Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA von Patel, Siddharth, Ashwanikumar, N, Robinson, Emily, DuRoss, Allison, Sun, Conroy, Murphy-Benenato, Kerry E, Mihai, Cosmin, Almarsson, Örn, Sahay, Gaurav

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Impact of lipid nanoparticle size on mRNA vaccine immunogenicity von Hassett, Kimberly J., Higgins, Jaclyn, Woods, Angela, Levy, Becca, Xia, Yan, Hsiao, Chiaowen Joyce, Acosta, Edward, Almarsson, Örn, Moore, Melissa J., Brito, Luis A.

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Systemic Exposure, Metabolism, and Elimination of [ 14 C]-Labeled Amino Lipid, Lipid 5, after a Single Administration of mRNA Encapsulating Lipid Nanoparticles to Sprague-Dawley Ra... von Burdette, Douglas, Ci, Lei, Shilliday, Barclay, Slauter, Richard, Auerbach, Andrew, Kenney, Matthew, Almarsson, Örn, Cheung, Eugene, Hendrick, Tracy

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The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case von Oude Blenke, Erik, Örnskov, Eivor, Schöneich, Christian, Nilsson, Gunilla A., Volkin, David B., Mastrobattista, Enrico, Almarsson, Örn, Crommelin, Daan J.A.

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Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines? von Almarsson, Orn, Zaworotko, Michael J

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A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates von Sabnis, Staci, Kumarasinghe, E. Sathyajith, Salerno, Timothy, Mihai, Cosmin, Ketova, Tatiana, Senn, Joseph J., Lynn, Andy, Bulychev, Alex, McFadyen, Iain, Chan, Joyce, Almarsson, Örn, Stanton, Matthew G., Benenato, Kerry E.

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Biodistribution of Lipid 5, mRNA, and Its Translated Protein Following Intravenous Administration of mRNA-Encapsulated Lipid Nanoparticles in Rats von Ci, Lei, Hard, Marjie, Zhang, Hannah, Gandham, Srujan, Hua, Serenus, Wickwire, John, Wehrman, Tod, Slauter, Richard, Auerbach, Andrew, Kenney, Matthew, Mercer, Greg, Hendrick, Tracy, Almarsson, Örn, Cheung, Eugene, Burdette, Douglas

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Drugs as materials: valuing physical form in drug discovery von Gardner, Colin R, Walsh, Christopher T, Almarsson, Örn

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Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA von Patel, Siddharth, Ashwanikumar, N., Robinson, Ema, Xia, Yan, Mihai, Cosmin, Griffith, Joseph P., Hou, Shangguo, Esposito, Adam A., Ketova, Tatiana, Welsher, Kevin, Joyal, John L., Almarsson, Örn, Sahay, Gaurav

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Aripiprazole and Dehydro-Aripiprazole Solid Solutions: Crystalline Combinations of Drug and Active Metabolite in Tailored Compositions von Trotta, Jacob T., Zeidan, Tarek A., Tilak, Pranoti A., Foxman, Bruce M., Almarsson, Orn, Oliveira, Mark A., Chiarella, Renato A., Hickey, Magali B., Remenar, Julius F.

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Long-Acting Atypical Antipsychotics: Characterization of the Local Tissue Response von Paquette, Sara Montminy, Dawit, Had, Hickey, Magali B., Merisko-Liversidge, Elaine, Almarsson, Örn, Deaver, Daniel R.

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Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses von Bahl, Kapil, Senn, Joe J., Yuzhakov, Olga, Bulychev, Alex, Brito, Luis A., Hassett, Kimberly J., Laska, Michael E., Smith, Mike, Almarsson, Örn, Thompson, James, Ribeiro, Amilcar (Mick), Watson, Mike, Zaks, Tal, Ciaramella, Giuseppe

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Performance comparison of a co-crystal of carbamazepine with marketed product von Hickey, Magali B., Peterson, Matthew L., Scoppettuolo, Lisa A., Morrisette, Sherry L., Vetter, Anna, Guzmán, Hector, Remenar, Julius F., Zhang, Zhong, Tawa, Mark D., Haley, Sean, Zaworotko, Michael J., Almarsson, Örn

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Structural Diversity of Brexpiprazole and Related Analogues: Impact on Solubility and Drug Delivery von Zeidan, Tarek A, Tilak, Pranoti A, Trotta, Jacob T, Curran, Erin, Oliveira, Mark A, Chiarella, Renato A, Almarsson, Örn, Hickey, Magali B

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Crystal Engineering of Novel Cocrystals of a Triazole Drug with 1,4-Dicarboxylic Acids von Remenar, Julius F, Morissette, Sherry L, Peterson, Matthew L, Moulton, Brian, MacPhee, J. Michael, Guzmán, Héctor R, Almarsson, Örn

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Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses von Bahl, Kapil, Senn, Joe J., Yuzhakov, Olga, Bulychev, Alex, Brito, Luis A., Hassett, Kimberly J., Laska, Michael E., Smith, Mike, Almarsson, Örn, Thompson, James, Ribeiro, Amilcar (Mick), Watson, Mike, Zaks, Tal, Ciaramella, Giuseppe

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High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids von Morissette, Sherry L., Almarsson, Örn, Peterson, Matthew L., Remenar, Julius F., Read, Michael J., Lemmo, Anthony V., Ellis, Steve, Cima, Michael J., Gardner, Colin R.

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Elucidation of Crystal Form Diversity of the HIV Protease Inhibitor Ritonavir by High-Throughput Crystallization von Morissette, Sherry L., Soukasene, Stephen, Levinson, Douglas, Cima, Michael J., Almarsson, Örn

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Prodrugs of Pioglitazone for Extended-Release (XR) Injectable Formulations von Sanrame, Carlos N, Remenar, Julius F, Blumberg, Laura C, Waters, Julie, Dean, Reginald L, Dong, Nan, Kriksciukaite, Kristi, Cao, Peixin, Almarsson, Örn

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Pharmaceutical cocrystals: along the path to improved medicines von Duggirala, Naga K, Perry, Miranda L, Almarsson, Örn, Zaworotko, Michael J

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