Balancing the innate immune system in tumor development von Hagerling, Catharina, Casbon, Amy-Jo, Werb, Zena

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Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils von Casbon, Amy-Jo, Reynaud, Damien, Park, Chanhyuk, Khuc, Emily, Gan, Dennis D., Schepers, Koen, Passegué, Emmanuelle, Werb, Zena

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Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade von Pai, Chien-Chun Steven, Huang, John T., Lu, Xiaoqing, Simons, Donald M., Park, Chanhyuk, Chang, Anthony, Tamaki, Whitney, Liu, Eric, Roybal, Kole T., Seagal, Jane, Chen, Mingyi, Hagihara, Katsunobu, Wei, Xiao X., DuPage, Michel, Kwek, Serena S., Oh, David Y., Daud, Adil, Tsai, Katy K., Wu, Clint, Zhang, Li, Fasso, Marcella, Sachidanandam, Ravi, Jayaprakash, Anitha, Lin, Ingrid, Casbon, Amy-Jo, Kinsbury, Gillian A., Fong, Lawrence

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HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice von Devignes, Claire-Sophie, Aslan, Yetki, Brenot, Audrey, Devillers, Audrey, Schepers, Koen, Fabre, Stéphanie, Chou, Jonathan, Casbon, Amy-Jo, Werb, Zena, Provot, Sylvain

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Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations von Lohela, Marja, Casbon, Amy-Jo, Olow, Aleksandra, Bonham, Lynn, Branstetter, Daniel, Weng, Ning, Smith, Jeffrey, Werb, Zena

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NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice von Tian, Xiaoli, Sun, He, Casbon, Amy-Jo, Lim, Edward, Francis, Kevin P, Hellman, Judith, Prakash, Arun

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Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies von Noe, Paul, Wang, Joy H, Chung, Kyu, Cheng, Zhiyong, Field, Jessica J, Shen, Xiaomeng, Cortesio, Christa L, Pastuskovas, Cinthia V, Phee, Hyewon, Tarbell, Kristin V, Egen, Jackson G, Casbon, Amy-Jo

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Protective effects of matrix metalloproteinase-12 following corneal injury von Chan, Matilda F, Li, Jing, Bertrand, Anthony, Casbon, Amy-Jo, Lin, Jeffrey H, Maltseva, Inna, Werb, Zena

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Effects of IFN-γ on intracellular trafficking and activity of macrophage NADPH oxidase flavocytochrome b558 von Casbon, Amy‐Jo, Long, Matthew E., Dunn, Kenneth W., Allen, Lee‐Ann H., Dinauer, Mary C.

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Macrophage NADPH Oxidase Flavocytochrome b Localizes to the Plasma Membrane and Rab11-Positive Recycling Endosomes von Casbon, Amy-Jo, Allen, Lee-Ann H, Dunn, Kenneth W, Dinauer, Mary C

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Neutrophil-specific deletion of Syk results in recruitment-independent stabilization of the barrier and a long-term improvement in cognitive function after traumatic injury to the... von Trivedi, Alpa, Tercovich, Kayleen G., Casbon, Amy Jo, Raber, Jacob, Lowell, Clifford, Noble-Haeusslein, Linda J.

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Adaptive Immune Regulation of Mammary Postnatal Organogenesis von Plaks, Vicki, Boldajipour, Bijan, Linnemann, Jelena R., Nguyen, Nguyen H., Kersten, Kelly, Wolf, Yochai, Casbon, Amy-Jo, Kong, Niwen, van den Bijgaart, Renske J.E., Sheppard, Dean, Melton, Andrew C., Krummel, Matthew F., Werb, Zena

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Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity von Kim, Jennie C., Liu, Xian, Fitzgerald, Karen, Eng, Jason S., Orf, Jessica, O’Brien, Sarah A., Belmontes, Brian, Casbon, Amy-Jo, Novitskiy, Sergey V., Tarbell, Kristin V., DeVoss, Jason, Egen, Jackson G.

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Corrigendum: Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies von Noe, Paul, Wang, Joy H, Chung, Kyu, Cheng, Zhiyong, Field, Jessica J, Shen, Xiaomeng, Casey, Stephanie C, Cortesio, Christa L, Pastuskovas, Cinthia V, Phee, Hyewon, Tarbell, Kristin V, Egen, Jackson G, Casbon, Amy-Jo

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Delineating CSF-1-dependent regulation of myeloid cell diversity in tumors von Casbon, Amy-Jo, Lohela, Marja, Werb, Zena

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259 Discovery of synthetic signaling pathway receptors that increase the potency of CAR-T cells through optimized STAT activity von Gardner, Thomas J, Millare, Beatriz, Yao, Anzhi, Chen, Lan, Cass, Ashley, Mohanty, Suchismita, Chen, Jeremy, Gomez, Alma, DeTomaso, David, Ku, Manching, Berthoin, Lionel, Lim, Meng, Ong, Azalea, Thomas, Vince, Quant, Nicholas, Hsu, Brian, Casbon, Amy-Jo, Bezman, Natalie, Cooper, Aaron, Gray-Rupp, Levi, Boroughs, Angela, Nicholas Haining, W

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Abstract IA09: Building the metastatic microenvironment von Casbon, Amy-Jo, Plaks, Vicki, Werb, Zena

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Deletion Mutagenesis of p22phox Subunit of Flavocytochrome b558 von Zhu, Yanmin, Marchal, Christophe C., Casbon, Amy-Jo, Stull, Natalie, von Löhneysen, Katharina, Knaus, Ulla G., Jesaitis, Algirdas J., McCormick, Sally, Nauseef, William M., Dinauer, Mary C.

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Abstract 2981: Clonal deletion of tumor-specific T cells by combination checkpoint blockade compromises antitumor efficacy in low tumor burden states von Pai, Chien-Chun Steven, Lu, Xiaoqing, Simons, Donald, DuPage, Michel, Roybal, Kole T., Chen, Mingyi, Kwek, Serena, Casbon, Amy-Jo, Kinsbury, Gillian A., Fong, Lawrence

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Zena Werb (1945–2020) von Littlepage, Laurie E., Ewald, Andrew J., Alexander, Caroline, Casbon, Amy-Jo, Lu, Pengfei, Kessenbrock, Kai, Provot, Sylvain, Phillips, Joanna J., Kouros-Mehr, Hosein, Chan, Matilda, Welm, Bryan, Lilla, Jennifer N., Chou, Jonathan, Lawson, Devon, Lemieux, George, Plaks, Vicki, Egeblad, Mikala, Sternlicht, Mark

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