Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma von Christodoulou, Eirini, Rashid, Mamunur, Pacini, Clare, Droop, Alastair, Robertson, Holly, Groningen, Tim van, Teunisse, Amina F. A. S., Iorio, Francesco, Jochemsen, Aart G., Adams, David J., Doorn, Remco van

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MDMX Regulates Transcriptional Activity of p53 and FOXO Proteins to Stimulate Proliferation of Melanoma Cells von Heijkants, Renier C, Teunisse, Amina F. A. S, de Jong, Danielle, Glinkina, Kseniya, Mei, Hailiang, Kielbasa, Szymon M, Szuhai, Karoly, Jochemsen, Aart G

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Novel Treatments of Uveal Melanoma Identified with a Synthetic Lethal CRISPR/Cas9 Screen von Glinkina, Kseniya, Groenewoud, Arwin, Teunisse, Amina F A S, Snaar-Jagalska, B Ewa, Jochemsen, Aart G

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Alternate Splicing of the p53 Inhibitor HDMX Offers a Superior Prognostic Biomarker than p53 Mutation in Human Cancer von LENOS, Kristiaan, GRAWENDA, Anna M, TAUBERT, Helge, CLETON-JANSEN, Anne-Marie, BOND, Gareth L, JOCHEMSEN, Aart G, LODDER, Kirsten, KUIJJER, Marieke L, TEUNISSE, Amina F. A. S, REPAPI, Emmanouela, GROCHOLA, Lukasz F, BARTEL, Frank, HOGENDOORN, Pancras C. W, WUERL, Peter

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Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma von Dogrusöz, Mehmet, Ruschel Trasel, Andrea, Cao, Jinfeng, Ҫolak, Selҫuk, van Pelt, Sake I, Kroes, Wilma G M, Teunisse, Amina F A S, Alsafadi, Samar, van Duinen, Sjoerd G, Luyten, Gregorius P M, van der Velden, Pieter A, Amaro, Adriana, Pfeffer, Ulrich, Jochemsen, Aart G, Jager, Martine J

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Phosphorylation of Hdmx Mediates Its Hdm2- and ATM-Dependent Degradation in Response to DNA Damage von Pereg, Yaron, Shkedy, Dganit, de Graaf, Petra, Meulmeester, Erik, Edelson-Averbukh, Marina, Salek, Mogjiborahman, Biton, Sharon, Amina F. A. S. Teunisse, Lehmann, Wolf D., Jochemsen, Aart G., Shiloh, Yosef, Elledge, Stephen J.

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Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy von Beyranvand Nejad, Elham, Labrie, Camilla, Abdulrahman, Ziena, van Elsas, Marit J, Rademaker, Eva, Kleinovink, Jan Willem, van der Sluis, Tetje C, van Duikeren, Suzanne, Teunisse, Amina F A.S, Jochemsen, Aart G, Oosting, Jan, de Miranda, Noel F C C, Van Hall, Thorbald, Arens, Ramon, van der Burg, Sjoerd H

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Targeting epigenetic regulation and post-translational modification with 5-Aza-2’ deoxycytidine and SUMO E1 inhibition augments T-cell receptor therapy von Kroonen, Jessie S, Wouters, Anne K, de Graaf, Ilona J, Remst, Dennis F G, Kumar, Sumit, Wachsmann, Tassilo L A, Teunisse, Amina F A S, Roelands, Jessica P, de Miranda, Noel F C C, Griffioen, Marieke, Heemskerk, Mirjam H M, Vertegaal, Alfred C O

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Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma von Glinkina, Kseniya, Nemati, Fariba, Teunisse, Amina F A S, Gelmi, Maria Chiara, Etienne, Vesnie, Kuipers, Muriel J, Alsafadi, Samar, Jager, Martine J, Decaudin, Didier, Jochemsen, Aart G

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Modeling of human uveal melanoma in zebrafish xenograft embryos von van der Ent, Wietske, Burrello, Claudia, Teunisse, Amina F A S, Ksander, Bruce R, van der Velden, Pieter A, Jager, Martine J, Jochemsen, Aart G, Snaar-Jagalska, B Ewa

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Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice von Boesten, Lianne S.M, Zadelaar, A. Susanne M, van Nieuwkoop, Anita, Hu, Lihui, Teunisse, Amina F.A.S, Jochemsen, Aart G, Evers, Bastiaan, van de Water, Bob, Gijbels, Marion J.J, van Vlijmen, Bart J.M, Havekes, Louis M, de Winther, Menno P.J

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Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53 von van der Ent, Wietske, Jochemsen, Aart G, Teunisse, Amina FAS, Krens, SF Gabriel, Szuhai, Karoly, Spaink, Herman P, Hogendoorn, Pancras CW, Snaar-Jagalska, B Ewa

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Wild-type p53 inhibits pro-invasive properties of TGF-β3 in breast cancer, in part through regulation of EPHB2, a new TGF-β target gene von Lam, Suzanne, Wiercinska, Eliza, Teunisse, Amina F. A. S., Lodder, Kirsten, ten Dijke, Peter, Jochemsen, Aart G.

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Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer von Grawenda, Anna M, Møller, Elen K, Lam, Suzanne, Repapi, Emmanouela, Teunisse, Amina F A S, Alnæs, Grethe I G, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Goding, Colin R, Jochemsen, Aart G, Edvardsen, Hege, Bond, Gareth L

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Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts von Lenos, Kristiaan, de Lange, Job, Teunisse, Amina F A S, Lodder, Kirsten, Verlaan-de Vries, Matty, Wiercinska, Eliza, van der Burg, Marja J M, Szuhai, Karoly, Jochemsen, Aart G

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Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target von Cao, Jinfeng, Pontes, Kelly CS, Heijkants, Renier C, Brouwer, Niels J, Groenewoud, Arwin, Jordanova, Ekaterina S, Marinkovic, Marina, van Duinen, Sjoerd, Teunisse, Amina FAS, Verdijk, Robert M, Snaar‐Jagalska, Ewa, Jochemsen, Aart G, Jager, Martine J

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MDM4 is a rational target for treating breast cancers with mutant p53 von Miranda, Panimaya Jeffreena, Buckley, Daniel, Raghu, Dinesh, Pang, Jia‐Min B, Takano, Elena A, Vijayakumaran, Reshma, Teunisse, Amina FAS, Posner, Atara, Procter, Tahlia, Herold, Marco J, Gamell, Cristina, Marine, Jean‐Christophe, Fox, Stephen B, Jochemsen, Aart, Haupt, Sue, Haupt, Ygal

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Loss of HAUSP-Mediated Deubiquitination Contributes to DNA Damage-Induced Destabilization of Hdmx and Hdm2 von Meulmeester, Erik, Maurice, Madelon M., Boutell, Chris, Teunisse, Amina F.A.S., Ovaa, Huib, Abraham, Tsion E., Dirks, Roeland W., Jochemsen, Aart G.

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Wild-type p53 inhibits pro-invasive properties of TGF- beta 3 in breast cancer, in part through regulation of EPHB2, a new TGF- beta target gene von Lam, Suzanne, Wiercinska, Eliza, Teunisse, Amina FAS, Lodder, Kirsten, ten Dijke, Peter, Jochemsen, Aart G

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Wild-type p53 inhibits pro-invasive properties of TGF-[beta]3 in breast cancer, in part through regulation of EPHB2, a new TGF-[beta] target gene von Lam, Suzanne, Wiercinska, Eliza, Teunisse, Amina F, A, S, Lodder, Kirsten, Ten Dijke, Peter, Jochemsen, Aart G

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