A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation von West, Jeffrey, Adler, Fred, Gallaher, Jill, Strobl, Maximilian, Brady-Nicholls, Renee, Brown, Joel, Roberson-Tessi, Mark, Kim, Eunjung, Noble, Robert, Viossat, Yannick, Basanta, David, Anderson, Alexander R A

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Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies von Gallaher, Jill A, Enriquez-Navas, Pedro M, Luddy, Kimberly A, Gatenby, Robert A, Anderson, Alexander R A

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Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes von Robertson-Tessi, Mark, Gillies, Robert J, Gatenby, Robert A, Anderson, Alexander R A

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Tumor Morphology and Phenotypic Evolution Driven by Selective Pressure from the Microenvironment von Anderson, Alexander R.A., Weaver, Alissa M., Cummings, Peter T., Quaranta, Vito

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Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution von Ibrahim-Hashim, Arig, Robertson-Tessi, Mark, Enriquez-Navas, Pedro M, Damaghi, Mehdi, Balagurunathan, Yoganand, Wojtkowiak, Jonathan W, Russell, Shonagh, Yoonseok, Kam, Lloyd, Mark C, Bui, Marilyn M, Brown, Joel S, Anderson, Alexander R A, Gillies, Robert J, Gatenby, Robert A

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Integrating Models to Quantify Environment-Mediated Drug Resistance von Picco, Noemi, Sahai, Erik, Maini, Philip K, Anderson, Alexander R A

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Unifying metastasis — integrating intravasation, circulation and end-organ colonization von Scott, Jacob, Kuhn, Peter, Anderson, Alexander R. A.

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Abstract SY36-03: Hijacking homeostatsis: How heterogeneity drives tumor progression and treatment failure von Anderson, Alexander RA

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A filter-flow perspective of haematogenous metastasis offers a non-genetic paradigm for personalised cancer therapy von Scott, Jacob G, Fletcher, Alexander G, Maini, Philip K, Anderson, Alexander R.A, Gerlee, Philip

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Abstract 6625: Mathematical modeling of single-cell data reveals the key role of stochasticity - not fitness - in determining the clonal origins of relapse in childhood leukemia von Turati, Virginia, Herrero, Javier, Robertson-Tessi, Mark, Enver, Tariq, Marusyk, Andriy, Anderson, Alexander RA

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Spatial analysis of recurrent glioblastoma reveals perivascular niche organization von Onubogu, Ugoma, Gatenbee, Chandler D, Prabhakaran, Sandhya, Wolfe, Kelsey L, Oakes, Benjamin, Salatino, Roberto, Vaubel, Rachael, Szentirmai, Oszkar, Anderson, Alexander Ra, Janiszewska, Michalina

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In silico analysis suggests differential response to bevacizumab and radiation combination therapy in newly diagnosed glioblastoma von Hawkins-Daarud, Andrea, Rockne, Russell, Corwin, David, Anderson, Alexander R. A., Kinahan, Paul, Swanson, Kristin R.

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Microenvironmental Independence Associated with Tumor Progression von ANDERSON, Alexander R. A, HASSANEIN, Mohamed, REYNOLDS, Albert B, QUARANTA, Vito, ESTRADA, Lourdes, WEAVER, Alissa M, BRANCH, Kevin M, LU, Jenny, LOBDELL, Nichole A, MAIER, Julie, BASANTA, David, WEIDOW, Brandy, NARASANNA, Archana, ARTEAGA, Carlos L

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Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model: e1004712 von Scott, Jacob G, Fletcher, Alexander G, Anderson, Alexander RA, Maini, Philip K

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NeoPredPipe: high-throughput neoantigen prediction and recognition potential pipeline von Schenck, Ryan O, Lakatos, Eszter, Gatenbee, Chandler, Graham, Trevor A, Anderson, Alexander R A

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Dependence of Invadopodia Function on Collagen Fiber Spacing and Cross-Linking: Computational Modeling and Experimental Evidence von Enderling, Heiko, Alexander, Nelson R., Clark, Emily S., Branch, Kevin M., Estrada, Lourdes, Crooke, Cornelia, Jourquin, Jérôme, Lobdell, Nichole, Zaman, Muhammad H., Guelcher, Scott A., Anderson, Alexander R.A., Weaver, Alissa M.

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Abstract B05: Harnessing heterogeneity to design better combination therapies von Robertson-Tessi, Mark, Gillies, Robert J., Gatenby, Robert A., Anderson, Alexander RA

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Linking changes in epithelial morphogenesis to cancer mutations using computational modeling von Rejniak, Katarzyna A, Wang, Shizhen E, Bryce, Nicole S, Chang, Hang, Parvin, Bahram, Jourquin, Jerome, Estrada, Lourdes, Gray, Joe W, Arteaga, Carlos L, Weaver, Alissa M, Quaranta, Vito, Anderson, Alexander R A

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Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance: e1004493 von Nichol, Daniel, Jeavons, Peter, Fletcher, Alexander G, Bonomo, Robert A, Maini, Philip K, Paul, Jerome L, Gatenby, Robert A, Anderson, Alexander RA, Scott, Jacob G

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Microenvironmental Variables Must Influence Intrinsic Phenotypic Parameters of Cancer Stem Cells to Affect Tumourigenicity: e1003433 von Scott, Jacob G, Hjelmeland, Anita B, Chinnaiyan, Prakash, Anderson, Alexander RA, Basanta, David

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