Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the  phase 2 PANAMO trial von Lim, Endry H T, Vlaar, Alexander P J, Bos, Lieuwe D J, van Vught, Lonneke A, Boer, Anita M Tuip-de, Dujardin, Romein W G, Habel, Maria, Xu, Zhongli, Brouwer, Matthijs C, van de Beek, Diederik, de Bruin, Sanne

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Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands: A prospective cohort study von van Gils, Marit J, Lavell, Ayesha, van der Straten, Karlijn, Appelman, Brent, Bontjer, Ilja, Poniman, Meliawati, Burger, Judith A, Oomen, Melissa, Bouhuijs, Joey H, van Vught, Lonneke A, Slim, Marleen A, Schinkel, Michiel, Wynberg, Elke, van Willigen, Hugo D G, Grobben, Marloes, Tejjani, Khadija, van Rijswijk, Jacqueline, Snitselaar, Jonne L, Caniels, Tom G, Vlaar, Alexander P J, Prins, Maria, de Jong, Menno D, de Bree, Godelieve J, Sikkens, Jonne J, Bomers, Marije K, Sanders, Rogier W

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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths von Gervais, A, Philippot, Q, Manry, J, Michailidis, E, Parra-Martinez, A, Yang, R, Haljasmagi, L, Migaud, M, Sarekannu, K, Maslovskaja, J, de Prost, N, Tandjaoui-Lambiotte, Y, Poissy, J, Morel, P, Richard, P, Trouillet-Assant, S, Belot, A, Saker, K, Garcon, P, Lagier, JC, Gentile, S, Shaw, E, Morio, T, Tharaux, PL, Sene, D, Stepanian, A, Heath, JR, Franco, JL, Imberti, L, Biondi, A, Bonfanti, P, Castagnoli, R, Zhang, Y, Holland, SM, Biggs, CM, Lorenzo, L, Anglicheau, D, Haerynck, F, Nussbaum, RL, Keles, S, Bousfiha, AA, El Bakkouri, J, Ramirez-Santana, C, Pan-Hammarstrom, Q, Kurolap, A, Lampasona, V, Dominguez-Garrido, E, Vidigal, M, Zatz, M, van de Beek, D, Sahanic, S, Tancevski, I, Boyarchuk, O, Tangye, SG, Burrel, S, Duffy, D, Quintana-Murci, L, Klocperk, A, Shcherbina, A, Lau, YL, Chauvineau-Grenier, A, Venet, F, Monneret, G, Dyer, AH, Bourke, NM, Dorgham, K, Sedkaoui, SM, Rigo-Bonnin, R, Vinh, DC, Ostrowski, SR, Condino-Neto, A, Prando, C, Bondarenko, A, Spaan, AN, Gilardin, L, Fellay, J, Lyonnet, S, Lifton, RP, Mane, S, Anderson, MS, Andreakos, E, Pujol, A, Mogensen, TH, Mond, J, Debette, S, de Lamballerie, X, Gorochov, G, Solanich, X, Susen, S, Raoult, D, Gregersen, PK, Piemonti, L, Rodriguez-Gallego, C, Notarangelo, LD, Kisand, K, Okada, S, Rice, CM, Tiberghien, P, Zhang, Q, Abel, L

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The effect of immunosuppressive therapies on the endothelial host response in critically ill COVID-19 patients von Slim, M. A., Lim, E. H. T., van Vught, L. A., Boer, A. M. Tuip-de, Rademaker, E., Mulier, J. L. G. Haitsma, Engel, J. J., Pickkers, P., van de Veerdonk, F. L., Vlaar, A. P. J., Derde, L. P. G., Juffermans, N. P.

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Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity von Larsen, Mads Delbo, de Graaf, Erik L., Sonneveld, Myrthe E., Plomp, H. Rosina, Nouta, Jan, Hoepel, Willianne, Chen, Hung-Jen, Linty, Federica, Visser, Remco, Brinkhaus, Maximilian, Sustic, Tonci, de Taeye, Steven W., Bentlage, Arthur E. H., Toivonen, Suvi, Koeleman, Carolien A. M., Sainio, Susanna, Kootstra, Neeltje A., Brouwer, Philip J. M., Geyer, Chiara Elisabeth, Derksen, Ninotska I. L., Wolbink, Gertjan, de Winther, Menno, Sanders, Rogier W., van Gils, Marit J., de Bruin, Sanne, Vlaar, Alexander P. J., Rispens, Theo, den Dunnen, Jeroen, Zaaijer, Hans L., Wuhrer, Manfred, van dDer Schoot, C. Ellen, Vidarsson, Gestur

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Clinical features and prognostic factors in Covid-19: A prospective cohort study von de Bruin, Sanne, Bos, Lieuwe D., van Roon, Marian A., Tuip-de Boer, Anita M., Schuurman, Alex R., Koel-Simmelinck, Marleen J.A., Bogaard, Harm Jan, Tuinman, Pieter Roel, van Agtmael, Michiel A., Hamann, Jörg, Teunissen, Charlotte E., Wiersinga, W. Joost, (Koos) Zwinderman, A.H., Brouwer, Matthijs C., van de Beek, Diederik, Vlaar, Alexander P.J., van Agtmael, Michiel, Algera, Anne Geke, Appelman, Brent, van Baarle, Frank, Bax, Diane, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Buis, David T.P., Bugiani, Marianna, Bulle, Esther, Chouchane, Osoul, Cloherty, Alex, de Rotte, Maurits C.F.J., Dijkstra, Mirjam, Dongelmans, Dave A., Dujardin, Romein W.G., Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P., Hafkamp, Florianne, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M., Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W., de Jong, Menno D., Koning, Rutger, Lim, Endry H.T., van Mourik, Niels, Nellen, Jeannine, Nossent, Esther J., Paulus, Frederique, Peters, Edgar, Piña-Fuentes, Dan A.I., van der Poll, Tom, Preckel, Bennedikt, Prins, Jan M., Raasveld, Jorinde, Reijnders, Tom, Schinkel, Michiel, Schrauwen, Femke A.P., Schultz, Marcus J., Schuurmans, Alex, Schuurmans, Jaap, Sigaloff, Kim, Slim, Marleen A., Smeele, Patrick, Smit, Marry, Stijnis, Cornelis S., Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa M., Tuinman, Pieter R., van der Valk, Marc, Veelo, Denise, Volleman, Carolien, de Vries, Heder, Vught, Lonneke A., van Vugt, Michèle, Wouters, Dorien, Zwinderman, A.H (Koos), Brouwer, Matthijs C., Wiersinga, W. Joost, Vlaar, Alexander P.J.

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Association between dexamethasone treatment and the host response in COVID-19 patients admitted to the general ward von de Brabander, Justin, Michels, Erik H A, van Linge, Christine C A, Chouchane, Osoul, Douma, Renée A, Reijnders, Tom D Y, Schuurman, Alex R, van Engelen, Tjitske S R, Wiersinga, W Joost, van der Poll, Tom

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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies von Manry, Jérémy, Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Rosain, Jérémie, Philippot, Quentin, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Eto, Shohei, Garcia-Prat, Marina, Bizien, Lucy, Parra-Martínez, Alba, Yang, Rui, Haljasmägi, Liis, Migaud, Mélanie, Särekannu, Karita, Maslovskaja, Julia, de Prost, Nicolas, Tandjaoui-Lambiotte, Yacine, Luyt, Charles-Edouard, Amador-Borrero, Blanca, Gaudet, Alexandre, Poissy, Julien, Morel, Pascal, Richard, Pascale, Cognasse, Fabrice, Troya, Jesús, Trouillet-Assant, Sophie, Belot, Alexandre, Saker, Kahina, Garçon, Pierre, Rivière, Jacques G, Lagier, Jean-Christophe, Gentile, Stéphanie, Rosen, Lindsey B, Shaw, Elana, Morio, Tomohiro, Tanaka, Junko, Dalmau, David, Tharaux, Pierre-Louis, Sene, Damien, Stepanian, Alain, Mégarbane, Bruno, Triantafyllia, Vasiliki, Fekkar, Arnaud, Heath, James R, Franco, José Luis, Anaya, Juan-Manuel, Solé-Violán, Jordi, Imberti, Luisa, Biondi, Andrea, Bonfanti, Paolo, Castagnoli, Riccardo, Delmonte, Ottavia M, Zhang, Yu, Snow, Andrew L, Holland, Steven M, Biggs, Catherine M, Moncada-Vélez, Marcela, Arias, Andrés Augusto, Lorenzo, Lazaro, Boucherit, Soraya, Anglicheau, Dany, Planas, Anna M, Haerynck, Filomeen, Duvlis, Sotirija, Ozcelik, Tayfun, Keles, Sevgi, Bousfiha, Ahmed A, El Bakkouri, Jalila, Ramirez-Santana, Carolina, Paul, Stéphane, Pan-Hammarström, Qiang, Hammarström, Lennart, Dupont, Annabelle, Kurolap, Alina, Metz, Christine N, Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Ciceri, Fabio, Barreiros, Lucila A, Dominguez-Garrido, Elena, Vidigal, Mateus, Zatz, Mayana, van de Beek, Diederik, Sahanic, Sabina, Tancevski, Ivan, Stepanovskyy, Yurii, Boyarchuk, Oksana, Nukui, Yoko, Tsumura, Miyuki, Vidaur, Loreto, Tangye, Stuart G, Burrel, Sonia, Duffy, Darragh, Quintana-Murci, Lluis, Klocperk, Adam, Kann, Nelli Y, Shcherbina, Anna

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Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome von Kullberg, Robert F J, de Brabander, Justin, Boers, Leonoor S, Biemond, Jason J, Nossent, Esther J, Heunks, Leo M A, Vlaar, Alexander P J, Bonta, Peter I, van der Poll, Tom, Duitman, JanWillem, Bos, Lieuwe D J, Wiersinga, W Joost

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25-Hydroxyvitamin D concentrations do not affect the humoral or cellular immune response following SARS-CoV-2 mRNA vaccinations von Lavell, A.H.A., Schramade, A.E., Sikkens, J.J., van der Straten, K., van Dort, K.A., Slim, M.A., Appelman, B., van Vught, L.A., Vlaar, A.P.J., Kootstra, N.A., van Gils, M.J., Smulders, Y.M., de Jongh, R.T., Bomers, M.K., Appelman, Brent, Beek van de, Diederik, Bomers, Marije K., Brabander de, Justin, Brouwer, Matthijs C., Buis, David T.P., Chekrouni, Nora, Gils van, Marit J., Jong de, Menno D., Lavell, Ayesha H.A., Mourik van, Niels, Olie, Sabine E., Peters, Edgar J.G., Reijnders, Tom D.Y., Schinkel, Michiel, Schuurman, Alex R., Sikkens, Jonne J., Slim, Marleen A., Straten van der, Karlijn, Smulders, Yvo M., Vlaar, Alexander P.J., Vught van, Lonneke A., Wiersinga, W. Joost

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Indoleamine 2,3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19 von Guo, Lihui, Schurink, Bernadette, Roos, Eva, Nossent, Esther J, Duitman, Jan Willem, Vlaar, Alexander PJ, Valk, Paul, Vaz, Frédéric M, Yeh, Syun‐Ru, Geeraerts, Zachary, Dijkhuis, Annemiek, Vught, Lonneke, Bugiani, Marianna, Lutter, René

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Correlation between Serum Biomarkers and Lung Ultrasound in COVID-19: An Observational Study von Mousa, Amne, Blok, Siebe G, Karssen, Dian, Aman, Jurjan, Annema, Jouke T, Bogaard, Harm Jan, Bonta, Peter I, Haaksma, Mark E, Heldeweg, Micah L A, Lieveld, Arthur W E, Nanayakkara, Prabath, Nossent, Esther J, Smit, Jasper M, Smit, Marry R, Vlaar, Alexander P J, Schultz, Marcus J, Bos, Lieuwe D J, Paulus, Frederique, Tuinman, Pieter R, Amsterdam Umc Covid-Biobank Investigators

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Intramuscular adipose tissue at level Th12 is associated with survival in COVID‐19 von Viddeleer, Alain R., Raaphorst, Joost, Min, Minoesch, Beenen, Ludo F.M., Scheerder, Maeke J., Vlaar, Alexander P.J., Beudel, Martijn, Hemke, Robert, Bruin, Sanne, Schuurmans, Alex, Koning, Rutger, Agtmael, Michiel, Algera, Anne Geke, Baarle, Frank, Bax, Diane, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, Brabander, Justin, Bree, Godelieve, Bugiani, Marianna, Bulle, Esther, Chouchane, Osoul, Cloherty, Alex, Dongelmans, Dave A., Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geerts, Bart, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P., Hafkamp, Florianne, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M., Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W., Jong, Menno D., Mourik, Niels, Nossent, Esther J., Nellen, Jeaninne, Paulus, Frederique, Reijnders, Tom, Peters, Edgar, Poll, Tom, Preckel, Bennedikt, Prins, Jan M., Raasveld, Jorinde, Schinkel, Michiel, Schultz, Marcus J., Sigaloff, Kim, Smit, Marry, Stijnis, Cornelis S., Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa, Valk, Marc, Veelo, Denise, Vries, Heder, Vugt, Michèle, Wouters, Dorien, Zwinderman, A. H (Koos), Brouwer, Matthijs C., Wiersinga, W. Joost, Vlaar, Alexander P.J., Beek, Diederik

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Inflammatory biomarkers at hospital discharge are associated with readmission and death in patients hospitalized for COVID-19 von Slim, Marleen A., Appelman, Brent, Müller, Marcella C. A., Brouwer, Matthijs C., Vlaar, Alexander P. J., Wiersinga, W. Joost, van Vught, Lonneke A.

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Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes: data from the COVID-PREDICT cohort study in The Nethe... von Meijer, Rick I., Hoekstra, Trynke, van den Oever, Niels C. Gritters, Simsek, Suat, van den Bergh, Joop P., Douma, Renée A., Reidinga, Auke C., Moeniralam, Hazra S., Dormans, Tom, Smits, Mark M.

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Lipoprotein(a), venous thromboembolism and COVID-19: A pilot study von Nurmohamed, Nick S., Collard, Didier, Reeskamp, Laurens F., Kaiser, Yannick, Kroon, Jeffrey, Tromp, Tycho R., van den Born, Bert-Jan H., Coppens, Michiel, Vlaar, Alexander P.J., Beudel, Martijn, van de Beek, Diederik, van Es, Nick, Moriarty, Patrick M., Tsimikas, Sotirios, Stroes, Erik S.G.

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Sex steroid hormones are associated with mortality in COVID-19 patients: Level of sex hormones in severe COVID-19 von van Zeggeren, Ingeborg E., Boelen, Anita, van de Beek, Diederik, Heijboer, Annemieke C., Vlaar, Alexander P.J., Brouwer, Matthijs C.

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Dysregulation of cardiac endothelial lncRNA H19 in COVID19 patients induces endothelial dysfunction, which impairs cardiomyocyte function von Juni, Rio, Phelp, Philippa, Bink, Diewertje, Espinoza-Gonzales, Pedro, van Bergen, Anke, Kuster, Diederik, van der Velden, Jolanda, Krijnen, Paul, Niessen, Hans, Boon, Reinier

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Head-to-head validation of six immunoassays for SARS-CoV-2 in hospitalized patients von Zonneveld, Rens, Jurriaans, Suzanne, van Gool, Tom, Hofstra, Jorrit J., Hekker, Thecla A.M., Defoer, Pien, Broekhuizen-van Haaften, Patricia E., Wentink-Bonnema, Ellen M., Boonkamp, Lynn, Teunissen, Charlotte E., Heijboer, Annemieke C., Martens, Frans, de Bree, Godelieve, van Vugt, Michele, van Houdt, Robin, Schinkel, Janke, de Jong, Menno D., van Agtmael, M., Algera, A.G., van Baarle, F., Bax, D., Beudel, M., Bogaard, H.J., Bomers, M., Bos, L., Botta, M., de Brabander, J., Brouwer, M.C., de Bruin, S., Bugiani, M., Bulle, E., Chouchane, O., Cloherty, A., Elbers, P., Fleuren, L., Geerlings, S., Geerts, B., Geijtenbeek, T., Girbes, A., Goorhuis, A., Grobusch, M.P., Hafkamp, F., Hagens, L., Hamann, J., Harris, V., Hemke, R., Hermans, S.M., Heunks, L., Hollmann, M.W., Horn, J., Hovius, J.W., Koning, R., van Mourik, N., Nellen, J., Paulus, F., Peters, E., van der Poll, T., Preckel, B., Prins, J.M., Raasveld, J., Reijnders, T., Schinkel, M., Schultz, M.J., Schuurman, A., Sigaloff, K., Smit, M., Stijnis, C.S., Stilma, W., Thoral, P., Tsonas, A., van der Valk, M., Veelo, D., Vlaar, A.P.J., de Vries, H., Wiersinga, W.J., Wouters, D., Zwinderman, A.H., van de Beek, D.

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Cross-reactive antibodies after SARS-CoV-2 infection and vaccination von Grobben, Marloes, van der Straten, Karlijn, Brouwer, Philip Jm, Brinkkemper, Mitch, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Appelman, Brent, Lavell, Ah Ayesha, van Vught, Lonneke A, Burger, Judith A, Poniman, Meliawati, Oomen, Melissa, Eggink, Dirk, Bijl, Tom Pl, van Willigen, Hugo Dg, Wynberg, Elke, Verkaik, Bas J, Figaroa, Orlane Ja, de Vries, Peter J, Boertien, Tessel M, Bomers, Marije K, Sikkens, Jonne J, Le Grand, Roger, de Jong, Menno D, Prins, Maria, Chung, Amy W, de Bree, Godelieve J, Sanders, Rogier W, van Gils, Marit J

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