Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction von Jiang, Changtao, Xie, Cen, Lv, Ying, Li, Jing, Krausz, Kristopher W., Shi, Jingmin, Brocker, Chad N., Desai, Dhimant, Amin, Shantu G., Bisson, William H., Liu, Yulan, Gavrilova, Oksana, Patterson, Andrew D., Gonzalez, Frank J.

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Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles von Hubbard, Troy D., Murray, Iain A., Bisson, William H., Lahoti, Tejas S., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

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Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity von Dong, Fangcong, Hao, Fuhua, Murray, Iain A., Smith, Philip B., Koo, Imhoi, Tindall, Alyssa M., Kris-Etherton, Penny M., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

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Genetic and Pharmacological Analysis Identifies a Physiological Role for the AHR in Epidermal Differentiation von van den Bogaard, Ellen H., Podolsky, Michael A., Smits, Jos P., Cui, Xiao, John, Christian, Gowda, Krishne, Desai, Dhimant, Amin, Shantu G., Schalkwijk, Joost, Perdew, Gary H., Glick, Adam B.

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KS18, a Mcl-1 inhibitor, improves the effectiveness of bortezomib and overcomes resistance in refractory multiple myeloma by triggering intrinsic apoptosis von Al-Odat, Omar S, Elbezanti, Weam Othman, Gowda, Krishne, Srivastava, Sandeep K, Amin, Shantu G, Jonnalagadda, Subash C, Budak-Alpdogan, Tulin, Pandey, Manoj K

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Editor's Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin von Smith, Kayla J, Boyer, Jacob A, Muku, Gulsum E, Murray, Iain A, Gowda, Krishne, Desai, Dhimant, Amin, Shantu G, Glick, Adam B, Perdew, Gary H

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Ah receptor antagonism represses head and neck tumor cell aggressive phenotype von DiNatale, Brett C, Smith, Kayla, John, Kaarthik, Krishnegowda, Gowdahalli, Amin, Shantu G, Perdew, Gary H

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Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases von Kale, Vijay Pralhad, Hengst, Jeremy A, Sharma, Arati K, Golla, Upendarrao, Dovat, Sinisa, Amin, Shantu G, Yun, Jong K, Desai, Dhimant H

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Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways von Pandey, Manoj K, Kale, Vijay P, Song, Chunhua, Sung, Shen-shu, Sharma, Arun K, Talamo, Giampaolo, Dovat, Sinisa, Amin, Shantu G

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Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer von Morad, Samy A.F., Davis, Traci S., MacDougall, Matthew R., Tan, Su-Fern, Feith, David J., Desai, Dhimant H., Amin, Shantu G., Kester, Mark, Loughran, Thomas P., Cabot, Myles C.

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Glycine‐β‐muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice von Jiang, Jie, Ma, Yuandi, Liu, Yameng, Lu, Dasheng, Gao, Xiaoxia, Krausz, Kristopher W., Desai, Dhimant, Amin, Shantu G., Patterson, Andrew D., Gonzalez, Frank J., Xie, Cen

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Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice von Zhu, Xiaoyang, Liu, Qing, Patterson, Andrew D., Sharma, Arun K., Amin, Shantu G., Cohen, Samuel M., Gonzalez, Frank J., Peters, Jeffrey M.

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Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease von Jiang, Changtao, Xie, Cen, Li, Fei, Zhang, Limin, Nichols, Robert G, Krausz, Kristopher W, Cai, Jingwei, Qi, Yunpeng, Fang, Zhong-Ze, Takahashi, Shogo, Tanaka, Naoki, Desai, Dhimant, Amin, Shantu G, Albert, Istvan, Patterson, Andrew D, Gonzalez, Frank J

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Targeting ion channels for cancer therapy by repurposing the approved drugs von Kale, Vijay Pralhad, Amin, Shantu G., Pandey, Manoj K.

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A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion von Kale, Vijay Pralhad, Hengst, Jeremy A, Desai, Dhimant H, Dick, Taryn E, Choe, Katherine N, Colledge, Ashley L, Takahashi, Yoshinori, Sung, Shen-Shu, Amin, Shantu G, Yun, Jong K

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Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites von Patel, Dhwani, Murray, Iain A, Dong, Fangcong, Annalora, Andrew J, Gowda, Krishne, Coslo, Denise M, Krzeminski, Jacek, Koo, Imhoi, Hao, Fuhua, Amin, Shantu G, Marcus, Craig B, Patterson, Andrew D, Perdew, Gary H

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Aryl Hydrocarbon Receptor Activation Coordinates Mouse Small Intestinal Epithelial Cell Programming von Zhou, Xiaoliang, Chakraborty, Debopriya, Murray, Iain A., Coslo, Denise, Kehs, Zoe, Vijay, Anitha, Ton, Carolyn, Desai, Dhimant, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

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Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia von Song, Chunhua, Gowda, Chandrika, Pan, Xiaokang, Ding, Yali, Tong, Yongqing, Tan, Bi-Hua, Wang, Haijun, Muthusami, Sunil, Ge, Zheng, Sachdev, Mansi, Amin, Shantu G., Desai, Dhimant, Gowda, Krishne, Gowda, Raghavendra, Robertson, Gavin P., Schjerven, Hilde, Muschen, Markus, Payne, Kimberly J., Dovat, Sinisa

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Differential regulation of Th17 and T regulatory cell differentiation by aryl hydrocarbon receptor dependent xenobiotic response element dependent and independent pathways von Mohinta, Sonia, Kannan, Arun K, Gowda, Krishne, Amin, Shantu G, Perdew, Gary H, August, Avery

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Complex chemical signals dictate Ah receptor activation through the gut–lung axis von Dong, Fangcong, Murray, Iain A., Annalora, Andrew, Coslo, Denise M., Desai, Dhimant, Gowda, Krishne, Yang, Jian, Wang, Dingbowen, Koo, Imhoi, Hao, Fuhua, Amin, Shantu G., Patterson, Andrew D., Marcus, Craig, Perdew, Gary H.

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