Arid1a restrains Kras-dependent changes in acinar cell identity von Livshits, Geulah, Alonso-Curbelo, Direna, Morris, 4th, John P, Koche, Richard, Saborowski, Michael, Wilkinson, John Erby, Lowe, Scott W

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Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimics von Olmeda, David, Cerezo‐Wallis, Daniela, Mucientes, Cynthia, Calvo, Tonantzin G, Cañón, Estela, Alonso‐Curbelo, Direna, Ibarz, Nuria, Muñoz, Javier, Rodriguez‐Peralto, José L, Ortiz‐Romero, Pablo, Ortega, Sagrario, Soengas, María S

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BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance von Tasdemir, Nilgun, Banito, Ana, Roe, Jae-Seok, Alonso-Curbelo, Direna, Camiolo, Matthew, Tschaharganeh, Darjus F, Huang, Chun-Hao, Aksoy, Ozlem, Bolden, Jessica E, Chen, Chi-Chao, Fennell, Myles, Thapar, Vishal, Chicas, Agustin, Vakoc, Christopher R, Lowe, Scott W

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An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants von Zafra, Maria Paz, Parsons, Marie J, Kim, Jangkyung, Alonso-Curbelo, Direna, Goswami, Sukanya, Schatoff, Emma M, Han, Teng, Katti, Alyna, Fernandez, Maria Teresa Calvo, Wilkinson, John E, Piskounova, Elena, Dow, Lukas E

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Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer von Escobar-Hoyos, Luisa F., Penson, Alex, Kannan, Ram, Cho, Hana, Pan, Chun-Hao, Singh, Rohit K., Apken, Lisa H., Hobbs, G. Aaron, Luo, Renhe, Lecomte, Nicolas, Babu, Sruthi, Pan, Fong Cheng, Alonso-Curbelo, Direna, Morris, John P., Askan, Gokce, Grbovic-Huezo, Olivera, Ogrodowski, Paul, Bermeo, Jonathan, Saglimbeni, Joseph, Cruz, Cristian D., Ho, Yu-Jui, Lawrence, Sharon A., Melchor, Jerry P., Goda, Grant A., Bai, Karen, Pastore, Alessandro, Hogg, Simon J., Raghavan, Srivatsan, Bailey, Peter, Chang, David K., Biankin, Andrew, Shroyer, Kenneth R., Wolpin, Brian M., Aguirre, Andrew J., Ventura, Andrea, Taylor, Barry, Der, Channing J., Dominguez, Daniel, Kümmel, Daniel, Oeckinghaus, Andrea, Lowe, Scott W., Bradley, Robert K., Abdel-Wahab, Omar, Leach, Steven D.

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p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors von Karras, Panagiotis, Riveiro-Falkenbach, Erica, Cañón, Estela, Tejedo, Cristina, Calvo, Tonantzin G., Martínez-Herranz, Raúl, Alonso-Curbelo, Direna, Cifdaloz, Metehan, Perez-Guijarro, Eva, Gómez-López, Gonzalo, Ximenez-Embun, Pilar, Muñoz, Javier, Megias, Diego, Olmeda, David, Moscat, Jorge, Ortiz-Romero, Pablo L., Rodríguez-Peralto, Jose L., Soengas, María S.

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Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity von Finley, Lydia W. S., Vardhana, Santosha A., Carey, Bryce W., Alonso-Curbelo, Direna, Koche, Richard, Chen, Yanyang, Wen, Duancheng, King, Bryan, Radler, Megan R., Rafii, Shahin, Lowe, Scott W., Allis, C. David, Thompson, Craig B.

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Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control von Kozuka, Chisayo, Efthymiou, Vissarion, Sales, Vicencia M, Zhou, Liyuan, Osataphan, Soravis, Yuchi, Yixing, Chimene-Weiss, Jeremy, Mulla, Christopher, Isganaitis, Elvira, Desmond, Jessica, Sanechika, Suzuka, Kusuyama, Joji, Goodyear, Laurie, Shi, Xu, Gerszten, Robert E, Aguayo-Mazzucato, Cristina, Carapeto, Priscila, Teixeira, Silvania DaSilva, Sandoval, Darleen, Alonso-Curbelo, Direna, Wu, Lei, Qi, Jun, Patti, Mary-Elizabeth

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Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers von Osmanbeyoglu, Hatice U., Shimizu, Fumiko, Rynne-Vidal, Angela, Alonso-Curbelo, Direna, Chen, Hsuan-An, Wen, Hannah Y., Yeung, Tsz-Lun, Jelinic, Petar, Razavi, Pedram, Lowe, Scott W., Mok, Samuel C., Chiosis, Gabriela, Levine, Douglas A., Leslie, Christina S.

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Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers von Pérez-Guijarro, Eva, Karras, Panagiotis, Cifdaloz, Metehan, Martínez-Herranz, Raúl, Cañón, Estela, Graña, Osvaldo, Horcajada-Reales, Celia, Alonso-Curbelo, Direna, Calvo, Tonantzin G., Gómez-López, Gonzalo, Bellora, Nicolas, Riveiro-Falkenbach, Erica, Ortiz-Romero, Pablo L., Rodríguez-Peralto, José L., Maestre, Lorena, Roncador, Giovanna, de Agustín Asensio, Juan C., Goding, Colin R., Eyras, Eduardo, Megías, Diego, Méndez, Raúl, Soengas, María S.

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Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells von Tormo, Damià, Chęcińska, Agnieszka, Alonso-Curbelo, Direna, Pérez-Guijarro, Eva, Cañón, Estela, Riveiro-Falkenbach, Erica, Calvo, Tonantzin G., Larribere, Lionel, Megías, Diego, Mulero, Francisca, Piris, Miguel A., Dash, Rupesh, Barral, Paola M., Rodríguez-Peralto, José L., Ortiz-Romero, Pablo, Tüting, Thomas, Fisher, Paul B., Soengas, María S.

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Cancer spread in the liver is unlocked from within von Woess, Katharina, Alonso-Curbelo, Direna

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Normal liver cells unlock cancer spread von Woess, Katharina, Alonso-Curbelo, Direna

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Self-killing of melanoma cells by cytosolic delivery of dsRNA: Wiring innate immunity for a coordinated mobilization of endosomes, autophagosomes and the apoptotic machinery in tum... von Alonso-Curbelo, Direna, Soengas, María S.

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Abstract A019: Neoplastic co-option of epithelial-immune interactions in pancreatic cancer von Alonso-Curbelo, Direna

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Senolytic CAR T cells reverse senescence-associated pathologies von Amor, Corina, Feucht, Judith, Leibold, Josef, Ho, Yu-Jui, Zhu, Changyu, Alonso-Curbelo, Direna, Mansilla-Soto, Jorge, Boyer, Jacob A., Li, Xiang, Giavridis, Theodoros, Kulick, Amanda, Houlihan, Shauna, Peerschke, Ellinor, Friedman, Scott L., Ponomarev, Vladimir, Piersigilli, Alessandra, Sadelain, Michel, Lowe, Scott W.

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A temporal perspective for tumor-associated macrophage identities and functions von Blériot, Camille, Dunsmore, Garett, Alonso-Curbelo, Direna, Ginhoux, Florent

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Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer von Ruscetti, Marcus, Morris, John P., Mezzadra, Riccardo, Russell, James, Leibold, Josef, Romesser, Paul B., Simon, Janelle, Kulick, Amanda, Ho, Yu-jui, Fennell, Myles, Li, Jinyang, Norgard, Robert J., Wilkinson, John E., Alonso-Curbelo, Direna, Sridharan, Ramya, Heller, Daniel A., de Stanchina, Elisa, Stanger, Ben Z., Sherr, Charles J., Lowe, Scott W.

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Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity von Chen, Hsuan-An, Ho, Yu-Jui, Mezzadra, Riccardo, Adrover, Jose M, Smolkin, Ryan, Zhu, Changyu, Woess, Katharina, Bernstein, Nicholas, Schmitt, Georgia, Fong, Linda, Luan, Wei, Wuest, Alexandra, Tian, Sha, Li, Xiang, Broderick, Caroline, Hendrickson, Ronald C, Egeblad, Mikala, Chen, Zhenghao, Alonso-Curbelo, Direna, Lowe, Scott W

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A gene–environment-induced epigenetic program initiates tumorigenesis von Alonso-Curbelo, Direna, Ho, Yu-Jui, Burdziak, Cassandra, Maag, Jesper L. V., Morris, John P., Chandwani, Rohit, Chen, Hsuan-An, Tsanov, Kaloyan M., Barriga, Francisco M., Luan, Wei, Tasdemir, Nilgun, Livshits, Geulah, Azizi, Elham, Chun, Jaeyoung, Wilkinson, John E., Mazutis, Linas, Leach, Steven D., Koche, Richard, Pe’er, Dana, Lowe, Scott W.

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