WNT signalling pathways as therapeutic targets in cancer von Anastas, Jamie N., Moon, Randall T.

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Histone Serotonylation: Can the Brain Have “Happy” Chromatin? von Anastas, Jamie N., Shi, Yang

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Histone Lysine Demethylase Inhibitors von Jambhekar, Ashwini, Anastas, Jamie N, Shi, Yang

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Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG von Anastas, Jamie N., Zee, Barry M., Kalin, Jay H., Kim, Mirhee, Guo, Robyn, Alexandrescu, Sanda, Blanco, Mario Andres, Giera, Stefanie, Gillespie, Shawn M., Das, Jayanta, Wu, Muzhou, Nocco, Sarah, Bonal, Dennis M., Nguyen, Quang-De, Suva, Mario L., Bernstein, Bradley E., Alani, Rhoda, Golub, Todd R., Cole, Philip A., Filbin, Mariella G., Shi, Yang

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Applying single cell multi-omic analyses to understand treatment resistance in pediatric high grade glioma von Murdaugh, Rebecca L, Anastas, Jamie N

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Functional crosstalk between WNT signaling and tyrosine kinase signaling in cancer von Anastas, Jamie N

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Functional crosstalk between WNT signaling and tyrosine kinase signaling in cancer: Seminars in Oncology, Vol 42, No 6, December 2015, pp 820-831 von Anastas, Jamie N.

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Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling von Berndt, Jason D, Aoyagi, Atsushi, Yang, Peitzu, Anastas, Jamie N, Tang, Lan, Moon, Randall T

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Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation von Willis, Gareth R., Fernandez-Gonzalez, Angeles, Anastas, Jamie, Vitali, Sally H., Liu, Xianlan, Ericsson, Maria, Kwong, April, Mitsialis, S. Alex, Kourembanas, Stella

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SOD1 is a synthetic-lethal target in PPM1D -mutant leukemia cells von Zhang, Linda, Hsu, Joanne I, Braekeleer, Etienne D, Chen, Chun-Wei, Patel, Tajhal D, Martell, Alejandra G, Guzman, Anna G, Wohlan, Katharina, Waldvogel, Sarah M, Uryu, Hidetaka, Tovy, Ayala, Callen, Elsa, Murdaugh, Rebecca L, Richard, Rosemary, Jansen, Sandra, Vissers, Lisenka, de Vries, Bert B A, Nussenzweig, Andre, Huang, Shixia, Coarfa, Cristian, Anastas, Jamie, Takahashi, Koichi, Vassiliou, George, Goodell, Margaret A

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RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma von Jiao, Fangfang, Li, Ze, He, Chen, Xu, Wenqi, Yang, Gensheng, Liu, Tingting, Shen, Hongjie, Cai, Jiajun, Anastas, Jamie N, Mao, Ying, Yu, Yongchun, Lan, Fei, Shi, Yujiang Geno, Jones, Chris, Xu, Yanhui, Baker, Suzanne J, Shi, Yang, Guo, Rui

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WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors von Anastas, Jamie N, Kulikauskas, Rima M, Tamir, Tigist, Rizos, Helen, Long, Georgina V, von Euw, Erika M, Yang, Pei-Tzu, Chen, Hsiao-Wang, Haydu, Lauren, Toroni, Rachel A, Lucero, Olivia M, Chien, Andy J, Moon, Randall T

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WLS inhibits melanoma cell proliferation through the β‐catenin signalling pathway and induces spontaneous metastasis von Yang, Pei‐Tzu, Anastas, Jamie N., Toroni, Rachel A., Shinohara, Michi M., Goodson, Jamie M., Bosserhoff, Anja K., Chien, Andy J., Moon, Randall T.

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Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation von Willis, Gareth R, Fernandez-Gonzalez, Angeles, Anastas, Jamie, Vitali, Sally H, Liu, Xianlan, Ericsson, Maria, Kwong, April, Mitsialis, S Alex, Kourembanas, Stella

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DDDR-44. REPURPOSING SSRI/SNRI TARGETING NEUROTRANSMITTER SIGNALING TO OVERCOME RESISTANCE TO CDK9 INHIBITORS IN DIFFUSE MIDLINE GLIOMA von Murdaugh, Rebecca L, Eberl, Brittany R, Richard, Rosemary U, Tremblay, Jack, Dei-Ampeh, Alfred, Anastas, Jamie N

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EXTH-47. ENHANCING GD2.CART THERAPY FOR DIFFUSE MIDLINE GLIOMA WITH LSD1 AND HDAC INHIBITORS von Murdaugh, Rebecca, Shekar, Meghan, Eberl, Brittany, Tremblay, Jack, Richard, Rosemary, Harmanci, Akdes Serin, Omer, Bilal, Anastas, Jamie

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DIPG-74. TARGETING TRANSCRIPTIONAL DYSREGULATION IN DMG THROUGH CDK9 AND HDAC INHIBITOR COMBINATION THERAPY von Eberl, Brittany R, Murdaugh, Rebecca L, Nnyagu, Adanze N, Richard, Rosemary U, Deneen, Benjamin, Yu, Kwanha, Anastas, Jamie N

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DIPG-45. ELONGIN B REGULATES H3K27M CHROMATIN INCORPORATION TO PROMOTE MALIGNANCY IN DIFFUSE MIDLINE GLIOMA von Anastas, Jamie, Kebede, Adam, Jiao, Alan, Mimoso, Claudia, Murdaugh, Rebecca, Zee, Barry, Filbin, Mariella, Adelman, Karen, Shi, Yang

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IMMU-18. ENHANCING GD2.CAR T CELL THERAPY FOR DIFFUSE MIDLINE GLIOMA WITH LSD1 AND HDAC INHIBITORS von Murdaugh, Rebecca L, Shekar, Meghan, Eberl, Brittany R, Tremblay, Jack R, Richard, Rosemary U, Nguyen, Linh, Omer, Bilal, Anastas, Jamie N

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MODL-12. REPURPOSING SSRI/SNRI TARGETING NEUROTRANSMITTER SIGNALING TO SENSITIZE DMG TO CDK9 INHIBITORS von Murdaugh, Rebecca L, Eberl, Brittany R, Richard, Rosemary U, Tremblay, Jack R, Dei-Ampeh, Alfred, Olson, Calla M, Anastas, Jamie N

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