Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies von Alvi, Muhammad A, Loughrey, Maurice B, Dunne, Philip, McQuaid, Stephen, Turkington, Richard, Fuchs, Marc-Aurel, McGready, Claire, Bingham, Victoria, Pang, Brendan, Moore, Wendy, Maxwell, Perry, Lawler, Mark, James, Jacqueline A, Murray, Graeme I, Wilson, Richard H, Salto-Tellez, Manuel

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Rare cancers: the greatest inequality in cancer research and oncology treatment von Alvi, Muhammad A, Wilson, Richard H, Salto-Tellez, Manuel

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DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus von ALVI, Muhammad A, XINXUE LIU, FITZGERALD, Rebecca C, O'DONOVAN, Maria, NEWTON, Richard, WERNISCH, Lorenz, SHANNON, Nicholas B, SHARIFF, Kareem, DI PIETRO, Massimiliano, BERGMAN, Jacques J. G. H. M, RAGUNATH, Krish

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Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility von Alvi, Muhammad A, McArt, Darragh G, Kelly, Paul, Fuchs, Marc-Aurel, Alderdice, Matthew, McCabe, Clare M, Bingham, Victoria, McGready, Claire, Tripathi, Shailesh, Emmert-Streib, Frank, Loughrey, Maurice B, McQuaid, Stephen, Maxwell, Perry, Hamilton, Peter W, Turkington, Richard, James, Jacqueline A, Wilson, Richard H, Salto-Tellez, Manuel

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A gene signature associated with PTEN activation defines good prognosis intermediate risk prostate cancer cases von Ong, Chee W, Maxwell, Pamela, Alvi, Muhammad A, McQuaid, Stephen, Waugh, David, Mills, Ian, Salto‐Tellez, Manuel

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Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk von Shrine, Nick, Chen, Jing, Packer, Richard, Hall, Robert J., Guyatt, Anna L., Batini, Chiara, Thompson, Rebecca J., Malik, Vidhi, Moll, Matthew, Tal-Singer, Ruth, Bakke, Per, Fawcett, Katherine A., John, Catherine, Piga, Noemi Nicole, Pozarickij, Alfred, Lin, Kuang, Chen, Zhengming, Li, Liming, Lahousse, Lies, Uitterlinden, Andre G., Oelsner, Elizabeth C., Rich, Stephen S., Kerr, Shona M., Vitart, Veronique, Brown, Michael R., Wielscher, Matthias, Imboden, Medea, Bartz, Traci M., Gharib, Sina A., Flexeder, Claudia, Karrasch, Stefan, Peters, Annette, Hu, Xiaowei, Ortega, Victor E., Meyers, Deborah A., Bleecker, Eugene R., Gupta, Namrata, Smith, Albert Vernon, Luan, Jian’an, Zhao, Jing-Hua, Hansen, Ailin F., Langhammer, Arnulf, Willer, Cristen, Bhatta, Laxmi, Porteous, David, Smith, Blair H., Lee, Jiwon, Daviglus, Martha L., Yu, Bing, Lim, Elise, Xu, Hanfei, O’Connor, George T., Thareja, Gaurav, Suhre, Karsten, Granell, Raquel, Faquih, Tariq O., Hiemstra, Pieter S., Hui, Jennie, James, Alan, Beilby, John, Hysi, Pirro, Koskela, Jukka T., Jin, Jianping, Sikdar, Sinjini, May-Wilson, Sebastian, Kentistou, Katherine A., Free, Robert C., Wang, Xueyang, Gilliland, Frank D., Chen, Zhanghua, Foong, Rachel E., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Cook, James P., Lind, Lars, Lehtimäki, Terho, Pietiläinen, Kirsi H., Pennell, Craig E., Hall, Graham L., Gauderman, W. James, Wilson, James F., Laitinen, Tarja, Salomaa, Veikko, Timpson, Nicholas J., Zeggini, Eleftheria, Dupuis, Josée, Hayward, Caroline, Brumpton, Ben, Weiss, Stefan, Homuth, Georg, Probst-Hensch, Nicole, Jarvelin, Marjo-Riitta, Morrison, Alanna C., Sayers, Ian, Rawlins, Emma L., Strachan, David P., Walters, Robin G., Morris, Andrew P., Tobin, Martin D.

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Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits von Thareja, Gaurav, Al-Sarraj, Yasser, Belkadi, Aziz, Almotawa, Maryam, Suhre, Karsten, Albagha, Omar M. E.

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Su1173 DNA Methylation is a Biomarker for Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus: From Discovery to a Phase 4 Prospective Validation Study von Alvi, Muhammad A, Liu, Xinxue, O'Donovan, Maria, Shannon, Nicholas, Shariff, Kareem M, di Pietro, Massimiliano, Bergman, Jacques J, Ragunath, Krish, Fitzgerald, Rebecca

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Predictors of Outcomes in Patients With Mild Ischemic Stroke Symptoms: MaRISS von Romano, Jose G., Gardener, Hannah, Campo-Bustillo, Iszet, Khan, Yosef, Tai, Sofie, Riley, Nikesha, Smith, Eric E., Sacco, Ralph L., Khatri, Pooja, Alger, Heather M., Mac Grory, Brian, Gulati, Deepak, Sangha, Navdeep S., Craig, Jeffrey M., Olds, Karin E., Benesch, Curtis G., Kelly, Adam G., Brehaut, Scott S., Kansara, Amit C., Schwamm, Lee H.

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Analysis of 14,392 whole genomes reveals 3.5% of Qataris carry medically actionable variants von Elfatih, Amal, Saad, Chadi, Mifsud, Borbala, Mbarek, Hamdi

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Mapping the genetic landscape of treatable inherited metabolic disorders in a large Middle Eastern biobank von Devadoss Gandhi, Geethanjali, Aliyev, Elbay, Syed, Najeeb, Vempalli, Fazulur Rehaman, Saad, Chadi, Mbarek, Hamdi, Al-Saei, Omayma, Al-Maraghi, Aljazi, Abdi, Mona, Krishnamoorthy, Navaneethakrishnan, Badii, Ramin, Ismail, Said I., Al-Muftah, Wadha, Badji, Radja, Mbarek, Hamdi, Darwish, Dima, Fadl, Tasnim, Yasin, Heba, Ennaifar, Maryem, Abdellatif, Rania, Alkuwari, Fatima, Alvi, Muhammad, Al-Sarraj, Yasser, Saad, Chadi, Althani, Asmaa, Fethnou, Eleni, Qafoud, Fatima, Alkhayat, Eiman, Afifi, Nahla, Tomei, Sara, Liu, Wei, Lorenz, Stephan, Syed, Najeeb, Almabrazi, Hakeem, Vempalli, Fazulur Rehaman, Temanni, Ramzi, Saqri, Tariq Abu, Khatib, Mohammedhusen, Hamza, Mehshad, Zaid, Tariq Abu, El Khouly, Ahmed, Pathare, Tushar, Poolat, Shafeeq, Al-Ali, Rashid, Albagha, Omar, Al-Khodor, Souhaila, Alshafai, Mashael, Badii, Ramin, Chouchane, Lotfi, Estivill, Xavier, Fakhro, Khalid A., Mokrab, Younes, Puthen, Jithesh V., Suhre, Karsten, Tatari, Zohreh, Akil, Ammira A., Ben-Omran, Tawfeg, Fakhro, Khalid A.

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Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk von Shrine, Nick, Chen, Jing, Packer, Richard, Hall, Robert J., Guyatt, Anna L., Batini, Chiara, Thompson, Rebecca J., Malik, Vidhi, Moll, Matthew, Tal-Singer, Ruth, Bakke, Per, Fawcett, Katherine A., John, Catherine, Piga, Noemi Nicole, Pozarickij, Alfred, Lin, Kuang, Chen, Zhengming, Li, Liming, Lahousse, Lies, Uitterlinden, Andre G., Oelsner, Elizabeth C., Rich, Stephen S., Kerr, Shona M., Vitart, Veronique, Brown, Michael R., Wielscher, Matthias, Imboden, Medea, Bartz, Traci M., Gharib, Sina A., Flexeder, Claudia, Karrasch, Stefan, Peters, Annette, Hu, Xiaowei, Ortega, Victor E., Meyers, Deborah A., Bleecker, Eugene R., Gupta, Namrata, Smith, Albert Vernon, Luan, Jian’an, Zhao, Jing-Hua, Hansen, Ailin F., Langhammer, Arnulf, Willer, Cristen, Bhatta, Laxmi, Porteous, David, Smith, Blair H., Lee, Jiwon, Daviglus, Martha L., Yu, Bing, Lim, Elise, Xu, Hanfei, O’Connor, George T., Thareja, Gaurav, Suhre, Karsten, Granell, Raquel, Faquih, Tariq O., Hiemstra, Pieter S., Hui, Jennie, James, Alan, Beilby, John, Hysi, Pirro, Koskela, Jukka T., Jin, Jianping, Sikdar, Sinjini, May-Wilson, Sebastian, Kentistou, Katherine A., Free, Robert C., Wang, Xueyang, Gilliland, Frank D., Chen, Zhanghua, Foong, Rachel E., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Cook, James P., Lind, Lars, Lehtimäki, Terho, Pietiläinen, Kirsi H., Pennell, Craig E., Hall, Graham L., Gauderman, W. James, Wilson, James F., Laitinen, Tarja, Salomaa, Veikko, Timpson, Nicholas J., Zeggini, Eleftheria, Dupuis, Josée, Hayward, Caroline, Brumpton, Ben, Weiss, Stefan, Homuth, Georg, Probst-Hensch, Nicole, Jarvelin, Marjo-Riitta, Morrison, Alanna C., Sayers, Ian, Rawlins, Emma L., Strachan, David P., Walters, Robin G., Morris, Andrew P., Tobin, Martin D.

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Frequency and Prognostic Significance of Clinical Fluctuations Before Hospital Arrival in Stroke von Romano, Jose G., Gardener, Hannah, Smith, Eric E., Campo-Bustillo, Iszet, Khan, Yosef, Tai, Sofie, Riley, Nikesha, Sacco, Ralph L., Khatri, Pooja, Alger, Heather M., Mac Grory, Brian, Gulati, Deepak, Sangha, Navdeep S., Olds, Karin E., Benesch, Curtis G., Kelly, Adam G., Brehaut, Scott S., Kansara, Amit C., Schwamm, Lee H.

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Burden of Mendelian disorders in a large Middle Eastern biobank von Aamer, Waleed, Al-Maraghi, Aljazi, Syed, Najeeb, Gandhi, Geethanjali Devadoss, Aliyev, Elbay, Al-Kurbi, Alya A, Al-Saei, Omayma, Kohailan, Muhammad, Krishnamoorthy, Navaneethakrishnan, Palaniswamy, Sasirekha, Al-Malki, Khulod, Abbasi, Saleha, Agrebi, Nourhen, Abbaszadeh, Fatemeh, Akil, Ammira S Al-Shabeeb, Badii, Ramin, Ben-Omran, Tawfeg, Lo, Bernice, Mokrab, Younes, Fakhro, Khalid A

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A population study of clinically actionable genetic variation affecting drug response from the Middle East von Jithesh, Puthen Veettil, Abuhaliqa, Mohammed, Syed, Najeeb, Ahmed, Ikhlak, El Anbari, Mohammed, Bastaki, Kholoud, Sherif, Shimaa, Umlai, Umm-Kulthum, Jan, Zainab, Gandhi, Geethanjali, Manickam, Chidambaram, Selvaraj, Senthil, George, Chinnu, Bangarusamy, Dhinoth, Abdel-latif, Rania, Al-Shafai, Mashael, Tatari-Calderone, Zohreh, Estivill, Xavier, Pirmohamed, Munir

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Abstract 1555: A gene signature associated with PTEN activation defines good outcomes in intermediate-risk prostate cancer cases von Ong, Chee Wee, Maxwell, Pamela, Alvi, Muhammad A., McQuaid, Stephen, Mills, Ian G., Salto-Tellez, Manuel, Waugh, David J.

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Abstract 4792: Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with clinical utility von Alvi, Muhammad A., McArt, Darragh G., Kelly, Paul, Fuchs, Marc-Aurel, Alderdice, Matthew, McCabe, Clare M., Bingham, Victoria, McGready, Claire, McQuaid, Stephen, Maxwell, Perry, Hamilton, Peter, James, Jacqueline A., Wilson, Richard, Salto-Tellez, Manuel

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Abstract 2256: Novel prognostic targets identified using integrated analysis of copy number and expression data in esophageal adenocarcinoma von Goh, Xin Yi, Alvi, Muhammad A., Rees, Jonathan RE, Chin, Suet-Feung, Weaver, Jamie MJ, Caldas, Carlos, Fitzgerald, Rebecca C.

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Antibiotic resistance: a rundown of a global crisis von Aslam, Bilal, Wang, Wei, Arshad, Muhammad Imran, Khurshid, Mohsin, Muzammil, Saima, Rasool, Muhammad Hidayat, Nisar, Muhammad Atif, Alvi, Ruman Farooq, Aslam, Muhammad Aamir, Qamar, Muhammad Usman, Salamat, Muhammad Khalid Farooq, Baloch, Zulqarnain

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Molecular surveillance based on anaplasmosis in domestic small ruminants: First report on zoonotic Anaplasma capra and phylogenetic insights from Faisalabad, Pakistan von Razzaq, Muhammad A, Imran, Muhammad, Atif, Farhan Ahmad, Abbas, Rao Z, Alvi, Mughees A, Swelum, Ayman A, Sindhu, Zia-Ud-Din, Khan, Muhammad K, Sabir Mughal, Muhammad A, Khan, Adil, Wu, Wen-Feng

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