Heterologous prime-boost: breaking the protective immune response bottleneck of COVID-19 vaccine candidates von He, Qian, Mao, Qunying, An, Chaoqiang, Zhang, Jialu, Gao, Fan, Bian, Lianlian, Li, Changgui, Liang, Zhenglun, Xu, Miao, Wang, Junzhi

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Boosting with heterologous vaccines effectively improves protective immune responses of the inactivated SARS-CoV-2 vaccine von Zhang, Jialu, He, Qian, An, Chaoqiang, Mao, Qunying, Gao, Fan, Bian, Lianlian, Wu, Xing, Wang, Qian, Liu, Pei, Song, Lifang, Huo, Yaqian, Liu, Siyuan, Yan, Xujia, Yang, Jinghuan, Cui, Bopei, Li, Changgui, Wang, Junzhi, Liang, Zhenglun, Xu, Miao

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Immunogenicity and protective efficacy of a recombinant protein subunit vaccine and an inactivated vaccine against SARS-CoV-2 variants in non-human primates von He, Qian, Mao, Qunying, Peng, Xiaozhong, He, Zhanlong, Lu, Shuaiyao, Zhang, Jialu, Gao, Fan, Bian, Lianlian, An, Chaoqiang, Yu, Wenhai, Yang, Fengmei, Zhou, Yanan, Yang, Yun, Li, Yanyan, Yuan, Yadi, Yan, Xujia, Yang, Jinghuan, Wu, Xing, Huang, Weijin, Li, Changgui, Wang, Junzhi, Liang, Zhenglun, Xu, Miao

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Transcriptomic analysis of the innate immune signatures of a SARS-CoV-2 protein subunit vaccine ZF2001 and an mRNA vaccine RRV von Wang, Qian, Song, Ziyang, Yang, Jinghuan, He, Qian, Mao, Qunying, Bai, Yu, Liu, Jianyang, An, Chaoqiang, Yan, Xujia, Cui, Bopei, Song, Lifang, Liu, Dong, Xu, Miao, Liang, Zhenglun

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A Novel Single-Stranded RNA-Based Adjuvant Improves the Immunogenicity of the SARS-CoV-2 Recombinant Protein Vaccine von Liu, Dong, An, Chaoqiang, Bai, Yu, Li, Kelei, Liu, Jianyang, Wang, Qian, He, Qian, Song, Ziyang, Zhang, Jialu, Song, Lifang, Cui, Bopei, Mao, Qunying, Jiang, Wei, Liang, Zhenglun

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Development of an ELISA Assay for the Determination of SARS-CoV-2 Protein Subunit Vaccine Antigen Content von Han, Lu, An, Chaoqiang, Liu, Dong, Wang, Zejun, Bian, Lianlian, He, Qian, Liu, Jianyang, Wang, Qian, Liu, Mingchen, Mao, Qunying, Hang, Taijun, Wang, Aiping, Gao, Fan, Tan, Dejiang, Liang, Zhenglun

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A Novel Targeted RIG-I Receptor 5′Triphosphate Double Strain RNA-Based Adjuvant Significantly Improves the Immunogenicity of the SARS-CoV-2 Delta-Omicron Chimeric RBD-Dimer Recombi... von Bai, Yu, An, Chaoqiang, Zhang, Xuanxuan, Li, Kelei, Cheng, Feiran, Cui, Bopei, Song, Ziyang, Liu, Dong, Zhang, Jialu, He, Qian, Liu, Jianyang, Mao, Qunying, Liang, Zhenglun

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A Short 5′triphosphate RNA nCoV-L Induces a Broad-Spectrum Antiviral Response by Activating RIG-I von Song, Ziyang, Wang, Qian, Bian, Lianlian, An, Chaoqiang, Cui, Bopei, Mao, Qunying, Wu, Xing, He, Qian, Bai, Yu, Liu, Jianyang, Song, Lifang, Liu, Dong, Zhang, Jialu, Gao, Fan, Li, Xiuling, Liang, Zhenglun

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Heterologous Omicron-adapted vaccine as a secondary booster promotes neutralizing antibodies against Omicron and its sub-lineages in mice von Liu, Jianyang, He, Qian, Gao, Fan, Bian, Lianlian, Wang, Qian, An, Chaoqiang, Song, Lifang, Zhang, Jialu, Liu, Dong, Song, Ziyang, Li, Lu, Bai, Yu, Wang, Zhongfang, Liang, Zhenglun, Mao, Qunying, Xu, Miao

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Non-neutralizing monoclonal antibody targeting VP2 EF loop of Coxsackievirus A16 can protect mice from lethal attack via Fc-dependent effector mechanism von Du, Ruixiao, An, Chaoqiang, Yao, Xin, Wang, Yiping, Wang, Ge, Gao, Fan, Bian, Lianlian, Hu, Yalin, Liu, Siyuan, Zhao, Qiaohui, Mao, Qunying, Liang, Zhenglun

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Heterologous immunization with adenovirus vectored and inactivated vaccines effectively protects against SARS-CoV-2 variants in mice and macaques von He, Qian, Mao, Qunying, Zhang, Jialu, Gao, Fan, Bai, Yu, Cui, Bopei, Liu, Jianyang, An, Chaoqiang, Wang, Qian, Yan, Xujia, Yang, Jinghuan, Song, Lifang, Song, Ziyang, Liu, Dong, Yuan, Yadi, Sun, Jing, Zhao, Jincun, Bian, Lianlian, Wu, Xing, Huang, Weijin, Li, Changgui, Wang, Junzhi, Liang, Zhenglun, Xu, Miao

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B.1.351 SARS-CoV-2 Variant Exhibits Higher Virulence but Less Viral Shedding than That of the Ancestral Strain in Young Nonhuman Primates von Bai, Yu, He, Qian, Yang, Jinghuan, Lu, Shuaiyao, Mao, Qunying, Gao, Fan, Bian, Lianlian, Zhang, Jialu, An, Chaoqiang, Liu, Jianyang, Wu, Xing, Yu, Wenhai, Wang, Zhongfang, Peng, Xiaozhong, Wang, Junzhi, Liang, Zhenglun, Xu, Miao

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Mixed formulation of mRNA and protein‐based COVID‐19 vaccines triggered superior neutralizing antibody responses von Zhang, Jialu, He, Qian, Yan, Xujia, Liu, Jianyang, Bai, Yu, An, Chaoqiang, Cui, Bopei, Gao, Fan, Mao, Qunying, Wang, Junzhi, Xu, Miao, Liang, Zhenglun

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Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors von Cui, Bopei, Song, Lifang, Wang, Qian, Li, Kelei, He, Qian, Wu, Xing, Gao, Fan, Liu, Mingchen, An, Chaoqiang, Gao, Qiushuang, Hu, Chaoying, Hao, Xiaotian, Dong, Fangyu, Zhou, Jiuyue, Liu, Dong, Song, Ziyang, Yan, Xujia, Zhang, Jialu, Bai, Yu, Mao, Qunying, Yang, Xiaoming, Liang, Zhenglun

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Establishment of the first Chinese national standard for protein subunit SARS-CoV-2 vaccine von Gao, Fan, An, Chaoqiang, Bian, Lianlian, Wang, Yiping, Zhang, Jialu, Cui, Bopei, He, Qian, Yuan, Yadi, Song, Lifang, Yang, Jinghuan, Yan, Xujia, Xu, Kangwei, Li, Changgui, Yao, Shanshan, Wu, Xing, Mao, Qunying, Liang, Zhenglun, Xu, Miao

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Resistin Induces Hypertension and Insulin Resistance in Mice via a TLR4-Dependent Pathway von Jiang, Yun, Lu, Linfang, Hu, Youtao, Li, Qiang, An, Chaoqiang, Yu, Xiaolan, Shu, Le, Chen, Ao, Niu, Congcong, Zhou, Lei, Yang, Zaiqing

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ER stress mediated degradation of diacylglycerol acyltransferase impairs mitochondrial functions in TMCO1 deficient cells von Wang, Xi, Wang, Qiao-Chu, Sun, Zhongshuai, Li, Tingting, Yang, Keyan, An, Chaoqiang, Guo, Caixia, Tang, Tie-Shan

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A Short 5'triphosphate RNA nCoV-L Induces a Broad-Spectrum Antiviral Response by Activating RIG-I von Song, Ziyang, Wang, Qian, Bian, Lianlian, An, Chaoqiang, Cui, Bopei, Mao, Qunying, Wu, Xing, He, Qian, Bai, Yu, Liu, Jianyang, Song, Lifang, Liu, Dong, Zhang, Jialu, Gao, Fan, Li, Xiuling, Liang, Zhenglun

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Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway von Zhou, Lei, Yu, Xiaolan, Meng, Qingjie, Li, Hongqiang, Niu, Congcong, Jiang, Yun, Cai, Yuxi, Li, Minghui, Li, Qiang, An, Chaoqiang, Shu, Le, Chen, Ao, Su, Handong, Tang, Yin, Yin, Shen, Raschke, Silja, Eckardt, Kristin, Eckel, Jürgen, Yang, Zaiqing

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A Novel Targeted RIG-I Receptor 5'Triphosphate Double Strain RNA-Based Adjuvant Significantly Improves the Immunogenicity of the SARS-CoV-2 Delta-Omicron Chimeric RBD-Dimer Recombi... von Bai, Yu, An, Chaoqiang, Zhang, Xuanxuan, Li, Kelei, Cheng, Feiran, Cui, Bopei, Song, Ziyang, Liu, Dong, Zhang, Jialu, He, Qian, Liu, Jianyang, Mao, Qunying, Liang, Zhenglun

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