D3R Grand Challenge 3: blind prediction of protein–ligand poses and affinity rankings von Gaieb, Zied, Parks, Conor D., Chiu, Michael, Yang, Huanwang, Shao, Chenghua, Walters, W. Patrick, Lambert, Millard H., Nevins, Neysa, Bembenek, Scott D., Ameriks, Michael K., Mirzadegan, Tara, Burley, Stephen K., Amaro, Rommie E., Gilson, Michael K.

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Skeletal Editing Approach to Bridge-Functionalized Bicyclo[1.1.1]pentanes from Azabicyclo[2.1.1]hexanes von Wright, Brandon A., Matviitsuk, Anastassia, Black, Michael J., García-Reynaga, Pablo, Hanna, Luke E., Herrmann, Aaron T., Ameriks, Michael K., Sarpong, Richmond, Lebold, Terry P.

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D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies von Parks, Conor D., Gaieb, Zied, Chiu, Michael, Yang, Huanwang, Shao, Chenghua, Walters, W. Patrick, Jansen, Johanna M., McGaughey, Georgia, Lewis, Richard A., Bembenek, Scott D., Ameriks, Michael K., Mirzadegan, Tara, Burley, Stephen K., Amaro, Rommie E., Gilson, Michael K.

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Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8 von Maher, Michael P, Wu, Nyantsz, Ravula, Suchitra, Ameriks, Michael K, Savall, Brad M, Liu, Changlu, Lord, Brian, Wyatt, Ryan M, Matta, Jose A, Dugovic, Christine, Yun, Sujin, Ver Donck, Luc, Steckler, Thomas, Wickenden, Alan D, Carruthers, Nicholas I, Lovenberg, Timothy W

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Correction: Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism von Punjajom, Kunlayanee, Sinclair, Paul P, Saha, Ishika, Seierstad, Mark, Ameriks, Michael K, García-Reynaga, Pablo, Lebold, Terry P, Sarpong, Richmond

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Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism von Punjajom, Kunlayanee, Sinclair, Paul P, Saha, Ishika, Seierstad, Mark, Ameriks, Michael K, García-Reynaga, Pablo, Lebold, Terry P, Sarpong, Richmond

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Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Poten... von Wyatt, Ryan M., Fraser, Ian, Welty, Natalie, Lord, Brian, Wennerholm, Michelle, Sutton, Steven, Ameriks, Michael K., Dugovic, Christine, Yun, Sujin, White, Allison, Nguyen, Leslie, Koudriakova, Tatiana, Tian, Gaochao, Suarez, Javier, Szewczuk, Lawrence, Bonnette, William, Ahn, Kay, Ghosh, Brahma, Flores, Christopher M., Connolly, Peter J., Zhu, Bin, Macielag, Mark J., Brandt, Michael R., Chevalier, Kristen, Zhang, Sui-Po, Lovenberg, Timothy, Bonaventure, Pascal

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Development of a Flexible Strategy towards FR900482 and the Mitomycins von Trost, Barry M., O'Boyle, Brendan M., Torres, Wildeliz, Ameriks, Michael K.

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A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334 von Lord, Brian, Ameriks, Michael K., Wang, Qi, Fourgeaud, Lawrence, Vliegen, Maarten, Verluyten, Willy, Haspeslagh, Pieter, Carruthers, Nicholas I., Lovenberg, Timothy W., Bonaventure, Pascal, Letavic, Michael A., Bhattacharya, Anindya

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Preclinical characterization of substituted 6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one P2X7 receptor antagonists von Ameriks, Michael K., Ao, Hong, Carruthers, Nicholas I., Lord, Brian, Ravula, Suchitra, Rech, Jason C., Savall, Brad M., Wall, Jessica L., Wang, Qi, Bhattacharya, Anindya, Letavic, Michael A.

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Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse von Eckert, William A., Wiener, John J.M., Cai, Hui, Ameriks, Michael K., Zhu, Jian, Ngo, Karen, Nguyen, Steven, Fung-Leung, Wai-Ping, Thurmond, Robin L., Grice, Cheryl, Edwards, James P., Chaplan, Sandra R., Karlsson, Lars, Sun, Siquan

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Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists von Rudolph, Dale A., Alcazar, Jesus, Ameriks, Michael K., Anton, Ana Belen, Ao, Hong, Bonaventure, Pascal, Carruthers, Nicholas I., Chrovian, Christa C., De Angelis, Meri, Lord, Brian, Rech, Jason C., Wang, Qi, Bhattacharya, Anindya, Andres, Jose Ignacio, Letavic, Michael A.

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Discovery of Imidazo[1,2‑a]pyrazines and Pyrazolo­[1,5‑c]­pyrimidines as TARP γ‑8 Selective AMPAR Negative Modulators von Savall, Brad M, Wu, Dongpei, Swanson, Devin M, Seierstad, Mark, Wu, Nyantsz, Vives Martinez, Jorge, García Olmos, Beatriz, Lord, Brian, Coe, Kevin, Koudriakova, Tatiana, Lovenberg, Timothy W, Carruthers, Nicholas I, Maher, Michael P, Ameriks, Michael K

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Lead Optimization of 5‑Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ‑8 von Ravula, Suchitra, Savall, Brad M, Wu, Nyantsz, Lord, Brian, Coe, Kevin, Wang, Kai, Seierstad, Mark, Swanson, Devin M, Ziff, Jeannie, Nguyen, Minh, Leung, Perry, Rynberg, Ray, La, David, Pippel, Daniel J, Koudriakova, Tatiana, Lovenberg, Timothy W, Carruthers, Nicholas I, Maher, Michael P, Ameriks, Michael K

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Pd-Catalyzed Carbonylative Lactamization:  A Novel Synthetic Approach to FR900482 von Trost, Barry M, Ameriks, Michael K

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Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors von Ameriks, Michael K., Bembenek, Scott D., Burdett, Matthew T., Choong, Ingrid C., Edwards, James P., Gebauer, Damara, Gu, Yin, Karlsson, Lars, Purkey, Hans E., Staker, Bart L., Sun, Siquan, Thurmond, Robin L., Zhu, Jian

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Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements von Ameriks, Michael K., Axe, Frank U., Bembenek, Scott D., Edwards, James P., Gu, Yin, Karlsson, Lars, Randal, Mike, Sun, Siquan, Thurmond, Robin L., Zhu, Jian

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Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: Optimization of cellular potency von Ameriks, Michael K., Cai, Hui, Edwards, James P., Gebauer, Damara, Gleason, Elizabeth, Gu, Yin, Karlsson, Lars, Nguyen, Steven, Sun, Siquan, Thurmond, Robin L., Zhu, Jian

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Skeletal Editing Approach to Bridge-Functionalized Bicyclo1.1.1pentanes from Azabicyclo2.1.1hexanes von Wright, Brandon A, Matviitsuk, Anastassia, Black, Michael J, García-Reynaga, Pablo, Hanna, Luke E, Herrmann, Aaron T, Ameriks, Michael K, Sarpong, Richmond, Lebold, Terry P

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Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: Part 1 von Lee-Dutra, Alice, Wiener, Danielle K., Arienti, Kristen L., Liu, Jing, Mani, Neelakandha, Ameriks, Michael K., Axe, Frank U., Gebauer, Damara, Desai, Pragnya J., Nguyen, Steven, Randal, Mike, Thurmond, Robin L., Sun, Siquan, Karlsson, Lars, Edwards, James P., Jones, Todd K., Grice, Cheryl A.

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