PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer von Raina, Kanak, Lu, Jing, Qian, Yimin, Altieri, Martha, Gordon, Deborah, Rossi, Ann Marie K., Wang, Jing, Chen, Xin, Dong, Hanqing, Siu, Kam, Winkler, James D., Crew, Andrew P., Crews, Craig M., Coleman, Kevin G.

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Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 von Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Hines, John, Winkler, James D., Crew, Andrew P., Coleman, Kevin, Crews, Craig M.

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In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes von Wen, L, Wong, F S, Tang, J, Chen, N Y, Altieri, M, David, C, Flavell, R, Sherwin, R

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Potent and Orally Bioavailable BCL6 PROTAC TM Degraders Demonstrate Efficacy in Pre-Clinical Models of Diffuse Large B-Cell Lymphoma (DLBCL) von Gough, Sheryl M, Sherman, Dan, DeCarr, Lynn, Eaton, Sarah, Milanovic, Maja, Bookbinder, Mark, Pizzano, Jennifer, Altieri, Martha, Corradi, John, Xiao, Hong, Gallego, Felipe, Soto, Leofal, Lingamaneni, Ram, Chen, Xin, Zhang, Wei, Wang, Gan, Dong, Hanqing, Chirnomas, Deborah, Berlin, Michael, Hornberger, Keith, Snyder, Lawrence, Taylor, Ian

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Abstract 5076: IHC and flow cytometry quantifies BRD4 levels in surrogate tissues after ex-vivo and in-vivo dosing with a BRD4 degrading PROTAC von Gough, Sheryl M., Raina, Kanak, Gordon, Debbie, Willard, Ryan, Altieri, Martha, Shen, Angela, Qian, Yimin, Neklesa, Taavi, Coleman, Kevin, Taylor, Ian

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Abstract 4710: BRD4 degradation by PROTACs represents a more effective therapeutic strategy than BRD4 inhibitors in ovarian cancer von Raina, Kanak, Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Chen, Xin, Crew, Andrew, Coleman, Kevin, Crews, Craig, Winkler, James

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BRD4 Degradation By Protacs Represents a More Effective Therapeutic Strategy Than BRD4 Inhibitors in DLBCL von Lu, Jing, Qian, Yimin, Raina, Kanak, Altieri, Martha, Dong, Hanqing, Wang, Jing, Chen, Xin, Crew, Andrew, Coleman, Kevin, Crews, Craig, Winkler, James

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Abstract LB-010: Hijacking the E3 ubiquitin ligase cereblon to create efficient BRD4 degraders von Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Winkler, Jim, Crew, Andy, Coleman, Kevin, Hines, John, Crews, Craig

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BRD4 degraders produce long-lasting loss of BRD4 Ppotein and robust efficacy in Burkitt’s lymphoma cells von Coleman, Kevin, Lu, Jing, Qian, Yimin, Altieri, Martha, Raina, Kanak, Dong, Hanqing, Wang, Jing, Hines, John, Crew, Andrew P, Crews, Craig M

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GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice von Zekzer, D, Wong, F S, Ayalon, O, Millet, I, Altieri, M, Shintani, S, Solimena, M, Sherwin, R S

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Substituted aminobenzimidazole pyrimidines as cyclin-dependent kinase inhibitors von Verma, Sharad, Nagarathnam, Dhanapalan, Shao, Jianxing, Zhang, Lei, Zhao, Jin, Wang, Yamin, Li, Tindy, Mull, Eric, Enyedy, Istvan, Wang, Chunguang, Zhu, Qingming, Altieri, Martha, Jordan, Jerold, Dang, Thu-Thi-Anh, Reddy, Sanjeeva

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Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice von Wen, L, Wong, F S, Burkly, L, Altieri, M, Mamalaki, C, Kioussis, D, Flavell, R A, Sherwin, R S

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The Spectrum of Comet Hale-Bopp (C/1995 01) Observed with the Infrared Space Observatory at 2.9 Astronomical Units from the Sun von Crovisier, Jacques, Leech, Kieron, Bockelée-Morvan, Dominique, Brooke, Timothy Y., Hanner, Martha S., Altieri, Bruno, Keller, H. Uwe, Lellouch, Emmanuel

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Shorter Reviews von Sirridge, Mary, Nussbaum, Martha, Murray, Michael, McGraw, Betty R, Atkins, G Douglas, Altieri, Charles, Murchland, Bernard, Palmer, Richard E, Thornton, R K R

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Book reviews von Alexander, David, Brenner, Fred J., Gittleman, John L., Salk, Martha S., Foster, Harold F., Suter, Glenn W., Moore, James W., Budd, William W., Altieri, Miguel A.

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