A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans von Tomalka, Jeffrey, Ganesan, Sandhya, Azodi, Elaheh, Patel, Krupen, Majmudar, Parth, Hall, Brian A, Fitzgerald, Katherine A, Hise, Amy G

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Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1 von Karmakar, Mausita, Sun, Yan, Hise, Amy G, Rietsch, Arne, Pearlman, Eric

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Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux von Karmakar, Mausita, Katsnelson, Michael, Malak, Hesham A, Greene, Neil G, Howell, Scott J, Hise, Amy G, Camilli, Andrew, Kadioglu, Aras, Dubyak, George R, Pearlman, Eric

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An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans von Hise, Amy G, Tomalka, Jeffrey, Ganesan, Sandhya, Patel, Krupen, Hall, Brian A, Brown, Gordon D, Fitzgerald, Katherine A

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Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection von Sun, Yan, Abbondante, Serena, Karmakar, Mausita, de Jesus Carrion, Steven, Che, Chengye, Hise, Amy G, Pearlman, Eric

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IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis von Conti, Heather R., Bruno, Vincent M., Childs, Erin E., Daugherty, Sean, Hunter, Joseph P., Mengesha, Bemnet G., Saevig, Danielle L., Hendricks, Matthew R., Coleman, Bianca M., Brane, Lucas, Solis, Norma, Cruz, J. Agustin, Verma, Akash H., Garg, Abhishek V., Hise, Amy G., Richardson, Jonathan P., Naglik, Julian R., Filler, Scott G., Kolls, Jay K., Sinha, Satrajit, Gaffen, Sarah L.

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Factors associated with severe human Rift Valley fever in Sangailu, Garissa County, Kenya von LaBeaud, A Desirée, Pfeil, Sarah, Muiruri, Samuel, Dahir, Saidi, Sutherland, Laura J, Traylor, Zachary, Gildengorin, Ginny, Muchiri, Eric M, Morrill, John, Peters, C J, Hise, Amy G, Kazura, James W, King, Charles H

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A Role for the Adaptor Proteins TRAM and TRIF in Toll-like Receptor 2 Signaling von Nilsen, Nadra J., Vladimer, Gregory I., Stenvik, Jørgen, Orning, M. Pontus A., Zeid-Kilani, Maria V., Bugge, Marit, Bergstroem, Bjarte, Conlon, Joseph, Husebye, Harald, Hise, Amy G., Fitzgerald, Katherine A., Espevik, Terje, Lien, Egil

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T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis von Martin, Bradley N, Wang, Chenhui, Zhang, Cun-jin, Kang, Zizhen, Gulen, Muhammet Fatih, Zepp, Jarod A, Zhao, Junjie, Bian, Guanglin, Do, Jeong-su, Min, Booki, Pavicic, Jr, Paul G, El-Sanadi, Caroline, Fox, Paul L, Akitsu, Aoi, Iwakura, Yoichiro, Sarkar, Anasuya, Wewers, Mark D, Kaiser, William J, Mocarski, Edward S, Rothenberg, Marc E, Hise, Amy G, Dubyak, George R, Ransohoff, Richard M, Li, Xiaoxia

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Inflammasomes in Aspergillosis—It Takes Two to Tango von Tomalka, Jeffrey, Hise, Amy G.

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β-Defensin 1 plays a role in acute mucosal defense against Candida albicans von Tomalka, Jeffrey, Azodi, Elaheh, Narra, Hema P, Patel, Krupen, O'Neill, Samantha, Cardwell, Cisley, Hall, Brian A, Wilson, James M, Hise, Amy G

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Innate Defense against Fungal Pathogens von Drummond, Rebecca A, Gaffen, Sarah L, Hise, Amy G, Brown, Gordon D

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Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans von Ganesan, Sandhya, Rathinam, Vijay A K, Bossaller, Lukas, Army, Kelly, Kaiser, William J, Mocarski, Edward S, Dillon, Christopher P, Green, Douglas R, Mayadas, Tanya N, Levitz, Stuart M, Hise, Amy G, Silverman, Neal, Fitzgerald, Katherine A

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Rift Valley fever virus infection induces activation of the NLRP3 inflammasome von Ermler, Megan E, Traylor, Zachary, Patel, Krupen, Schattgen, Stefan A, Vanaja, Sivapriya K, Fitzgerald, Katherine A, Hise, Amy G

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Association of symptoms and severity of rift valley fever with genetic polymorphisms in human innate immune pathways von Hise, Amy G, Traylor, Zachary, Hall, Noémi B, Sutherland, Laura J, Dahir, Saidi, Ermler, Megan E, Muiruri, Samuel, Muchiri, Eric M, Kazura, James W, LaBeaud, A Desirée, King, Charles H, Stein, Catherine M

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Bacterial Pathogen-associated Molecular Patterns Stimulate Biological Activity of Orthopaedic Wear Particles by Activating Cognate Toll-like Receptors von Greenfield, Edward M., Beidelschies, Michelle A., Tatro, Joscelyn M., Goldberg, Victor M., Hise, Amy G.

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MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases von Yu, Minjia, Zhou, Hao, Zhao, Junjie, Xiao, Nengming, Roychowdhury, Sanjoy, Schmitt, David, Hu, Bingqing, Ransohoff, Richard M, Harding, Clifford V, Hise, Amy G, Hazen, Stanley L, DeFranco, Anthony L, Fox, Paul L, Morton, Richard E, Dicorleto, Paul E, Febbraio, Maria, Nagy, Laura E, Smith, Jonathan D, Wang, Jian-an, Li, Xiaoxia

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TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis von Drage, Michael G., Pecora, Nicole D., Hise, Amy G., Febbraio, Maria, Silverstein, Roy L., Golenbock, Douglas T., Boom, W. Henry, Harding, Clifford V.

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Alcohol-Induced Liver Injury Is Modulated by Nlrp3 and Nlrc4 Inflammasomes in Mice von DeSantis, David A., Ko, Chih-wei, Liu, Yang, Liu, Xiuli, Hise, Amy G., Nunez, Gabriel, Croniger, Colleen M.

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Reduced Frequency of a CD14+ CD16+ Monocyte Subset with High Toll-Like Receptor 4 Expression in Cord Blood Compared to Adult Blood Contributes to Lipopolysaccharide Hyporesponsiven... von Pedraza-Sánchez, Sigifredo, Hise, Amy G., Ramachandra, Lakshmi, Arechavaleta-Velasco, Fabian, King, Christopher L.

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