Anti‐tumour efficacy on glioma models of PHA‐848125, a multi‐kinase inhibitor able to cross the blood–brain barrier von Albanese, C, Alzani, R, Amboldi, N, Degrassi, A, Festuccia, C, Fiorentini, F, Gravina, GL, Mercurio, C, Pastori, W, Brasca, MG, Pesenti, E, Galvani, A, Ciomei, M

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NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies von Ardini, E, Lombardi Borgia, A, Texido, G, Alzani, R, Avanzi, N, Amboldi, N, Cribioli, S, Mancini, L, Casero, D, Pastori, W, Montemartini, M, Montagnoli, A, Donati, D, Galvani, A, Isacchi, A, Ciomei, M

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31 N-Myc amplification sensitizes tumor cells to inhibition by Danusertib, an Aurora kinase inhibitor von Carpinelli, P, Ceruti, R, Alzani, R, Re, C, Ballinari, D, Cribioli, S, Russo, M, Degrassi, A, Texido, G, Ciomei, M, Pesenti, E, Montagnoli, A, Galvani, A

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization von Pevarello, Paolo, Brasca, Maria Gabriella, Orsini, Paolo, Traquandi, Gabriella, Longo, Antonio, Nesi, Marcella, Orzi, Fabrizio, Piutti, Claudia, Sansonna, Pietro, Varasi, Mario, Cameron, Alexander, Vulpetti, Anna, Roletto, Fulvia, Alzani, Rachele, Ciomei, Marina, Albanese, Clara, Pastori, Wilma, Marsiglio, Aurelio, Pesenti, Enrico, Fiorentini, Francesco, Bischoff, Jim R, Mercurio, Ciro

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388 - NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies von Ardini, E., Lombardi Borgia, A., Texido, G., Alzani, R., Avanzi, N., Amboldi, N., Cribioli, S., Mancini, L., Casero, D., Pastori, W., Montemartini, M., Montagnoli, A., Donati, D., Galvani, A., Isacchi, A., Ciomei, M.

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Suramin induces deoligomerization of human tumor necrosis factor alpha von ALZANI, R, CORTI, A, GRAZIOLI, L, COZZI, E, GHEZZI, P, MARCUCCI, F

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294 POSTER Biological characterization of the dual CDK2/TRKA inhibitor PHA-848125 von Alzani, R, Albanese, C, Locatelli, G, Pastori, W, Amboldi, N, Croci, W, Fiorentini, F, Roletto, F, DePonti, C, Mercurio, C

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Mechanism of suramin-induced deoligomerization of tumor necrosis factor .alpha von Alzani, R, Cozzi, E, Corti, A, Temponi, M, Trizio, D, Gigli, M, Rizzo, V

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Phase l study of the oral CDK-TRKA inhibitor PHA-848125 administered with prolonged schedules of administration von Cresta, S., Sessa, C., Del Conte, G., Locatelli, A., Gallerani, E., Fiorentini, F., Scaburri, A., Pacciarini, M. A., Alzani, R., Gianni, L.

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Chlorpromazine inhibits tumour necrosis factor synthesis and cytotoxicity in vitro von Zinetti, M, Galli, G, Demitri, M T, Fantuzzi, G, Minto, M, Ghezzi, P, Alzani, R, Cozzi, E, Fratelli, M

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3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization von Pevarello, Paolo, Brasca, Maria Gabriella, Orsini, Paolo, Traquandi, Gabriella, Longo, Antonio, Nesi, Marcella, Orzi, Fabrizio, Piutti, Claudia, Sansonna, Pietro, Varasi, Mario, Cameron, Alexander, Vulpetti, Anna, Roletto, Fulvia, Alzani, Rachele, Ciomei, Marina, Albanese, Clara, Pastori, Wilma, Marsiglio, Aurelio, Pesenti, Enrico, Fiorentini, Francesco, Bischoff, Jim R, Mercurio, Ciro

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Anti-human tumor antibodies induced in mice and rabbits by "internal image" anti-idiotypic monoclonal immunoglobulins von Viale, G, Grassi, F, Pelagi, M, Alzani, R, Menard, S, Miotti, S, Buffa, R, Gini, A, Siccardi, AG

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Monoclonal antibodies against NIH 3T3 cells transformed by human thyroid carcinoma DNA von ALZANI, R, PIEROTTI, M. A, FUSCO, A, GRIECO, M, DELLA PORTA, G, COLNAGHI, M. I, MENARD, S, CANEVARI, S, FERTONANI, M. L, BALLINARI, D, TRAVERSARI, C, DELLA TORRE, G, RADICE, P, PILOTTI, S

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Detection of mycoplasma contamination through modulation (stimulation or inhibition) of thymidine incorporation by unstimulated mouse spleen cells von Alzani, Rachele, Rossi, Rosaria, Cozzi, Elena, Trizio, Domenico, Marcucci, Fabrizio

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Inhibitory effect of suramin on receptor binding and cytotoxic activity of tumor necrosis factor α von Grazioli, Laura, Alzani, Rachele, Ciomei, Marina, Mariani, Mariangela, Restivo, Alessandra, Cozzi, Elena, Marcucci, Fabrizio

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Monoclonal antibodies against doxorubicin von Balsari, Andrea, Alzani, Rachele, Parrello, Daniele, Morelli, Daniele, Tagliabue, Elda, Gianni, Luca, Isetta, Anna Maria, Menard, Sylvie, Colnaghi, Maria Ines, Ghione, Mario

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Inhibitory effect of suramin on receptor binding and cytotoxic activity of tumor necrosis factor alpha von Grazioli, L, Alzani, R, Ciomei, M, Mariani, M, Restivo, A, Cozzi, E, Marcucci, F

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Monoclonal antibodies against NIH 3T3 cells transformed by human thyroid carcinoma DNA von Alzani, R., Della Torre, G., Traversari, C., Pierotti, M., Ménard, S., Della Porta, G., Colnaghi, M.I.

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