ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis von Pepelyayeva, Yuliya, Rastall, David P. W., Aldhamen, Yasser A., O’Connell, Patrick, Raehtz, Sandra, Alyaqoub, Fadel S., Blake, Maja K., Raedy, Ashley M., Angarita, Ariana M., Abbas, Abdulraouf M., Pereira-Hicks, Cristiane N., Roosa, Sarah G., McCabe, Laura, Amalfitano, Andrea

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In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens von Alyaqoub, Fadel S, Aldhamen, Yasser A, Koestler, Benjamin J, Bruger, Eric L, Seregin, Sergey S, Pereira-Hicks, Cristiane, Godbehere, Sarah, Waters, Christopher M, Amalfitano, Andrea

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Modulation by bexarotene of mRNA expression of genes in mouse lung tumors von Alyaqoub, Fadel S., Liu, Yue, Tao, Lianhui, Steele, Vernon E., Lubet, Ronald A., Pereira, Michael A.

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Prevention of mouse lung tumors by targretin von Pereira, Michael A., Kramer, Paula M., Nines, Ronald, Liu, Yue, Alyaqoub, Fadel S., Gunning, William T., Steele, Vernon E., Lubet, Ronald A.

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Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT) von Alyaqoub, Fadel S., Tao, Lianhui, Kramer, Paula M., Steele, Vernon E., Lubet, Ronald A., Gunning, William T., Pereira, Michael A.

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Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT) von Alyaqoub, Fadel S., Tao, Lianhui, Kramer, Paula M., Steele, Vernon E., Lubet, Ronald A., Gunning, William T., Pereira, Michael A.

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Erythroblast transformation-specific transcription factor fusions in prostate cancer von Barbi de Moura, Michelle, Alyaqoub, Fadel S., Basu, Gargi D., Hall, David W., Hoag, Jess R, LoBello, Janine R., Baehner, Frederick L., Thakkar, Snehal Govind, Canfield, Steven

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Prevalence and genomic landscape of BRAF alterations across gastrointestinal cancers von Driscoll, David, Wang, Min, Alyaqoub, Fadel S., Udhane, Sameer S., Szelinger, Szabolcs, Jalkanen, Aimee, Hall, David W., Hoag, Jess R, LoBello, Janine R., Baehner, Frederick L., Thakkar, Snehal Govind, Basu, Gargi D.

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Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT) von Alyaqoub, Fadel S., Tao, Lianhui, Kramer, Paula M., Steele, Vernon E., Lubet, Ronald A., Gunning, William T., Pereira, Michael A.

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Genomic profiling of gastrointestinal cancers by comprehensive tumor-normal sequencing von Alyaqoub, Fadel S., Noel, Pawan, Szelinger, Szabolcs, Natarajan, Thanemozhi G., Dombrowski, Susan M., Ozols, Audrey A., Goodman, Laurie Jane, LoBello, Janine, Royce, Thomas, Basu, Gargi D.

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Comprehensive whole-exome and transcriptome profiling to identify actionable alterations associated with response to PARP inhibitors in breast cancer von Dombrowski, Susan M., Udhane, Sameer S., Basu, Gargi D., Hall, David W., Hoag, Jess W., Alyaqoub, Fadel S., Noel, Pawan, Szelinger, Szabolcs, Wang, Min, Ozols, Audrey A., LoBello, Janine R., Thakkar, Snehal Govind, Baehner, Frederick L., O'Shaughnessy, Joyce

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Apoptotic proteins and cancer: many faces von Alenzi, Faris Q, Salem, Mohamed L, Alyaqoub, Fadel S, Alanazi, Fahad G B, Alanazi, Wafa G, Alanazi, Mona G, Alanazi, Abdulmajeed G, Alanazi, Majed G, Al-Shehri, Hamdan, Abuderman, Abdulwahab A, Tamimi, Waleed

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Comprehensive genomic profiling to identify gene alterations in DNA repair pathway across solid tumors von McDonnell, Kevin, Basu, Gargi D., Hoag, Jess W., Hall, David W., Alyaqoub, Fadel S., Dombrowski, Susan M., Noel, Pawan, Szelinger, Szabolcs, Udhane, Sameer S., Wang, Min, LoBello, Janine R., Thakkar, Snehal Govind, Baehner, Frederick L., Hong, Christine, Park, Wai, Idos, Gregory, Gray, Stacy W., Gruber, Stephen B.

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Abstract 2994: Engineered STING-targeting immunotherapy delays B16 melanoma tumor growth and significantly improves animal survival as compared to an immune-checkpoint inhibitor von Amalfitano, Andrea, Alyaqoub, Fadel S., Aldhamen, Yasser A., Abbas, Abdulraouf, Pereira-Hicks, Cristiane, Godbehere, Sarah, Waters, Christopher M.

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Abstract 1263: Comprehensive genomic profiling to identify biomarkers predictive of response to immunotherapy von Noel, Pawan, Hall, David W., Udhane, Sameer S., Wang, Min, Alyaqoub, Fadel S., Szelinger, Szabolcs, Ozols, Audrey A., LoBello, Janine R., Baehner, Frederick L., Basu, Gargi D.

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Endoplasmic Reticulum Aminopeptidase I-driven Production of IL-18 and IL-1β Protects from Severe Intestinal Inflammation and Mortality during Experimental Colitis von Aldhamen, Yasser Ali, Alyaqoub, Fadel S, Pepelyayeva, Yuliya, Rastall, David P.W., Raedy, Ashley, O’Connell, Patrick, Pereira-Hicks, Cristiane, Godbehere, Sarah, Amalfitano, Andrea

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Abstract A022: Assessment of clonal and subclonal PIK3CA mutations in patients with breast cancer von Udhane, Sameer S, Alyaqoub, Fadel, Noel, Pawan, Kemkes, Ariane, Flannery, Cynthia A, Innis, Paige E, Hall, David W, Thakkar, Snehal G, Basu, Gargi, O'Shaughnessy, Joyce

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Abstract P5-14-12: ESR1-alterations in HR+HER2- breast cancer patients von Basu, Gargi, Udhane, Sameer S., Dombrowski, Susan, Hong, Lenny, Alyaqoub, Fadel, de Moura, Michelle Barbi, Chandrasekaran, Thiruppavai, Dogruluk, Turgut, Driscoll, David, Jalkanen, Aimee, Noel, Pawan, Szelinger, Szabolcs, Wang, Min, Hall, David, Hoag, Jess, Lobello, Janine, Baehner, Frederick, Thakkar, Snehal, O’Shaughnessy, Joyce

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12q14 microdeletion associated with HMGA2 gene disruption and growth restriction von Alyaqoub, Fadel, Pyatt, Robert E., Bailes, Andrea, Brock, Amanda, Deeg, Carol, McKinney, Aimee, Astbury, Caroline, Reshmi, Shalini, Shane, Kate P., Thrush, Devon Lamb, Sommer, Annemarie, Gastier‐Foster, Julie M.

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12q14 microdeletion associated with HMGA2 gene disruption and growth restriction von Alyaqoub, Fadel, Pyatt, Robert E., Bailes, Andrea, Brock, Amanda, Deeg, Carol, McKinney, Aimee, Astbury, Caroline, Reshmi, Shalini, Shane, Kate P., Thrush, Devon Lamb, Sommer, Annemarie, Gastier-Foster, Julie M.

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