Dendritic Cells and Their Role in Immunotherapy von Gardner, Alycia, de Mingo Pulido, Alvaro, Ruffell, Brian

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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake von de Mingo Pulido, Álvaro, Hänggi, Kay, Celias, Daiana P., Gardner, Alycia, Li, Jie, Batista-Bittencourt, Bruna, Mohamed, Eslam, Trillo-Tinoco, Jimena, Osunmakinde, Olabisi, Peña, Reymi, Onimus, Alexis, Kaisho, Tsuneyasu, Kaufmann, Johanna, McEachern, Kristen, Soliman, Hatem, Luca, Vincent C., Rodriguez, Paulo C., Yu, Xiaoqing, Ruffell, Brian

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Dendritic Cells and Cancer Immunity von Gardner, Alycia, Ruffell, Brian

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Combating castration-resistant prostate cancer by co-targeting the epigenetic regulators EZH2 and HDAC von Schade, Amy E, Kuzmickas, Ryan, Rodriguez, Carrie L, Mattioli, Kaia, Enos, Miriam, Gardner, Alycia, Cichowski, Karen

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moDCs, Less Problems von Gardner, Alycia, Ruffell, Brian

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Reducing interferon'ce in stem cells von Gardner, Alycia, Ruffell, Brian

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TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer von de Mingo Pulido, Álvaro, Gardner, Alycia, Hiebler, Shandi, Soliman, Hatem, Rugo, Hope S., Krummel, Matthew F., Coussens, Lisa M., Ruffell, Brian

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Combating castration-resistant prostate cancer by co-targeting the epigenetic regulators EZH2 and HDAC von Amy E. Schade, Ryan Kuzmickas, Carrie L. Rodriguez, Kaia Mattioli, Miriam Enos, Alycia Gardner, Karen Cichowski

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DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer von Miller, Abigail L, Perurena, Naiara, Gardner, Alycia, Hinoue, Toshinori, Loi, Patrick, Laird, Peter W, Cichowski, Karen

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A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3, N 4 -ethenocytosine von Chaim, Isaac A., Gardner, Alycia, Wu, Jie, Iyama, Teruaki, Wilson, David M., Samson, Leona D.

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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity von Hänggi, Kay, Li, Jie, Gangadharan, Achintyan, Liu, Xiaoxian, Celias, Daiana P, Osunmakinde, Olabisi, Keske, Aysenur, Davis, Joshua, Ahmad, Faiz, Giron, Auriane, Anadon, Carmen M, Gardner, Alycia, DeNardo, David G, Shaw, Timothy I, Beg, Amer A, Yu, Xiaoqing, Ruffell, Brian

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AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution von Schade, Amy E., Perurena, Naiara, Yang, Yoona, Rodriguez, Carrie L., Krishnan, Anjana, Gardner, Alycia, Loi, Patrick, Xu, Yilin, Nguyen, Van T. M., Mastellone, G. M., Pilla, Natalie F., Watanabe, Marina, Ota, Keiichi, Davis, Rachel A., Mattioli, Kaia, Xiang, Dongxi, Zoeller, Jason J., Lin, Jia-Ren, Morganti, Stefania, Garrido-Castro, Ana C., Tolaney, Sara M., Li, Zhe, Barbie, David A., Sorger, Peter K., Helin, Kristian, Santagata, Sandro, Knott, Simon R. V., Cichowski, Karen

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Abstract 655: Necroptosis promotes tumor growth through IL1-alpha release and recruitment of immunosuppressive myeloid cells von Hänggi, Kay, Keske, Aysenur, Gardner, Alycia, Li, Jie, Osunmakinde, Olabisi, Celias, Daiana, Beg, Amer, Ruffell, Brian

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TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8+ T cell and XCR1+ dendritic cell spatial co-localization von Gardner, Alycia, de Mingo Pulido, Álvaro, Hänggi, Kay, Bazargan, Sarah, Onimus, Alexis, Kasprzak, Agnieszka, Conejo-Garcia, Jose R, Rejniak, Katarzyna A, Ruffell, Brian

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Abstract P1-13-06: Loss of emerging tumor and metastasis suppressor RasGAPs mediates therapeutic resistance in HER2+ breast cancer von Perurena, Naiara, Pilla, Natalie, Schade, Amy, Watanabe, Marina, Loi, Patrick, Rodriguez, Carrie L., Gardner, Alycia M., Cichowski, Karen

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A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine von Chaim, Isaac A, Gardner, Alycia, Wu, Jie, Iyama, Teruaki, Wilson, 3rd, David M, Samson, Leona D

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Fucosylation of HLA-DRB1 regulates CD4 + T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy von Lester, Daniel K, Burton, Chase, Gardner, Alycia, Innamarato, Patrick, Kodumudi, Krithika, Liu, Qian, Adhikari, Emma, Ming, Qianqian, Williamson, Daniel B, Frederick, Dennie T, Sharova, Tatyana, White, Michael G, Markowitz, Joseph, Cao, Biwei, Nguyen, Jonathan, Johnson, Joseph, Beatty, Matthew, Mockabee-Macias, Andrea, Mercurio, Matthew, Watson, Gregory, Chen, Pei-Ling, McCarthy, Susan, MoranSegura, Carlos, Messina, Jane, Thomas, Kerry L, Darville, Lancia, Izumi, Victoria, Koomen, John M, Pilon-Thomas, Shari A, Ruffell, Brian, Luca, Vincent C, Haltiwanger, Robert S, Wang, Xuefeng, Wargo, Jennifer A, Boland, Genevieve M, Lau, Eric K

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Antigen Directed Therapy Pre-Transplant Confers Superior Post-Transplant Survival Outcome Compared to Conventional Chemotherapy in Pediatric Patients with Relapsed and Refractory B... von Stiefel, Jessica, Flower, Allyson M., Botwinick, Marissa, Ford, Maegan, Foti, Alycia, Gandhi, Mital, Slovin, Justin, Smilow, Elana, Bowers, Ashley, Karpel, Hannah, Schwartz, Leya Y, Fraint, Ellen, Gennarini, Lisa M., Gardner, Sharon L., Raetz, Elizabeth A., Shah, Niketa C., Chen, Jing, Krajewski, Jennifer, Hijiya, Nobuko, Satwani, Prakash, Hochberg, Jessica C, Mauguen, Audrey, Curran, Kevin J., Sulis, Maria Luisa

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