A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay von Alexander-Howden, Beatrice, Zhang, Li, van der Sloot, Almer M., Tollis, Sylvain, St-Cyr, Daniel J., Sicheri, Frank, Bird, Adrian P., Tyers, Mike, Lyst, Matthew J.

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Evaluating CHARGE syndrome in congenital hypogonadotropic hypogonadism patients harboring CHD7 variants von Xu, Cheng, Cassatella, Daniele, van der Sloot, Almer M, Quinton, Richard, Hauschild, Michael, De Geyter, Christian, Flück, Christa, Feller, Katrin, Bartholdi, Deborah, Nemeth, Attila, Halperin, Irene, Pekic Djurdjevic, Sandra, Maeder, Philippe, Papadakis, Georgios, Dwyer, Andrew A, Marino, Laura, Favre, Lucie, Pignatelli, Duarte, Niederländer, Nicolas J, Acierno, James, Pitteloud, Nelly

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Targeting AML through DR4 with a novel variant of rhTRAIL von Szegezdi, Eva, Reis, Carlos R., Sloot, Almer M. van der, Natoni, Alessandro, O’Reilly, Aoife, Reeve, Janice, Cool, Robbert H., O’Dwyer, Michael, Knapper, Steven, Serrano, Luis, Quax, Wim J., Samali, Afshin

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Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity von Carleton, Laura A., Chakravarthy, Reka, van der Sloot, Almer M., Mnich, Katarzyna, Serrano, Luis, Samali, Afshin, Gorman, Adrienne M.

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DR4-selective Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Variants Obtained by Structure-based Design von Tur, Vicente, van der Sloot, Almer M., Reis, Carlos R., Szegezdi, Eva, Cool, Robbert H., Samali, Afshin, Serrano, Luis, Quax, Wim J.

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Building blocks for protein interaction devices von Grünberg, Raik, Ferrar, Tony S, van der Sloot, Almer M, Constante, Marco, Serrano, Luis

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Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development von Jacques, Samuel, van der Sloot, Almer M, C. Huard, Caroline, Coulombe-Huntington, Jasmin, Tsao, Sarah, Tollis, Sylvain, Bertomeu, Thierry, Culp, Elizabeth J, Pallant, Daniel, Cook, Michael A, Bonneil, Eric, Thibault, Pierre, Wright, Gerard D, Tyers, Mike

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RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor von MENACHO, Ivan Plaza, KOSTER, Roelof, EGGEN, Bart J. L, HOFSTRA, Robert M. W, VAN DER SLOOT, Almer M, QUAX, Wim J, OSINGA, Jan, VAN DER SLUIS, Tineke, HOLLEMA, Harry, BURZYNSKI, Grzegorz M, GIMM, Oliver, BUYS, Charles H. C. M

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Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality von Mast, Fred D., Navare, Arti T., van der Sloot, Almer M., Coulombe-Huntington, Jasmin, Rout, Michael P., Baliga, Nitin S., Kaushansky, Alexis, Chait, Brian T., Aderem, Alan, Rice, Charles M., Sali, Andrej, Tyers, Mike, Aitchison, John D.

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Protein design in biological networks: from manipulating the input to modifying the output von Van der Sloot, Almer M., Kiel, Christina, Serrano, Luis, Stricher, Francois

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Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex von St-Cyr, Daniel, Ceccarelli, Derek F., Orlicky, Stephen, van der Sloot, Almer M., Tang, Xiaojing, Kelso, Susan, Moore, Susan, James, Clint, Posternak, Ganna, Coulombe-Huntington, Jasmin, Bertomeu, Thierry, Marinier, Anne, Sicheri, Frank, Tyers, Mike

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Protein design with fragment databases von Verschueren, Erik, Vanhee, Peter, van der Sloot, Almer M, Serrano, Luis, Rousseau, Frederic, Schymkowitz, Joost

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A novel classification system to predict the pathogenic effects of CHD7 missense variants in CHARGE syndrome von Bergman, Jorieke E.H., Janssen, Nicole, van der Sloot, Almer M., de Walle, Hermien E.K., Schoots, Jeroen, Rendtorff, Nanna D., Tranebjærg, Lisbeth, Hoefsloot, Lies H., van Ravenswaaij-Arts, Conny M.A., Hofstra, Robert M.W.

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Engineering of weak helper interactions for high-efficiency FRET probes von Grünberg, Raik, Burnier, Julia V, Ferrar, Tony, Beltran-Sastre, Violeta, Stricher, François, van der Sloot, Almer M, Garcia-Olivas, Raquel, Mallabiabarrena, Arrate, Sanjuan, Xavier, Zimmermann, Timo, Serrano, Luis

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Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Death Receptors von Reis, Carlos R, van der Sloot, Almer M, Szegezdi, Eva, Natoni, Alessandro, Tur, Vicente, Cool, Robbert H, Samali, Afshin, Serrano, Luis, Quax, Wim J

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T-RMSD: A Fine-grained, Structure-based Classification Method and its Application to the Functional Characterization of TNF Receptors von Magis, Cedrik, Stricher, François, van der Sloot, Almer M., Serrano, Luis, Notredame, Cedric

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RGD-avidin-biotin pretargeting to αvβ₃ integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand (TRAIL) von Tarrus, Marc, van der Sloot, Almer M, Temming, Kai, Lacombe, Marie, Opdam, Frank, Quax, Wim J, Molema, Grietje, Poelstra, Klaas, Kok, Robbert J

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Mutational Analysis of a Key Residue in the Substrate Specificity of a Cephalosporin Acylase von Otten, Linda G, Sio, Charles F, van der Sloot, Almer M, Cool, Robbert H, Quax, Wim J

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Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity von Carleton, Laura A, Chakravarthy, Reka, van der Sloot, Almer M, Mnich, Katarzyna, Serrano, Luis, Samali, Afshin, Gorman, Adrienne M

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Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme – ubiquitin complex von St-Cyr, Daniel, Ceccarelli, Derek F., Orlicky, Stephen, van der Sloot, Almer M., Tang, Xiaojing, Kelso, Susan, Moore, Susan, James, Clint, Posternak, Ganna, Coulombe-Huntington, Jasmin, Bertomeu, Thierry, Marinier, Anne, Sicheri, Frank, Tyers, Mike

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