, Cucchiarini, Anne, Bouchouika, Soumya, Lleres, David, Goerke, Lutz, Luo, Yu, Verga, Daniela, Lacroix, Laurent, Feil, Robert, Spicuglia, Salvatore, Mergny, Jean-Louis, Andrau, Jean-Christophe

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Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene von Alomairi, Jaafar, Molitor, Anne M, Sadouni, Nori, Hussain, Saadat, Torres, Magali, Saadi, Wiam, Dao, Lan T M, Charbonnier, Guillaume, Santiago-Algarra, David, Andrau, Jean Christophe, Puthier, Denis, Sexton, Tom, Spicuglia, Salvatore

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Abnormal Immune Profile in Individuals with Kabuki Syndrome von Comel, Margot, Saad, Norma, Sil, Debapratim, Apparailly, Florence, Willems, Marjolaine, Djouad, Farida, Andrau, Jean-Christophe, Lozano, Claire, Genevieve, David

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Iron Deficiency in Patients with Inflammatory Bowel Diseases: A Prospective Multicenter Cross-Sectional Study von Peyrin-Biroulet, Laurent, Bouguen, Guillaume, Laharie, David, Pellet, Gauthier, Savoye, Guillaume, Gilletta, Cyrielle, Michiels, Christophe, Buisson, Anthony, Fumery, Mathurin, Trochu, Jean-Noël, Cacoub, Patrice

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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions von Esnault, Cyril, Magat, Talha, Zine El Aabidine, Amal, Garcia-Oliver, Encar, Cucchiarini, Anne, Bouchouika, Soumya, Llères, David, Goerke, Lutz, Luo, Yu, Verga, Daniela, Lacroix, Laurent, Feil, Robert, Spicuglia, Salvatore, Mergny, Jean-Louis, Andrau, Jean-Christophe

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Randomized Phase II Trial Evaluating Two Sequential Treatments in First Line of Metastatic Pancreatic Cancer: Results of the PANOPTIMOX-PRODIGE 35 Trial von Dahan, Laetitia, Williet, Nicolas, Le Malicot, Karine, Phelip, Jean-Marc, Desrame, Jérôme, Bouché, Olivier, Petorin, Caroline, Malka, David, Rebischung, Christine, Aparicio, Thomas, Lecaille, Cédric, Rinaldi, Yves, Turpin, Anthony, Bignon, Anne-Laure, Bachet, Jean-Baptiste, Seitz, Jean-François, Lepage, Come, François, Eric

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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions von Esnault, Cyril, Magat, Talha, Aabidine, Amal Zine El, Garcia-Oliver, Encar, Cucchiarini, Anne, Bouchouika, Soumya, Llères, David, Goerke, Lutz, Luo, Yu, Verga, Daniela, Lacroix, Laurent, Feil, Robert, Spicuglia, Salvatore, Mergny, Jean‐louis, Andrau, Jean Christophe

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1179 PERSISTENCE, EFFICACY AND TOLERANCE OF SUBCUTANEOUS INFLIXIMAB AFTER SWITCH FROM INTRAVENOUS INFLIXIMAB IN IBD PATIENTS IN REMISSION:: ONE-TEAR RESULTS FROM A MULTICENTER PROS... von Mathieu, Nicolas, Heluwaert, Frédéric, Rivière, Pauline, Hebuterne, Xavier, Chupin, Antoine, Abitbol, Vered, Guillaume, Bouguen, Vuitton, Lucine, Allez, Matthieu, Montuclard, Celine, Nancey, Stephane, Biron, Amelie, Wils, Pauline, Gilletta, Cyrielle, de Maissin, Astrid, Altwegg, Romain, Chanteloup, Elise, Plastaras, Laurianne, Soune, Philippe Ah, Bourreille, Arnaud, Bouhnik, Yoram, Seksik, Philippe, Simon, Marion, Uzzan, Mathieu, andrau, Pierre, Rouillon, Clea, Arondel, Yves, Peyrin-Biroulet, Laurent, Laharie, David, Vicaut, Eric, Hupé, Marianne

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Tu1768 PERSISTENCE OF SUBCUTANEOUS INFLIXIMAB AFTER SWITCHING FROM INTRAVENOUS IN A FRENCH NATIONAL COHORT OF IBD PATIENTS IN REMISSION von Mathieu, Nicolas, Rivière, Pauline, Heluwaert, Frédéric, Hebuterne, Xavier, Chupin, Antoine, Guillaume, Bouguen, Vuitton, Lucine, Allez, Matthieu, montuclard, celine, Nachury, Maria, Nancey, Stephane, Biron, Amelie, Giletta, Cyrielle, Abitbol, Vered, Altwegg, Romain, de maissin, astrid, Plastaras, Laurianne, Soune, Philippe Ah, Bourreille, Arnaud, Bouhnik, Yoram, Seksik, Philippe, chanteloup, Elise, Simon, Marion, Uzzan, Mathieu, andrau, Pierre, Rouillon, Clea, arondel, yves, Peyrin-Biroulet, Laurent, Laharie, David

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Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors von Axford, Lorraine C., Agarwal, Piyush K., Anderson, Kelly H., Andrau, Laura N., Atherall, John, Barker, Stephanie, Bennett, James M., Blair, Michael, Collins, Ian, Czaplewski, Lloyd G., Davies, David T., Gannon, Carlie T., Kumar, Dushyant, Lancett, Paul, Logan, Alastair, Lunniss, Christopher J., Mitchell, Dale R., Offermann, Daniel A., Palmer, James T., Palmer, Nicholas, Pitt, Gary R.W., Pommier, Stéphanie, Price, Daniel, Narasinga Rao, B., Saxena, Rashmi, Shukla, Tarun, Singh, Amit K., Singh, Mahipal, Srivastava, Anil, Steele, Christopher, Stokes, Neil R., Thomaides-Brears, Helena B., Tyndall, Edward M., Watson, David, Haydon, David J.

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Clinico-biological factors predicting the benefit of the LV5FU2 maintenance strategy as a first-line therapy in patients with metastatic pancreatic cancer von Boisteau, Emeric, Dahan, Laetitia, Williet, Nicolas, Le Malicot, Karine, Desramé, Jérôme, Bouché, Olivier, Petorin, Caroline, Malka, David, Rebischung, Christine, Aparicio, Thomas, Lecaille, Cédric, Rinaldi, Yves, Turpin, Anthony, Bignon, Anne-Laure, Bachet, Jean-Baptiste, Lepage, Côme, Granger, Victoire, Legoux, Jean-Louis, Deplanque, Gaël, Baconnier, Mathieu, Lecomte, Thierry, Bonnet, Isabelle, Seitz, Jean-François, François, Eric, Lièvre, Astrid

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Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders von Aref-Eshghi, Erfan, Kerkhof, Jennifer, Pedro, Victor P., France, Groupe DI, Barat-Houari, Mouna, Ruiz-Pallares, Nathalie, Andrau, Jean-Christophe, Lacombe, Didier, Van-Gils, Julien, Fergelot, Patricia, Dubourg, Christéle, Cormier-Daire, Valerie, Rondeau, Sophie, Lecoquierre, François, Saugier-Veber, Pascale, Nicolas, Gaël, Lesca, Gaetan, Chatron, Nicolas, Sanlaville, Damien, Vitobello, Antonio, Faivre, Laurence, Thauvin-Robinet, Christel, Laumonnier, Frederic, Raynaud, Martine, Alders, Mariëlle, Mannens, Marcel, Henneman, Peter, Hennekam, Raoul C., Velasco, Guillaume, Francastel, Claire, Ulveling, Damien, Ciolfi, Andrea, Pizzi, Simone, Tartaglia, Marco, Heide, Solveig, Héron, Delphine, Mignot, Cyril, Keren, Boris, Whalen, Sandra, Afenjar, Alexandra, Bienvenu, Thierry, Campeau, Philippe M., Rousseau, Justine, Levy, Michael A., Brick, Lauren, Kozenko, Mariya, Balci, Tugce B., Siu, Victoria Mok, Stuart, Alan, Kadour, Mike, Masters, Jennifer, Takano, Kyoko, Kleefstra, Tjitske, de Leeuw, Nicole, Field, Michael, Shaw, Marie, Gecz, Jozef, Ainsworth, Peter J., Lin, Hanxin, Rodenhiser, David I., Friez, Michael J., Tedder, Matt, Lee, Jennifer A., DuPont, Barbara R., Stevenson, Roger E., Skinner, Steven A., Schwartz, Charles E., Genevieve, David, Sadikovic, Bekim

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Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs) von Burns, Christopher J., Bourke, David G., Andrau, Laura, Bu, Xianyong, Charman, Susan A., Donohue, Andrew C., Fantino, Emmanuelle, Farrugia, Michelle, Feutrill, John T., Joffe, Max, Kling, Marcel R., Kurek, Margarita, Nero, Tracy L., Nguyen, Thao, Palmer, James T., Phillips, Ian, Shackleford, David M., Sikanyika, Harrison, Styles, Michelle, Su, Stephen, Treutlein, Herbert, Zeng, Jun, Wilks, Andrew F.

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Design, synthesis and biological evaluation of I--substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors von Axford, Lorraine, Agarwal, Piyush, Anderson, Kelly, Andrau, Laura, Atherall, John, Barker, Stephanie, Bennett, James, Blair, Michael, Collins, Ian, Czaplewski, Lloyd, Davies, David, Gannon, Carlie, Kumar, Dushyant, Lancett, Paul, Logan, Alastair, Lunniss, Christopher, Mitchell, Dale, Offermann, Daniel, Palmer, James, Palmer, Nicholas, Pitt, Gary, Pommier, Stephanie, Price, Daniel, Rao, B, Saxena, Rashmi, Shukla, Tarun, Singh, Amit, Singh, Mahipal, Srivastava, Anil, Steele, Christopher, Stokes, Neil, Thomaides-Brears, Helena, Tyndall, Edward, Watson, David, Haydon, David

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