A proteome-wide atlas of lysine-reactive chemistry von Abbasov, Mikail E., Kavanagh, Madeline E., Ichu, Taka-Aki, Lazear, Michael R., Tao, Yongfeng, Crowley, Vincent M., am Ende, Christopher W., Hacker, Stephan M., Ho, Jordan, Dix, Melissa M., Suciu, Radu, Hayward, Matthew M., Kiessling, Laura L., Cravatt, Benjamin F.

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Divergent Synthesis of Monosubstituted and Unsymmetrical 3,6‐Disubstituted Tetrazines from Carboxylic Ester Precursors von Xie, Yixin, Fang, Yinzhi, Huang, Zhen, Tallon, Amanda M., am Ende, Christopher W., Fox, Joseph M.

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Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells von Offensperger, Fabian, Tin, Gary, Duran-Frigola, Miquel, Hahn, Elisa, Dobner, Sarah, Ende, Christopher W Am, Strohbach, Joseph W, Rukavina, Andrea, Brennsteiner, Vincenth, Ogilvie, Kevin, Marella, Nara, Kladnik, Katharina, Ciuffa, Rodolfo, Majmudar, Jaimeen D, Field, S Denise, Bensimon, Ariel, Ferrari, Luca, Ferrada, Evandro, Ng, Amanda, Zhang, Zhechun, Degliesposti, Gianluca, Boeszoermenyi, Andras, Martens, Sascha, Stanton, Robert, Müller, André C, Hannich, J Thomas, Hepworth, David, Superti-Furga, Giulio, Kubicek, Stefan, Schenone, Monica, Winter, Georg E

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Dual-Reactivity trans-Cyclooctenol Probes for Sulfenylation in Live Cells Enable Temporal Control via Bioorthogonal Quenching von Scinto, Samuel L, Ekanayake, Oshini, Seneviratne, Uthpala, Pigga, Jessica E, Boyd, Samantha J, Taylor, Michael T, Liu, Jun, am Ende, Christopher W, Rozovsky, Sharon, Fox, Joseph M

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Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase von Butler, Christopher R., Beck, Elizabeth M., Harris, Anthony, Huang, Zhen, McAllister, Laura A., am Ende, Christopher W., Fennell, Kimberly, Foley, Timothy L., Fonseca, Kari, Hawrylik, Steven J., Johnson, Douglas S., Knafels, John D., Mente, Scot, Noell, G. Stephen, Pandit, Jayvardhan, Phillips, Tracy B., Piro, Justin R., Rogers, Bruce N., Samad, Tarek A., Wang, Jane, Wan, Shuangyi, Brodney, Michael A.

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A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis von Luckner, Sylvia R., Liu, Nina, am Ende, Christopher W., Tonge, Peter J., Kisker, Caroline

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Photochemical syntheses, transformations, and bioorthogonal chemistry of trans -cycloheptene and sila trans -cycloheptene Ag(i) complexes von Fang, Yinzhi, Zhang, Han, Huang, Zhen, Scinto, Samuel L, Yang, Jeffrey C, Am Ende, Christopher W, Dmitrenko, Olga, Johnson, Douglas S, Fox, Joseph M

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Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors von Zuhl, Andrea M., Nolan, Charles E., Brodney, Michael A., Niessen, Sherry, Atchison, Kevin, Houle, Christopher, Karanian, David A., Ambroise, Claude, Brulet, Jeffrey W., Beck, Elizabeth M., Doran, Shawn D., O’Neill, Brian T., am Ende, Christopher W., Chang, Cheng, Geoghegan, Kieran F., West, Graham M., Judkins, Joshua C., Hou, Xinjun, Riddell, David R., Johnson, Douglas S.

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Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum von Esquejo, Ryan M., Roqueta-Rivera, Manuel, Shao, Wei, Phelan, Peter E., Seneviratne, Uthpala, am Ende, Christopher W., Hershberger, Paul M., Machamer, Carolyn E., Espenshade, Peter J., Osborne, Timothy F.

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Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10–2474 von Huang, Zhen, Ogasawara, Daisuke, Seneviratne, Uthpala I, Cognetta, Armand B, am Ende, Christopher W, Nason, Deane M, Lapham, Kimberly, Litchfield, John, Johnson, Douglas S, Cravatt, Benjamin F

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Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies von Conrad, Karen S., Cheng, Ting-Wen, Ysselstein, Daniel, Heybrock, Saskia, Hoth, Lise R., Chrunyk, Boris A., am Ende, Christopher W., Krainc, Dimitri, Schwake, Michael, Saftig, Paul, Liu, Shenping, Qiu, Xiayang, Ehlers, Michael D.

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Late-stage difluoromethylation: concepts, developments and perspective von Sap, Jeroen B. I, Meyer, Claudio F, Straathof, Natan J. W, Iwumene, Ndidi, am Ende, Christopher W, Trabanco, Andrés A, Gouverneur, Véronique

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Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert‐Butyl Isostere von Mukherjee, Paramita, Pettersson, Martin, Dutra, Jason K., Xie, Longfei, am Ende, Christopher W.

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Catalytic Activation of Bioorthogonal Chemistry with Light (CABL) Enables Rapid, Spatiotemporally Controlled Labeling and No-Wash, Subcellular 3D-Patterning in Live Cells Using Lon... von Jemas, Andrew, Xie, Yixin, Pigga, Jessica E, Caplan, Jeffrey L, am Ende, Christopher W, Fox, Joseph M

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Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides von Zhou, Hua, Mukherjee, Paramita, Liu, Rongqiang, Evrard, Edelweiss, Wang, Dianpeng, Humphrey, John M, Butler, Todd W, Hoth, Lise R, Sperry, Jeffrey B, Sakata, Sylvie K, Helal, Christopher J, am Ende, Christopher W

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Protocol for clickable photoaffinity labeling and quantitative chemical proteomics von Lee, Wankyu, Huang, Zhen, am Ende, Christopher W., Seneviratne, Uthpala

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Sulfonamide Synthesis via Calcium Triflimide Activation of Sulfonyl Fluorides von Mukherjee, Paramita, Woroch, Cristian P, Cleary, Leah, Rusznak, Mark, Franzese, Ryan W, Reese, Matthew R, Tucker, Joseph W, Humphrey, John M, Etuk, Sarah M, Kwan, Sabrina C, am Ende, Christopher W, Ball, Nicholas D

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Installation of Minimal Tetrazines through Silver-Mediated Liebeskind–Srogl Coupling with Arylboronic Acids von Lambert, William D, Fang, Yinzhi, Mahapatra, Subham, Huang, Zhen, am Ende, Christopher W, Fox, Joseph M

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Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging von Murrey, Heather E, Judkins, Joshua C, am Ende, Christopher W, Ballard, T. Eric, Fang, Yinzhi, Riccardi, Keith, Di, Li, Guilmette, Edward R, Schwartz, Joel W, Fox, Joseph M, Johnson, Douglas S

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Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be “Switched Off” via Bioorthogonal Chemistry Inside Live Cells von Tallon, Amanda M., Xu, Yingrong, West, Graham M., am Ende, Christopher W., Fox, Joseph M.

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